Abstract: An infusion set for use with a fluid infusion device is provided. The infusion set can include a mount including a projection having a bore. The projection can be surrounded at least partially by a recess defined through a surface of the mount, and the mount can include at least one rib that spans the recess. The infusion set can include a fluid outlet coupled to at least a portion of the bore of the projection and a coupling device to couple the infusion set to a user. The coupling device can be coupled to the surface and the at least one rib of the mount.

Abstract: A biomaterial delivery device includes an elongated handheld powder storage conduit with proximal and distal ends and a bore having a central axis. The proximal end is closed by a movable powder dispensing actuator, and the distal end is closed by an openable sealing nib moveable from its closed to its open position by force upon the actuator. The distal end has a distally-projecting powder discharge chute that spaces the nib away from a surgical site. When the device is held upright over a surgical site with the nib opened, powder passing the nib is deflected at a first oblique direction with respect to the central axis and into or onto the powder discharge chute, and powder striking the chute is deflected at a rotationally distinct second oblique direction orientation with respect to the central axis and into or onto the surgical site.

Abstract: The invention includes systems, apparatuses and methods to evaluate the strength of clotting in addition to or separate from activated clotting time. The strength of clotting may be correlated with the amount of energy employed to move an object within blood. The strength of clotting may be correlated with the amount of time for fibrinolysis to occur. The strength of clotting may be determined by a system in which a ferromagnetic material is moved within blood.

Abstract: An implantable medical device includes a housing formed of a first material and a first electronic component provided within the housing. The implantable medical device also includes a second material provided in contact with at least a portion of the housing. At least one of the housing and the first electronic component has a magnetic permeability in a magnetic field that differs from the magnetic permeability of water. The second material is provided in an amount effective to reduce MRI image distortion caused by the implantable medical device.

Abstract: A surgical cutting blade for cutting bone material when the blade is coupled to a hand-held surgical saw having protrusions extending therefrom that interface with the cutting blade. The cutting blade includes a distal end comprising a plurality of cutting teeth and a shank portion adjacent the distal end. It also includes a proximal end adjacent the shank portion. The proximal end is shaped to attach to the surgical saw and includes an upper substantially planar surface and a lower substantially planar surface and a side edge extending between the upper and lower planar surfaces. The side edge at least in part defines an outer perimeter extending about the proximal end. The outer perimeter includes a plurality of indentations forming openings configured to receive and interface with the protrusions of the surgical saw in a manner that the protrusions cooperatively impart motion to drive the blade.

Abstract: Devices, systems, and techniques for delivering electrical stimulation according to a spatial electrode movement pattern are disclosed. Moving electrical stimulation between electrodes in a repeatable movement pattern may provide a therapeutic sensation to a patient. In one example, a system may include a plurality of electrodes configured to be implanted within a patient, at least one processor, and a therapy module. The at least one processor may be configured to receive a spatial electrode movement pattern that defines a sequence with which electrical stimulation is moved between the plurality of electrodes. The therapy module may be configured to deliver electrical stimulation to the patient based on the spatial electrode movement pattern.

Abstract: A stent-graft delivery system is disclosed having an outer tubular shaft or sheath with a relatively stiff proximal segment and a distal segment formed from a tubular textile component. The proximal segment being formed from a polymeric tubing and having a distal end attached to a proximal end of the tubular textile component. During tracking of the delivery system through the vasculature, a self-expanding stent-graft is constrained by and within the tubular textile component in a compressed delivery configuration. Upon positioning at a treatment site, such as an aneurysm, retraction of the outer tubular shaft proximally slides the tubular textile component over the stent-graft to expose and deploy the stent-graft. The tubular textile component may be made from strands of one or more biocompatible materials that have been formed into a textile by weaving, braiding, knitting, crocheting, felting or a combination thereof.

