Patents Assigned to Medivance Incorporated
  • Patent number: 11446176
    Abstract: A system and method are provided, the system including a monitoring device to monitor sensory data of a patient and to provide a sensory data response thereto, and a control unit configurable to cool or warm circulated fluid through at least one contact pad for thermal exchange with the patient. The monitoring device can be configured to monitor a patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. A processor can be provided to process the monitoring signal and provide an output employable by medical personnel. The processor can be programmed to control automatically a temperature of the circulated fluid to cool or warm the patient in different treatment phases in accordance with a predetermined protocol, and process the sensory data signal to provide an output signal indicative of a sensory measurement.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: September 20, 2022
    Assignee: Medivance Incorporated
    Inventors: Marc E. Voorhees, Gary A. Carson, Gary Gruszecki
  • Patent number: 11234859
    Abstract: An improved medical pad for contact thermal exchange with a patient includes a fluid circulation layer for containing a thermal exchange fluid circulatable therethrough, a first port and a second port for circulating the thermal exchange fluid in to and out of the fluid circulation layer, and a hydrogel layer interconnected to and extending across one side of the fluid circulation layer to define an adhesive surface for adherence to a patient's skin. The hydrogel layer comprises an ultra violet light-cured composition that includes a cross-linking copolymer in an amount of between about 15% to 30% by weight of the composition, water in an amount of between about 15% to 40% by weight of the composition, and glycerol in an amount of between about 25% to 35% by weight of the composition. The hydrogel layer is provided to have a thermal conductivity of at least about 1.9 cal/hr-cm-° C.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: February 1, 2022
    Assignee: Medivance Incorporated
    Inventors: Marc E. Voorhees, Michael R. Hoglund, Keir David Hart
  • Patent number: 10729578
    Abstract: A patient temperature control system and method are provided for automated temperature control according to a programmed protocol. In one aspect, at least one programmed protocol may be established for each of a plurality of patient thermal therapy phases. In turn, the temperature of a thermal exchange medium may be controlled, based at least in part, upon the programmed protocol, during each of the phases. In another aspect, a plurality of programmed protocols may be established, wherein a selected one of the protocols (e.g. selected by a user at a user interface) may be utilized for automated temperature control during patient thermal therapy. The protocol(s) may include a target patient temperature and/or a set duration for one or more of the phase of thermal therapy. Further, the protocol(s) may be user-definable and modifiable during therapy.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: August 4, 2020
    Assignee: Medivance Incorporated
    Inventors: Gary A. Carson, Gary Gruszecki, Robert Proctor
  • Patent number: 10588779
    Abstract: A system and method are provided that employ a monitoring device to monitor at least one patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. In turn, an output (e.g. a visual and/or auditory output) may be provided to a user indicative of at least one measure of patient response to the change in temperature. Alternatively or additionally, a processor may be provided to process the monitoring signal and provide an output employable by medical personnel to control a patient shivering response to the patient temperature change. Such information may comprise information regarding one or more anti-shivering medicament(s), e.g. corresponding dosage and/or frequency information for use by medical personnel in the administration of the anti-shivering medicament.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: March 17, 2020
    Assignee: Medivance Incorporated
    Inventors: Marc Voorhees, Gary A. Carson, Gary Gruszecki
  • Patent number: 10441707
    Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: October 15, 2019
    Assignee: MEDIVANCE INCORPORATED
    Inventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
  • Patent number: 10258501
