Patents Assigned to Medtronic CoreValve LLC
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Publication number: 20140121765Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchors may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. A radial restraint, comprising a wire, thread or cuff, may be used to ensure expansion does not exceed the preset diameter. The valve support may optionally comprise a drug elution component. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place.Type: ApplicationFiled: October 28, 2013Publication date: May 1, 2014Applicant: Medtronic Corevalve LLCInventors: Jacques SEGUIN, Georg Bortlein
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Publication number: 20140100653Abstract: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.Type: ApplicationFiled: December 9, 2013Publication date: April 10, 2014Applicant: Medtronic Corevalve LLCInventors: Padraig SAVAGE, Gianfranco Pellegrini, Finn Rinne, Matthew Rust, Michael Krivoruchko
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Publication number: 20140088693Abstract: An apparatus for treating a heart valve apparatus includes at least two anchoring elements designed to be anchored at the annulus and/or heart wall of the valve to be treated. Each anchoring element has a support surface. At least one linking element includes a central branch and two curved side branches, one of which is designed to be engaged on the support surface of an anchoring element, while the other is designed to be engaged on the support surface of another anchoring element, the linking element then being designed to be pivoted to a position such that the anchoring elements interconnect and in which the ends of the central branch are located in the vicinity of the support surfaces.Type: ApplicationFiled: November 26, 2013Publication date: March 27, 2014Applicant: Medtronic Corevalve LLCInventors: Jacques Seguin, Bruno Lecointe, Remi Gerriet
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Patent number: 8628570Abstract: A prosthetic valve assembly can include a radially expandable stent. The stent can include a first expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, a second expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen. The stent can also include a plurality of rods extending between the first annular portion and the second annular portion. The prosthetic valve assembly can further include an implantable prosthetic valve mounted to the stent such that the valve is between the first annular portion and the second annular portion. The prosthetic valve assembly is configured to be delivered by catheterization.Type: GrantFiled: August 18, 2011Date of Patent: January 14, 2014Assignee: Medtronic CoreValve LLCInventor: Jacques Seguin
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Publication number: 20140005774Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: ApplicationFiled: January 20, 2011Publication date: January 2, 2014Applicant: Medtronic CoreValve LLCInventors: Jacques SEGUIN, Georg Börtlein
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Patent number: 8603159Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: GrantFiled: December 11, 2009Date of Patent: December 10, 2013Assignee: Medtronic Corevalve, LLCInventors: Jacques Seguin, Georg Bortlein
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Patent number: 8579966Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia.Type: GrantFiled: February 4, 2004Date of Patent: November 12, 2013Assignee: Medtronic CoreValve LLCInventors: Jacques Seguin, Georg Börtlein
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Publication number: 20130035758Abstract: An apparatus for treating a heart valve apparatus includes at least two anchoring elements designed to be anchored at the annulus and/or heart wall of the valve to be treated. Each anchoring element has a support surface. At least one linking element includes a central branch and two curved side branches, one of which is designed to be engaged on the support surface of an anchoring element, while the other is designed to be engaged on the support surface of another anchoring element, the linking element then being designed to be pivoted to a position such that the anchoring elements interconnect and in which the ends of the central branch are located in the vicinity of the support surfaces.Type: ApplicationFiled: August 10, 2012Publication date: February 7, 2013Applicant: Medtronic Corevalve LLCInventors: Jacques SEGUIN, Bruno LECOINTE, Remi GERRIET
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Publication number: 20120143316Abstract: A prosthetic valve comprises a valve assembly having a base, a plurality of leaflets, and commissures. The valve also comprises a support stent having a plurality of expandable cells and a plurality of longitudinal struts. The support stent is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the prosthetic valve is positioned in situ. The support stent supports the base. The commissures of the valve assembly are secured at the longitudinal struts and adjacent one or more of the expandable cells. The longitudinal struts of the support stent further comprise a plurality of holes, and the plurality of leaflets are secured to the longitudinal struts via threads passing through the plurality of holes.Type: ApplicationFiled: December 7, 2011Publication date: June 7, 2012Applicant: Medtronic CoreValve LLCInventors: Jacques Seguin, Georg Börtlein
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Publication number: 20120083878Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchors may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. A radial restraint, comprising a wire, thread or cuff, may be used to ensure expansion does not exceed the preset diameter.Type: ApplicationFiled: September 23, 2011Publication date: April 5, 2012Applicant: Medtronic CoreValve LLCInventors: Jacques Sequin, Georg Börtlein
