Patents Assigned to MedImmune Ltd.
  • Nucleic acids coding for antibodies against human IL-21 receptor and uses therefor
    Patent number: 8143385
    Abstract: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-21 receptor (IL-21R). The antibodies can act as antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, transplant rejection, cancer, and other immune system disorders.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: March 27, 2012
    Assignees: Wyeth LLC, MedImmune Ltd.
    Inventors: Viia Valge-Archer, Andrew James Williams, Deborah A. Young, Matthew J. Whitters, Mary Collins, Joann Witek