Abstract: The present disclosure describes an implantable medical device utilizing an event-triggered prognostic indicator. The disclosure describes techniques for prognostics and management of implantable medical systems to facilitate continuity of performance of sensing and therapy delivery functions by providing adequate response time to handle emerging issues prior to adverse clinical impacts. In accordance with the present disclosure, event-triggered prognostic indicators facilitate the identification of potential device conditions.

Abstract: Techniques, devices, and systems may include screening effective therapies using cortical evoked potentials. In one example, a system may be configured to receive a first sensed cortical evoked potential of a patient that occurred in response to an induced sensation at an anatomical region different from a brain region of the patient and receive a second sensed cortical evoked potential that occurred in response to electrical stimulation delivered to one or more nerves associated with the anatomical region. The electrical stimulation may be at least partially defined by a set of therapy parameter values. The system may also compare a first value of a characteristic of the first sensed cortical evoked potential to a second value of the characteristic of the second sensed cortical evoked potential and determine, based on the comparison, efficacy of a therapy configured to treat a condition associated with the anatomical region.

Abstract: A method and device for delivering therapy that includes an electrode to sense cardiac signals and to deliver a therapy, a monitoring module detecting a cardiac event in response to the sensed cardiac signals using first detection criteria, a sensor emitting light and detecting emitted light scattered by a tissue volume adjacent the sensor to generate a corresponding detected light intensity output signal, a control module coupled to the sensor to control light emission of the sensor in response to delivering the therapy, and a controller coupled to the monitoring module, the therapy delivery module and the sensor, the controller configured to determine tissue oxygenation measurements in response to the output signal, determine a tissue oxygenation trend in response to the tissue oxygenation measurements, determine a recovery index in response to the determined tissue oxygenation trend, and control one or both of detecting a cardiac event by the monitoring module and delivery of therapy by the therapy deliver

Abstract: Medical leads included coiled filars that have longitudinally straight ends. The coiled filars may be coiled at a constant pitch until reaching the point where the filars become longitudinally straight. The coiled filars may reside within a central lumen of the lead body, while the longitudinally straight portions may reside in a region where electrical connectors are present and where filar passageways provide a pathway for the filars to exit the central lumen and bond with the electrical connectors. The coiled filars may be created with longitudinally straight ends using a body that includes longitudinally straight holes that receive the filars and maintain the longitudinally straight configuration while the remaining portion of the filars is being coiled.

Abstract: Electrical stimulation therapy may be delivered to a patient to selectively and independently address different conditions of a pelvic floor disorder of the patient. The conditions of a pelvic floor disorder may include, for example, a lower urinary tract dysfunction (e.g., urinary or fecal incontinence) and sexual dysfunction (e.g., an impaired sexual reflex response to a sexual stimulus). In some examples, a system is configured to selectively deliver a first electrical stimulation therapy that is configured to elicit an inhibitory physiological response from the patient related to voiding, a second electrical stimulation therapy that is configured to improve a sexual reflex response of the patient to a sexual stimulus, and a third electrical stimulation therapy that is configured to both elicit the inhibitory physiological response from the patient related to voiding and increase a sexual response of the patient to a sexual stimulus.

Abstract: Various embodiments concern assessing a degenerative cognitive disorder of a patient based on a plurality of episodes of non-motor epileptiform bioelectrical activity. The non-motor epileptiform bioelectrical activity can be detected from one or more bioelectrical brain signals. A worsening cognitive disorder may be indicated by an increase in one or more of intensity, duration, and frequency of occurrence of the episodes of non-motor epileptiform bioelectrical activity. A therapy can be delivered to reduce one or more of intensity, duration, and frequency of occurrence of the episodes of non-motor epileptiform bioelectrical activity. The delivery of the therapy can be controlled based on the plurality of episodes of non-motor epileptiform bioelectrical activity.

