Patents Assigned to Medtronic Cryocath LP
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Publication number: 20130197496Abstract: A method and device for treating tissue with temperature-sensitizing adjuvants to enhance the effects of ablation therapy. The method may comprise identifying tissue to receive ablation therapy, treating the tissue with a temperature-sensitizing agent, and activating an ablation therapy device proximate the treated tissue. The device may comprise a cryo-sensitizing adjuvant operable in association with a cryotherapy device, the cryo-sensitizing adjuvant enhancing the effectiveness of tissue destruction upon application of temperatures below 0° C.Type: ApplicationFiled: July 23, 2012Publication date: August 1, 2013Applicant: MEDTRONIC CRYOCATH LPInventors: Claudia LUECKGE, Ethel RUBIN
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Publication number: 20130197497Abstract: A medical device including a catheter body defining a proximal portion and a distal portion. An expandable element is included defining a proximal end and a distal end, the proximal end being coupled to the distal portion of the catheter body. A tip element coupled to the distal end of the expandable element is included, the tip element including a shaft slideably receivable within a portion of the catheter body. A tensioning element coupled to the shaft and disposed within the expandable element is included, the tensioning element being engageable with the distal end of the catheter body and biasing the expandable element toward a pre-determined longitudinal position. An electrode array defining a substantially closed loop affixed to and extending from the tip element is also included.Type: ApplicationFiled: January 27, 2012Publication date: August 1, 2013Applicant: MEDTRONIC CRYOCATH LPInventors: Dan WITTENBERGER, Claudia LUECKGE, Réal STE-MARIE
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Publication number: 20130172866Abstract: A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.Type: ApplicationFiled: January 25, 2013Publication date: July 4, 2013Applicant: MEDTRONIC CRYOCATH LPInventor: MEDTRONIC CRYOCATH LP
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Patent number: 8475440Abstract: The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body having a substantially fixed diameter, a proximal end and a distal end; a first lumen for permitting passage of a cooling fluid from the proximal end to the distal end; a second lumen permitting return of the cooling fluid from the distal end to the proximal end; and an ablation element expandable from a first diameter that is substantially the same as the diameter of the catheter body to a second diameter that is at least twice the diameter of the catheter body, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more balloon and/or a flexible element that is deformed by moving the distal end of the catheter toward the proximal end of the catheter.Type: GrantFiled: December 10, 2007Date of Patent: July 2, 2013Assignee: Medtronic Cryocath LPInventors: Marwan Abboud, Fredric L. Milder, George Klein
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Publication number: 20130165927Abstract: A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation tool is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.Type: ApplicationFiled: February 20, 2013Publication date: June 27, 2013Applicant: MEDTRONIC CRYOCATH LPInventor: Medtronic Cryocath LP
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Patent number: 8454587Abstract: A coolant system for a cryoablation or treatment probe that includes a compressor and condenser having a low pressure inlet side and a high pressure outlet side, wherein the outlet side passes through a heat exchanger and is cooled by the inlet side and conditioned for injection to a catheter inlet. A vacuum return system connectable to the catheter outlet draws thermally expended coolant from the catheter and returns it to the low pressure inlet side. A motorized pressure regulator between the heat exchanger and the catheter inlet determines the pressure of coolant passing into the catheter, regulating the cooling rate for a selected mapping or ablation regimen. A coolant reservoir feeds into the low pressure inlet side and receives a return flow of excess fluid from a branch off the outlet side of the compressor.Type: GrantFiled: November 30, 2007Date of Patent: June 4, 2013Assignee: Medtronic Cryocath LPInventors: Jean-Pierre Lalonde, Marwan Abboud
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Publication number: 20130110100Abstract: Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.Type: ApplicationFiled: March 1, 2012Publication date: May 2, 2013Applicant: MEDTRONIC CRYOCATH LPInventors: Regina E. GROVES, Jean-Pierre LALONDE, Timothy G. LASKE, Claudia LUECKGE, Dan WITTENBERGER, Ramin SABBAGHE-KERMANI, Mahmoud KABIR-SERAJ