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Publication number: 20110301692Abstract: A prosthetic valve assembly can include a radially expandable stent. The stent can includea first expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, a second expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen. The stent can also include a plurality of rods extending between the first annular portion and the second annular portion. The prosthetic valve assembly can further include an implantable prosthetic valve mounted to the stent such that the valve is between the first annular portion and the second annular portion. The prosthetic valve assembly is configured to be delivered by catheterization.Type: ApplicationFiled: August 18, 2011Publication date: December 8, 2011Applicant: Medtronic CoreValve LLCInventor: Jacques SEGUIN
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Patent number: 8016877Abstract: A method for deploying a prosthetic valve assembly is provided. The prosthetic valve assembly replaces a deficient native valve and comprises a replacement valve supported on an expandable valve support. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary oslia. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: GrantFiled: June 29, 2009Date of Patent: September 13, 2011Assignee: Medtronic Corevalve LLCInventors: Jacques Seguin, Georg Bortlein
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Publication number: 20110213461Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: ApplicationFiled: May 10, 2011Publication date: September 1, 2011Applicant: Medtronic CoreValve LLCInventors: Jacques SEGUIN, Georg BÖRTLEIN
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Patent number: 8002826Abstract: The present invention is an assembly comprising a prosthetic valve to be implanted; a radially expandable stent comprising at least one zone intended to be expanded to allow the stent, in the expanded state, to bear against the wall of the body duct to be fitted with the valve, this bearing making it possible to immobilize this stent with respect to this wall; and means for mounting the valve with respect to the stent, making it possible to connect the valve to the stent in such a way that the placement of the stent allows the valve to be mounted in the body duct, and expansion means such as a balloon catheter being provided to trigger expansion of the stent at the implantation site. According to the invention, the valve and the stent are designed in such a way that, at the moment when the stent is expanded, the valve is situated outside the zone or zones of the stent that are subjected to said expansion means.Type: GrantFiled: October 14, 2009Date of Patent: August 23, 2011Assignee: Medtronic Corevalve LLCInventor: Jacques Seguin
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Publication number: 20110172765Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.Type: ApplicationFiled: March 25, 2011Publication date: July 14, 2011Applicant: Medtronic CoreValve LLCInventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
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Publication number: 20110125257Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: ApplicationFiled: January 20, 2011Publication date: May 26, 2011Applicant: Medtronic CoreValve LLCInventors: Jacques SEGUIN, Georg Börtlein
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Patent number: 7914569Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.Type: GrantFiled: May 13, 2005Date of Patent: March 29, 2011Assignee: Medtronics CoreValve LLCInventors: Than Nguyen, Hung Nguyen, Mykim Nguyen, Stanley Komatsu, Robrecht Michiels
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Patent number: 7892281Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.Type: GrantFiled: January 5, 2009Date of Patent: February 22, 2011Assignee: Medtronic CoreValve LLCInventors: Jacques Seguin, Georg Börtlein
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Publication number: 20100292785Abstract: This implant (1) is formed by a helically wound wire (2). According to the invention, it has dimensions such that it is able to be screwed into the wall of the annulus (103) and/or into the cardiac wall (101) adjoining this annulus (103) such that a portion of said annulus (103) and/or of said wall (101) is located in the perimeter of the implant (1); and it comprises at least one first coil able, during said screwing of the implant (1), to insert itself into said wall while having a first dimension and at least one second coil having a second dimension, or adopting this second dimension after implantation, said second dimension being smaller than the first dimension such that the implant (1), once inserted, enables contraction of said wall portion located in the perimeter of this implant (1).Type: ApplicationFiled: April 14, 2008Publication date: November 18, 2010Applicant: Medtronic Corevalve LLCInventors: Jacques Seguin, Than Nguyen, Bruno Lecointe
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Publication number: 20100036485Abstract: The present invention is an assembly comprising a prosthetic valve to be implanted; a radially expandable stent comprising at least one zone intended to be expanded to allow the stent, in the expanded state, to bear against the wall of the body duct to be fitted with the valve, this bearing making it possible to immobilize this stent with respect to this wall; and means for mounting the valve with respect to the stent, making it possible to connect the valve to the stent in such a way that the placement of the stent allows the valve to be mounted in the body duct, and expansion means such as a balloon catheter being provided to trigger expansion of the stent at the implantation site. According to the invention, the valve and the stent are designed in such a way that, at the moment when the stent is expanded, the valve is situated outside the zone or zones of the stent that are subjected to said expansion means.Type: ApplicationFiled: October 14, 2009Publication date: February 11, 2010Applicant: Medtronic CoreValve LLCInventor: Jacques SEGUIN