Abstract: A closed pouch for infusion liquid is made from a continuously extruded plastics hose by providing transverse seals and cutting the hose in said seals, and an assembly of two necks and a filling hose connection is secured to the outer wall of each pouch, said wall being pierced when liquid is to be extracted from or supplied to the pouch through one of said necks. Such an assembly is made from plastics as a unitary structure together with closing caps for the necks and a common flange to be secured to said wall. One neck is provided, at the flange side, with an enlarged bore terminating in a shoulder which is substantially parallel to the flange, and a pierceable sealing pad is inserted from the flange side into said enlarged bore, the latter being eventually closed by the pouch wall.