Patents Assigned to Medifron DBT Co., Ltd.
  • Patent number: 8580848
    Abstract: The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: November 12, 2013
    Assignees: Daewoong Pharmaceutical Co., Ltd., Medifron DBT Co., Ltd.
    Inventors: Dong Wook Kang, Jee Woo Lee, Young Ho Kim, Hee Kim, Hee Jin Ha, Eun Joo Nam, Chan Mi Joung
  • Patent number: 8507553
    Abstract: The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: August 13, 2013
    Assignees: Daewoong Pharmaceutical Co., Ltd., Medifron DBT Co., Ltd.
    Inventors: Dong Wook Kang, Jee Woo Lee, Young Ho Kim, Hee Kim, Hee Jin Ha, Eun Joo Nam, Chan Mi Joung
  • Patent number: 8455542
    Abstract: The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
    Type: Grant
    Filed: June 5, 2012
    Date of Patent: June 4, 2013
    Assignees: Daewoong Pharmaceutical Co., Ltd., Medifron DBT Co., Ltd.
    Inventors: Dong Wook Kang, Jee Woo Lee, Young Ho Kim, Hee Kim, Hee Jin Ha, Eun Joo Nam, Chan Mi Joung
  • Publication number: 20120259006
    Abstract: The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
    Type: Application
    Filed: June 5, 2012
    Publication date: October 11, 2012
    Applicants: DAEWOONG PHARMACEUTICAL CO., LTD, MEDIFRON DBT CO., LTD.
    Inventors: Dong Wook KANG, Jee Woo LEE, Young Ho KIM, Hee KIM, Hee Jin HA, Eun Joo NAM, Chan Mi JOUNG
  • Publication number: 20120245165
    Abstract: The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
    Type: Application
    Filed: June 5, 2012
    Publication date: September 27, 2012
    Applicants: DAEWOONG PHARMACEUTICAL CO., LTD, MEDIFRON DBT CO., LTD.
    Inventors: Dong Wook KANG, Jee Woo LEE, Young Ho KIM, Hee KIM, Hee Jin HA, Eun Joo NAM, Chan Mi JOUNG
  • Publication number: 20120245225
    Abstract: The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
    Type: Application
    Filed: June 5, 2012
    Publication date: September 27, 2012
    Applicants: DAEWOONG PHARMACEUTICAL CO., LTD, MEDIFRON DBT CO., LTD.
    Inventors: Dong Wook KANG, Jee Woo LEE, Young Ho KIM, Hee KIM, Hee Jin HA, Eun Joo NAM, Chan Mi JOUNG
  • Patent number: 8263649
    Abstract: The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
    Type: Grant
    Filed: October 2, 2007
    Date of Patent: September 11, 2012
    Assignee: Medifron DBT Co., Ltd.
    Inventors: Dong Wook Kang, Jee Woo Lee, Young Ho Kim, Hee Kim, Hee Jin Ha, Eun Joo Nam, Chan Mi Joung