Abstract: A method of a forming a hollow, drug-eluting medical device includes utilizing a hollow wire having an outer member and a lumen of the outer member, and filling the lumen with a fluid to form a supported hollow wire. The supported hollow wire is shaped into a stent pattern. Openings are formed through the outer member. The supported hollow wire is processed to remove the fluid from the lumen of the outer member without adversely affecting the outer member, leaving the hollow wire shaped into a stent pattern. The lumen is filled with a biologically or pharmacologically active substance.

Abstract: One or more efficacious electrode combinations for delivering electrical stimulation therapy to a patient may be selected based on the delivery of electrical stimulation to the patient via a predefined set of test electrode combinations in a predetermined order. In some examples, the electrode combinations of the set are arranged in the predetermined order such that adjacent electrode combinations in the order include at least one shared anode electrode or cathode electrode. In addition, the electrode combinations in the predetermined order may define a predetermined sequence of electrode patterns, each electrode pattern defining a relative arrangement between one or more anodes and one or more cathodes of the respective electrode pattern. In some examples, the transition between electrode combinations in the predefined set is achieved by incrementally adjusting at least one of anodic amplitudes assigned to active anode electrodes or cathodic amplitudes assigned to active cathode electrodes.

Abstract: A component of an implantable medical device comprises a body comprising at least one external surface, the body comprising at least one of titanium, titanium-based alloys, and composites thereof, and a corrosion-resistant surface region at the at least one external surface, the corrosion-resistant surface region comprising at least one of titanium nitride, dititanium nitride, and a solid solution of nitrogen dissolved in the body, wherein the corrosion-resistant surface region is formed by thermal nitridation of the body.

Abstract: A battery having an electrode assembly located in a housing that efficiently utilizes the space available in many implantable medical devices is disclosed. The battery housing provides a cover and a shallow case a preferably planar, major bottom portion, an open top to receive the cover opposing the bottom portion, and a plurality of sides being radiused at intersections with each other and with the bottom to allow for the close abutting of other components located within the implantable device while also providing for efficient location of the battery within an arcuate edge of the device. The cover and the shallow case being substantially hermetically sealed by a laser weld technique and an insulator member disposed within the case to provide a barrier to incident laser radiation so that during welding radiation does not impinge upon radiation sensitive component(s) disposed within the case.

Abstract: A suturing device including an elongated body, a distal tip, at least two support arms, and at least two extendable and retractable needles. The distal tip is moveable between an extended position in which the distal tip distally extends from a distal end of the elongated body and a retracted position in which the distal tip is disposed within the elongated body. The support arms are pivotally coupled to the distal tip. When the distal tip is in the extended position, each support arm is in a collapsed position disposed within the elongated body, and when the distal tip is in the retracted position, each support arm is in a deployed position extending radially away from the elongated body. Each needle includes a distal end configured to penetrate through a vessel wall and capture a suture releasably held within a portion of a support arm.

Abstract: Medical device delivery assemblies are disclosed. The assembly may include a catheter-based delivery system. The assembly may include a pacing element to pace a patient's heart before, during, or after a procedure. The pacing element may be a detachable, implanting pacing element. The pacing element may be an implantable pacemaker and the implantable pacemaker may be disposed on a catheter-based delivery system. The assembly may include a prosthetic heart valve with one or more pacing elements on it. The pacing element may include a pacing strip or strips. These strips may be conductive or insulative. These strips may prevent, treat, or correct abnormal electrical communication in a heart.

Abstract: Devices, systems, and techniques for analyzing video information to objectively identify patient behavior are disclosed. A system may analyze obtained video information of patient motion during a period of time to track one or more anatomical regions through a plurality of frames of the video information and calculate one or more movement parameters of the one or more anatomical regions. The system may also compare the one or more movement parameters to respective criteria for each of a plurality of predetermined patient behaviors and identify the patient behaviors that occurred during the period of time. In some examples, a device may control therapy delivery according to the identified patient behaviors and/or sensed parameters previously calibrated based on the identified patient behaviors.