Patents Assigned to Medicyte GmbH
  • HEPATOCYTES FOR IN VITRO GENOTOXICITY TESTS
    Publication number: 20130323721
    Abstract: The invention relates to a method for carrying out genotoxicity tests of chemical, biological and physical active substances or agents with the aid of cell culture systems of proliferating physiologically active liver cells.
    Type: Application
    Filed: October 4, 2011
    Publication date: December 5, 2013
    Applicant: MEDICYTE GMBH
    Inventors: Adrianus J.C.M. Braspenning, Stefan Heinz, Astrid Nörenberg, Nicola Hewitt, Jan-Heiner Küpper
  • Substances causing differentiation
    Patent number: 8568972
    Abstract: A DNA construct is described which contains a fusion gene under the control of a promoter. The fusion gene comprises at least one resistance gene and at least one reporter gene and is slightly toxic to a host cell transfected with that DNA construct. That DNA construct can be encoded on a plasmid or a virus. Further, a method is described for using the DNA construct to identify substances that may cause a differentiation in eukaryotic cells.
    Type: Grant
    Filed: July 6, 2009
    Date of Patent: October 29, 2013
    Assignee: Medicyte GmbH
    Inventors: Jan-Heiner Kuepper, Reinhard Kandolf, Ralph Meyer