Abstract: The invention provides artificial chromosome constructs containing foreign nucleic acid sequences, such as viral nucleic acid sequences, and methods of using these artificial chromosome constructs for therapy and recombinant virus production.
Type:
Grant
Filed:
August 3, 2001
Date of Patent:
November 4, 2003
Assignee:
MediGene, Inc.
Inventors:
Brian Horsburgh, Dong Qiang, Francis Tufaro, Jeffery Ostrove
Abstract: The invention provides artificial chromosome constructs containing foreign nucleic acid sequences, such as viral nucleic acid sequences, and methods of using these artificial chromosome constructs for therapy and recombinant virus production.
Type:
Grant
Filed:
February 26, 1998
Date of Patent:
August 21, 2001
Assignee:
MediGene, Inc.
Inventors:
Brian Horsburgh, Dong Qiang, Francis Tufaro, Jeffrey Ostrove