Abstract: The patent discloses the use of Hepatocellular Carcinoma Related Protein 1 (HCRP1) as a marker for the efficiency of an anti-EGFR antibody treatment of a tumour patient. If a tumour biopsy sample of the tumour patient reveals an HCRP1 protein or mRNA amount equal to or above the amount in normal, non-tumour tissue, then the tumour patient is eligible for the treatment with an anti-EGFR antibody.

Abstract: The invention relates to a bone screw set for fixing two bone fragments, especially for treating a scaphoid bone fracture or a scaphoid bone pesudoarthrosis, comprising a first bone screw (1) and at least one second bone screw (2). The first bone screw (1) is preferably embodied as a compression screw, and the first and second bone screws (1, 2) comprise interacting engagement means for fixing the second bone screw (2) in a position, in relation to the first bone screw (1), wherein at least part of the second bone screw protrudes from the cross-section of the first bone screw (1).

Abstract: The invention relates to a method for carrying out a percrestale sinus lift, wherein a bore channel is created with the aid of a boring, milling and/or hammering method, the Schneider membrane is lifted from the jaw bone using a flowable medium that is supplied via the opened bore channel, bone replacement material is introduced, a supply line is introduced into the bore channel prior to introducing the flowable liquid and is sealingly fixed in a detachable manner to the bore channel or onto the edge thereof and the flowable medium in introduced through the supply line. The invention also relates to a surgical instrument (1) for introducing a flowable medium for lifting the Schneider membrane from the jaw bone whilst carrying out a percrestale sinus lift.

Abstract: Use of human erythropoietin or a derivative of erythropoietin having the biological activity of human erythropoietin of increasing the expression of frataxin for the production of a pharmaceutical preparation for the treatment of Friedreich's ataxia or for the treatment or prevention of a disease associated with Friedreich's ataxia.

Abstract: Optical coherence tomograph (OCT) probe device (1) comprising an endoscope (6) which is adapted to be coupled to a light source (2) and has a distal tip portion (6.2), the tip portion (6.2) including focussing lens means (11) and a window (5) for directing light to a subject (7) to be scanned, and for receiving light scattered at the subject (7), to send the scattered light back through the endoscope (6) so that it may be applied to a detector (3) together with reference light, said OCT probe device (1) comprising a beam splitter (13; 17) to separate said reference light from the remaining light, as well as a reference light reflector (4; 20) for reflecting the reference light back so that it is composed to the light returned from the subject (7); the beam splitter (13; 17) and the reference light reflector (4; 20) are located in the tip portion (6.2) of the endoscope means (6) behind the focussing lens means (11) through which the composed light is sent back.