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Publication number: 20130104993Abstract: Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.Type: ApplicationFiled: March 1, 2012Publication date: May 2, 2013Applicant: MEDTRONIC CRYOCATH LPInventors: Regina E. GROVES, Jean-Pierre LALONDE, Timothy G. LASKE, Claudia LUECKGE, Dan WITTENBERGER, Ramin SABBAGHE-KERMANI, Mahmoud KABIR-SERAJ
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Publication number: 20130110098Abstract: An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.Type: ApplicationFiled: October 27, 2011Publication date: May 2, 2013Applicant: Medtronic CryoCath LPInventor: Jean-Pierre Lalonde
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Publication number: 20130109994Abstract: Systems and methods for monitoring phrenic nerve function of a patient are disclosed, including, including establishing a diaphragmatic movement value threshold; positioning a diaphragmatic movement sensor on an external surface of an abdomen of the patient; applying a treatment regimen to a tissue region in proximity to the phrenic nerve; measuring a diaphragmatic movement value with the diaphragmatic movement sensor; comparing the measured diaphragmatic movement value to the established diaphragmatic movement value threshold; and generating an alert in response to the comparison.Type: ApplicationFiled: October 27, 2011Publication date: May 2, 2013Applicant: MEDTRONIC CRYOCATH LPInventors: Yong K. CHO, Scott A. RANSOM, Xusheng ZHANG
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Publication number: 20130110148Abstract: A cryogenic medical system and method of use thereof for transseptal puncturing is disclosed, including a medical device having an elongate body with a fluid flow path therein, a thermally-transmissive region coupled to the elongate body in thermal communication with the fluid flow path, and a puncturing element movably coupled to the elongate body; and a cryogenic coolant source in fluid communication with the fluid flow path. The medical device may alternatively include an elongate body, a thermally-transmissive region coupled to the elongate body, a thermo-electric cooler in thermal communication with the thermally-transmissive region, and a puncturing element movably coupled to the elongate body.Type: ApplicationFiled: October 26, 2011Publication date: May 2, 2013Applicant: MEDTRONIC CRYOCATH LPInventor: Jean-Pierre LALONDE
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Publication number: 20130110099Abstract: Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.Type: ApplicationFiled: November 21, 2011Publication date: May 2, 2013Applicant: MEDTRONIC CRYOCATH LPInventors: Regina E. GROVES, Jean-Pierre LALONDE, Timothy G. LASKE, Claudia LUECKGE, Dan WITTENBERGER, Ramin SABBAGHE-KERMANI, Mahmoud Kabir SERAJ
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Patent number: 8425456Abstract: A catheter includes a first expandable membrane having a first pressurization limit and a second expandable membrane, having a second pressurization limit, wherein the second pressurization limit is greater than the first pressurization limit, the first expandable membrane defines a cooling chamber, the second expandable membrane being disposed around the first expandable membrane to define an junction therebetween. The catheter includes a coolant injection lumen in fluid communication with the at least one fluid inlet port and the cooling chamber, and a primary coolant return lumen in fluid communication with the at least one fluid outlet port and the cooling chamber. The coolant injection tube, the cooling chamber, and the primary coolant return lumen define a first fluid pathway. The catheter further includes a secondary coolant return lumen in fluid communication with the at least one fluid outlet port and the junction. The junction and the secondary coolant return lumen define a second fluid pathway.Type: GrantFiled: April 27, 2010Date of Patent: April 23, 2013Assignee: Medtronic Cryocath LPInventors: Teresa Ann Mihalik, Jean-Luc Pageard, John W. Lehmann
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Patent number: 8398632Abstract: A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation tool is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.Type: GrantFiled: March 14, 2006Date of Patent: March 19, 2013Assignee: Medtronic Cryocath LPInventors: Daniel Nahon, Sean Carroll, Dan Wittenberger, Cristian Petre, Allan Skanes, Alan H. Menkis, Réal Ste-Marie
