Patents Assigned to Medicure Inc.
  • Pyridoxal analogues and methods of treatment
    Patent number: 6890943
    Abstract: Pyridoxal analogues can be useful for treating B6 deficiency and related diseases; cardiovascular and related diseases; melanoma and related diseases; and symptoms thereof. One such analogue is a compound of the formula: or a pharmaceutically acceptable acid addition salt thereof, in which R1 is alkyl, alkenyl, in which alkyl or alkenyl can be interrupted by nitrogen, oxygen, or sulfur, and can be substituted at the terminal carbon by hydroxy, alkoxy, alkanoyloxy, alkanoyloxyaryl, alkoxyalkanoyl, alkoxycarbonyl, or dialkylcarbamoyloxy; alkoxy; dialkylamino; alkanoyloxy; alkanoyloxyaryl; alkoxyalkanoyl; alkoxycarbonyl; dialkylcarbamoyloxy; or aryl, aryloxy, arylthio, or aralkyl, in which aryl can be substituted by alkyl, alkoxy, amino, hydroxy, halo, nitro, or alkanoyloxy. These analogues can be administered, either alone or concurrently with known medications, to treat the above-described diseases.
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: May 10, 2005
    Assignees: Medicure Inc., The University of Manitoba
    Inventor: Wasimul Haque
  • Pyridoxal analogues and methods of treatment
    Publication number: 20030195236
    Abstract: Pyridoxal analogues can be useful for treating B6 deficiency and related diseases; cardiovascular and related diseases; melanoma and related diseases; and symptoms thereof.
    Type: Application
    Filed: June 3, 2003
    Publication date: October 16, 2003
    Applicants: Medicure Inc., The University of Manitoba
    Inventor: Wasimul Haque
  • Pyridoxal analogues and methods of treatment
    Publication number: 20010031770
    Abstract: Pyridoxal analogues can be useful for treating B6 deficiency and related diseases; cardiovascular and related diseases; melanoma and related diseases; and symptoms thereof.
    Type: Application
    Filed: May 22, 2001
    Publication date: October 18, 2001
    Applicant: Medicure Inc.
    Inventor: Wasimul Haque
  • Treatment of cardiovascular and related pathologies
    Patent number: 6043259
    Abstract: Compositions and methods for treatment and prevention of hypertrophy, hypertension, congestive heart failure, ischemic heart disease, ischemia-related conditions, such as ischemia reperfusion injury and cellular dysfunction, are described. The methods are directed to administering pharmaceutical compositions containing at least one compound selected from pyridoxal-5'-phosphate, pyridoxine, pyridoxal, and pyridoxamine.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: March 28, 2000
    Assignees: Medicure Inc., University of Manitoba
    Inventors: Naranjan S. Dhalla, Rajat Sethi, Krishnamurti Dakshinamurti