Abstract: A substance transfer device for topical or transdermal drug delivery to a living body or collection of fluids from a living body, comprises a layer of skin or wound surface compatible adhesive having a surface for contacting the body, and channels therethrough which provide liquid communication with depots of drug or collection means. These channels form discrete, exposed areas of drug composition or drug delivery means, surrounded by the adhesive. The drug contained in the device does not need to pass through the layer of adhesive before contacting the underlying skin. In one arrangement, particularly suitable for delivery of macromolecular drugs, the channels extend through the entire thickness of the adhesive layer, and communicate with reservoirs of drug.

Abstract: The invention disclosed is a hydrogel-forming wound dressing or skin coating material suitable for household and veterinary use, consisting substantially entirely of wound-compatible and skin-compatible ingredients and comprising a first hydrophilic polymer, selected from polymers or copolymers of acrylic acid, polymers or copolymers of methacrylic acid, polymers or copolymers of itaconic acid, polymers or copolymers of maleic acid and polymers or copolymers of 3-butene-1,2,3-tricarboxylic acid, or combinations thereof, a second hydrophilic polymer which is capable of interacting with the first polymer to produce, upon drying, a hydrogel of improved water resistance and film forming properties relative to the first polymer alone and water. This material is film forming and substantially transparent but capable of being made opaque.

Abstract: A device for unblocking intubation tubes in intubated patients and tracheotomy cannulas in tracheotomized patients comprises two elements which are introduced into the intubation tube or tracheotomy cannula by their distal end, namely a flexible rod (1) rounded at its distal end (2) provided with a collapsible system (3) near its distal end, and provided with a projection (5) at the other end to permit manipulation, and a flexible tube (4) provide with a reference stop (6) at its proximal end, into which the rod (1) is inserted and in which it can slide. The collapsible system (3) is collapsed in the flexible tube (4) and the sliding of the central rod (1) inside the flexible tube (4) after the introduction of device into the intubation tube or into the tracheotomy cannula releases the collapsible system (3), which sweeps the tube and the tracheotomy cannula as the device is withdrawn. This device may be sterile and disposable. Its use is recommended one to four times daily.

Abstract: The invention disclosed is a hydrogel-forming wound dressing or skin coating material suitable for household and veterinary use, consisting substantially entirely of wound-compatible and skin-compatible ingredients and comprising a first hydrophilic polymer, selected from polymers or copolymers of acrylic acid, polymers or copolymers of methacrylic acid, polymers or copolymers of itaconic acid, polymers or copolymers of maleic acid and polymers or copolymers of 3-butene-1,2,3-tricarboxylic acid, or combinations thereof, a second hydrophilic polymer which is capable of interacting with the first polymer to produce, upon drying, a hydrogen of improved water resistance and film forming properties relative to the first polymer alone and water. This material is film forming and substantially transparent but capable of being made opaque.