    Abstract: A sorption-based, adhesive contact apparatus and method for contact cooling a patient via conductive thermal exchange are described. The apparatus includes a pad, having a fluid containing layer and adhesive contact surface, and a sorption-based device, fluidly interconnectable to the fluid containing layer, for vaporizing fluid contained in the fluid containing layer and for sorping the vaporized fluid. The fluid vaporization and the vapor sorption cools the adhesive contact surface of the pad. A port control member may selectively establish fluid interconnection between the fluid containing layer and sorption-based device. An internal pressure of the sorption-based device may be established lower than an internal pressure of the fluid-containing layer prior to fluid interconnection therebetween. A fluid retention member and path defining members may be included to facilitate vaporization, vapor diffusion and vapor sorption, thereby enhancing uniform cooling.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: April 16, 2019
    Assignee: Medivance Incorporated
    Inventor: Gary A. Carson
  • Patent number: 10123902
    Abstract: A patient temperature control system and method are provided for automated temperature control according to a programmed protocol. In one aspect, at least one programmed protocol may be established for each of a plurality of patient thermal therapy phases. In turn, the temperature of a thermal exchange medium may be controlled, based at least in part, upon the programmed protocol, during each of the phases. In another aspect, a plurality of programmed protocols may be established, wherein a selected one of the protocols (e.g. selected by a user at a user interface) may be utilized for automated temperature control during patient thermal therapy. The protocol(s) may include a target patient temperature and/or a set duration for one or more of the phase of thermal therapy. Further, the protocol(s) may be user-definable and modifiable during therapy.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: November 13, 2018
    Assignee: Medivance Incorporated
    Inventors: Gary A. Carson, Gary Gruszecki, Robert Proctor
  • Patent number: 9763823
    Abstract: A system and method are provided that employ a monitoring device to monitor at least one patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. In turn, an output (e.g. a visual and/or auditory output) may be provided to a user indicative of at least one measure of patient response to the change in temperature. Alternatively or additionally, a processor may be provided to process the monitoring signal and provide an output employable by medical personnel to control a patient shivering response to the patient temperature change. Such information may comprise information regarding one or more anti-shivering medicament(s), e.g. corresponding dosage and/or frequency information for use by medical personnel in the administration of the anti-shivering medicament.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: September 19, 2017
    Assignee: Medivance Incorporated
    Inventors: Marc Voorhees, Gary A. Carson, Gary Gruszecki
  • Patent number: 9687386
    Abstract: A medical pad has multiple layers. A first layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the first layer. A second layer of the medical pad is interconnected to a second side of the first layer, opposite to the first side of the first layer. The second layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. The medical pad is operable for thermal exchange between the second thermal-exchange fluid and the patient.
    Type: Grant
    Filed: September 12, 2011
    Date of Patent: June 27, 2017
    Assignee: Medivance Incorporated
    Inventor: Gary A. Carson
  • Patent number: 9622907
    Abstract: A medical pad has multiple layers. A first layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the first layer. A second layer of the medical pad is interconnected to a second side of the first layer, opposite to the first side of the first layer. The second layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. The medical pad is operable for thermal exchange between the second thermal-exchange fluid and the patient.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: April 18, 2017
    Assignee: Medivance Incorporated
    Inventors: Gary A. Carson, Michael R. Hoglund, Marc E. Voorhees
  • Patent number: 9566185
    Abstract: A patient temperature control system and method are provided for automated temperature control according to a programmed protocol. In one aspect, at least one programmed protocol may be established for each of a plurality of patient thermal therapy phases. In turn, the temperature of a thermal exchange medium may be controlled, based at least in part, upon the programmed protocol, during each of the phases. In another aspect, a plurality of programmed protocols may be established, wherein a selected one of the protocols (e.g. selected by a user at a user interface) may be utilized for automated temperature control during patient thermal therapy. The protocol(s) may include a target patient temperature and/or a set duration for one or more of the phase of thermal therapy. Further, the protocol(s) may be user-definable and modifiable during therapy.