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Patent number: 8382747Abstract: A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.Type: GrantFiled: October 18, 2007Date of Patent: February 26, 2013Assignee: Medtronic Cryocath LPInventors: Marwan Abboud, Rachid Mahrouche, Chadi Harmouche, Teresa Mihalik, Gilles Desrochers
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Patent number: 8361059Abstract: A cryogenic medical system includes a medical device and a console connectable to the medical device at a connection point. The console controls the temperature of the medical device. The console includes a first cooling system directing coolant to the medical device at a first temperature along a coolant supply line and a second cooling system chilling the coolant within the coolant supply line to a temperature below the first temperature before the coolant reaches the connection point.Type: GrantFiled: October 13, 2006Date of Patent: January 29, 2013Assignee: Medtronic Cryocath LPInventors: Marwan Abboud, Rachid Mahrouche, Jean-Pierre Lalonde, Dan Wittenberger
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Publication number: 20130018369Abstract: A method of treating a target tissue including positioning a treatment element of a medical device adjacent the target tissue; setting a first target temperature of the treatment element; operating the treatment element to reach the first target temperature; thermally treating the target tissue with the treatment element; monitoring a physiological parameter; setting a second target temperature of the treatment element based on the monitored physiological parameter; and operating the treatment element to reach the second target temperature.Type: ApplicationFiled: July 13, 2011Publication date: January 17, 2013Applicant: MEDTRONIC CRYOCATH LPInventor: Teresa Ann MIHALIK
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Patent number: 8298217Abstract: An elongated catheter device with a distal balloon assembly is adapted for endovascular insertion. Coolant injected through the device may, in different embodiments, directly cool tissue contacting the balloon, or may cool a separate internal chamber. Plural balloons may be provided, wherein a secondary outer balloon surrounds a primary inner balloon, the primary balloon being filled with coolant and acting as the cooling chamber, the secondary balloon being coupled to a vacuum return lumen to serve as a robust leak containment device and thermal insulator around the cooling chamber. One or more sensors may be disposed between the balloons or the vacuum return lumen, to detect leaks and control the flow of fluid through the device. Examples of sensors include pressure and temperature sensors, optical sensors, magnetic flow switches and flow meters.Type: GrantFiled: March 25, 2009Date of Patent: October 30, 2012Assignee: Medtronic Cryocath LPInventors: Miriam Lane, Marwan Abboud, Rachid Mahrouche, Teresa Ann Mihalik
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Patent number: 8298219Abstract: A method of cryogenically treating a tissue region is provided, including positioning a treatment region of a medical device proximate the tissue region; transferring coolant in a substantially liquid phase from a coolant reservoir to a subcooler; transitioning the coolant from the liquid phase into a supercritical state; transferring the supercritical coolant to the treatment region; changing the coolant from the supercritical state to at least one of a liquid phase and a gaseous phase at the treatment region; ablating the tissue region; and evacuating coolant from the treatment region of the medical device.Type: GrantFiled: September 2, 2009Date of Patent: October 30, 2012Assignee: Medtronic Cryocath LPInventor: Jean-Pierre LaLonde
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Patent number: 8297108Abstract: The present invention provides a surgical device including an elongate body defining a fluid flow path therethrough. An expandable element may be coupled to the elongate body and placed in fluid communication with the fluid flow path. Moreover, the surgical device may include a first leak detection element at least partially surrounding a portion of the expandable element, and a second leak detection element may be provided in fluid communication with the fluid flow path. In addition, a console may be provided, where the console may be in communication with the first and second leak detection elements. Further, a supply of cryogenic fluid as well as a vacuum source may be provided in fluid communication with the fluid flow path.Type: GrantFiled: April 26, 2010Date of Patent: October 30, 2012Assignee: Medtronic Cryocath LPInventors: Marwan Abboud, Dan Wittenberger