    Type: Grant
    Filed: October 13, 2008
    Date of Patent: February 14, 2017
    Assignee: Medivance Incorporated
    Inventors: Gary A. Carson, Gary Gruszecki, Robert Proctor
  • Patent number: 9333112
    Abstract: A sorption-based, adhesive contact apparatus and method for contact cooling a patient via conductive thermal exchange are described. The apparatus includes a pad, having a fluid containing layer and adhesive contact surface, and a sorption-based device, fluidly interconnectable to the fluid containing layer, for vaporizing fluid contained in the fluid containing layer and for sorping the vaporized fluid. The fluid vaporization and the vapor sorption cools the adhesive contact surface of the pad. A port control member may selectively establish fluid interconnection between the fluid containing layer and sorption-based device. An internal pressure of the sorption-based device may be established lower than an internal pressure of the fluid-containing layer prior to fluid interconnection therebetween. A fluid retention member and path defining members may be included to facilitate vaporization, vapor diffusion and vapor sorption, thereby enhancing uniform cooling.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: May 10, 2016
    Assignee: Medivance Incorporated
    Inventor: Gary A. Carson
  • Publication number: 20140214138
    Abstract: A medical pad having a dual layer portion including a fluid circulation and containment layers and a single layer portion including the fluid circulation layer. The fluid circulation layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the fluid circulation layer. A fluid containment layer of the medical pad is interconnected to a portion of second side of the fluid circulation layer, opposite to the first side of the fluid circulation layer. The fluid containment layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. Portions of the fluid circulation layer that extend beyond the fluid containment layer define flaps that provide additional area for fluid circulation.
    Type: Application
    Filed: August 16, 2013
    Publication date: July 31, 2014
    Applicant: Medivance Incorporated
    Inventors: Marc E. Voorhees, Owen Mandry
  • Patent number: 8491644
    Abstract: A portable patient cooling apparatus is provided that includes a self-contained refrigerator and on-board power storage supply for stand alone operation. The apparatus is interconnectable to one or more heat exchange devices (e.g. patient contact pads or intravascular catheters) through which a cooled fluid may be circulated for patient cooling. Such fluid may be liquid contained within a reservoir comprising the apparatus during periods of non-use. The apparatus preferably defines a total volume of less than about 0.04 m3, while having a total weight of less than about 15 kg to yield a total circulated fluid cooling capacity of at least 200 watts.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: July 23, 2013
    Assignee: Medivance Incorporated
    Inventors: Gary Carson, Gary Gruzecki, Steve Whitehead
  • Publication number: 20130116760
    Abstract: A medical pad has multiple layers. A first layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the first layer. A second layer of the medical pad is interconnected to a second side of the first layer, opposite to the first side of the first layer. The second layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. The medical pad is operable for thermal exchange between the second thermal-exchange fluid and the patient.
    Type: Application
    Filed: October 26, 2012
    Publication date: May 9, 2013
    Applicant: Medivance Incorporated
    Inventor: Medivance Incorporated
  • Publication number: 20120065715
    Abstract: A medical pad has multiple layers. A first layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the first layer. A second layer of the medical pad is interconnected to a second side of the first layer, opposite to the first side of the first layer. The second layer encloses a second thermal-exchange fluid that may have a freezing point of 0° C. or less. The medical pad is operable for thermal exchange between the second thermal-exchange fluid and the patient.
    Type: Application
    Filed: September 12, 2011
    Publication date: March 15, 2012
    Applicant: Medivance Incorporated
    Inventor: Gary A. Carson
  • Patent number: 8047010
    Abstract: A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: November 1, 2011
    Assignee: Medivance Incorporated
    Inventors: Gary A. Carson, Marc E. Voorhees
  • Publication number: 20090299287
    Abstract: A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.
    Type: Application
    Filed: May 18, 2009
    Publication date: December 3, 2009
    Applicant: Medivance Incorporated
    Inventors: Gary A. Carson, Marc E. Voorhees
  • Publication number: 20090131835
    Abstract: A system and method are provided that employ a monitoring device to monitor at least one patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. In turn, an output (e.g. a visual and/or auditory output) may be provided to a user indicative of at least one measure of patient response to the change in temperature. Alternatively or additionally, a processor may be provided to process the monitoring signal and provide an output employable by medical personnel to control a patient shivering response to the patient temperature change. Such information may comprise information regarding one or more anti-shivering medicament(s), e.g. corresponding dosage and/or frequency information for use by medical personnel in the administration of the anti-shivering medicament.
    Type: Application
    Filed: November 17, 2008
    Publication date: May 21, 2009
    Applicant: MEDIVANCE INCORPORATED
    Inventors: Marc Voorhees, Gary A. Carson, Gary Gruszecki
  • Patent number: D685916
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: July 9, 2013
    Assignee: Medivance Incorporated
    Inventor: Michael R. Hoglund