Abstract: The invention discloses a bilaterally driven integrated medical device, comprising: infusion unit; program unit comprising input end and output end, and the input end comprises a plurality of electrically connective regions for receiving signals of analyte data in the body fluid, after the output end is electrically connected to the power unit, the program unit controls whether the infusion unit delivers drugs; an infusion cannula with conductive area(s); and a plurality of electrodes for detecting analyte data in body fluid, the electrode comprising conductive-area electrode(s) and cannula-wall electrode(s), the conductive area of the infusion cannula being at least as a conductive-area electrode, and one or more cannula-wall electrodes being located on/in the wall of the infusion cannula. It takes only one insertion to perform both analyte detection and drug infusion.

Abstract: The invention discloses a micro-analyte detection device, which comprises a bottom case, the bottom board of the bottom case is provided with a mounting hole; a sensor structure, the sensor structure includes a sensor and a sensor base, and the sensor includes a signal output end and a detection end, and a transmitter, the transmitter includes a transmitter housing and an electronic device, the electronic device is provided with an electrical connection area, when the transmitter is installed in the working position, the electrical connection area is electrically connected with the signal output end. This device effectively reduces the overall thickness of the analyte detection device and enhances the user experience.

Abstract: A sensing device includes a base, a probe structure and a transmitter structure. The base is provided with a first fastener part. The probe structure includes a second fastener part, a probe and a connection area. The transmitter structure includes a transmitter housing and a transmitter disposed inside the transmitter housing, the transmitter housing is provided with a connection hole, the shape of which matches the shape of the probe structure, and when the transmitter structure is mounted to the base, the probe structure is located in the connection hole, and the transmitter is electrically connected to the connection area to receive the signal generated by the probe.

Abstract: A patch-type drug infusion device includes an infusion unit. The infusion unit includes a drug storage unit, a piston, a rigid screw, a rotating shaft, a rotatable driving unit, a driving wheel provided with wheel teeth, a power unit and a rebound unit. The driving unit can rotate around the rotating shaft, driving the driving portion of the driving unit to push the wheel teeth to rotate the driving wheel which engages the rigid screw to move forward in a non-rotating way. The device also includes position detectors, a program unit, an infusion needle and an adhesive patch. The program unit is connected to the infusion unit to control drug infusion and convert received electrical or magnetic signals into the piston position information.

Abstract: A drug infusion device includes a drug storage unit, a driving unit, a position detecting area, a power unit and a control unit. The piston is disposed in the drug storage unit, and a driving rod is connected to the piston. The driving unit includes a driving part and a positioning part. The driving unit drives the driving part and the positioning part to move. The positioning part interacts with the position detecting area at different positions to trigger different position signals. The power unit applies a force to move the driving unit. The control unit is connected to the position detecting area to receive the position signals, according to the position signals, the control unit controls the direction of the force applied by the power unit to move the driving unit and form optional infusion modes.

Abstract: The invention discloses a unilateral-driven medical device with infusion and detection integrated, comprising: drug infusion unit; program unit comprising input end and output end, and the input end comprises a plurality of electrically connective regions for receiving signals of analyte data in the body fluid, after the output end is electrically connected to the power unit, the program unit controls whether the drug infusion unit delivers drugs; and an infusion cannula provided with at least two detecting electrodes, the infusion cannula is the drug infusion channel, the electrodes are disposed on the cannula wall. It takes only one insertion to perform both analyte detection and drug infusion.

Abstract: The invention discloses an integrated drug infusion device, comprising: infusion unit configured to deliver drugs; program unit comprising input end and output end, and the input end comprises a plurality of electrically connective regions for receiving signals of analyte data in the body fluid, after the output end is electrically connected to the infusion unit, according to the received signals of analyte data in the body fluid, the program unit controls whether the infusion unit delivers drugs; an infusion cannula with conductive area, the infusion cannula is the drug infusion channel; and a plurality of electrodes for detecting analyte data in body fluid, the electrode comprising conductive-area electrode and cannula-wall electrode, the conductive area of the infusion cannula being at least as a conductive-area electrode, and one or more cannula-wall electrodes being located on/in the wall of the infusion cannula. It takes only one insertion to perform both analyte detection and drug infusion.

Abstract: The invention discloses a closed-loop artificial pancreas device with integrated detection and infusion, comprising: infusion unit configured to deliver drugs; program unit comprising input end and output end, and the input end comprises a plurality of electrically connective regions for receiving signals of analyte data in the body fluid, after the output end is electrically connected to the infusion unit, according to the received signals of analyte data in the body fluid, the program unit controls whether the infusion unit delivers drugs; an infusion cannula with conductive area, the infusion cannula is the drug infusion channel; and a plurality of electrodes for detecting analyte data in body fluid, the electrode comprising conductive-area electrode and cannula-wall electrode, the conductive area of the infusion cannula being at least as a conductive-area electrode, and one or more cannula-wall electrodes being located on/in the wall of the infusion cannula.

Abstract: A unilaterally driven drug infusion device with multiple infusion modes includes a reservoir, a piston, a screw, a driving unit, at least one driving wheel provided with teeth, a linear actuator, a reset unit, and a control unit. The piston is arranged in the reservoir. The driving unit includes a rotating shaft and a driving member, and the driving member includes a driving end. The linear actuator and the reset unit are respectively connected to the driving member. The control unit controls the linear actuator or the reset unit to apply different driving powers on the driving member to make the driving member have a variety of different operating modes.

Abstract: A miniature patch-type control infusion device includes an infusion unit (102). The infusion unit (102) comprises a drug storage unit(s) (100), a metal piece (110), a piston(s) (120), a rigid screw(s) (130), a rotating shaft (160), a driving unit(s) (150), a driving wheel(s) (140) provided with wheel teeth (141), a power unit(s) (180) and a rebound unit(s) (170). The driving unit (150) includes at least two driving portions (151a, 151b). The driving unit (150) can rotate around the rotating shaft (160) in the driving direction and the returning direction. The power unit (180) and the rebound unit (170) cooperate with each other to apply force to the driving unit (150) to rotate the driving unit (150). The infusion device also includes a position detector(s) (190), the metal piece (110) and the position detector(s) (190) interact to generate signals. Using this infusion device, patients will have more infusion rate options, which increase the flexibility of controlling drug infusion.

Abstract: A drug infusion device with multiple infusion modes, includes: a reservoir (110), a piston (120) and a screw (130), the piston (120) is arranged in the reservoir (110); a driving module at least includes a first driving unit and a second driving unit that cooperate with each other, the second driving unit drives the screw (130) forward; a power module connected to the first driving unit; and a control module (101), connected to the power module, controls the power module to apply different driving powers to the first driving unit, making the first driving unit have a variety of different operating modes, thereby making the infusion device have various different infusion increments or infusion rates. The user or the system can flexibly select the infusion mode, which enhances the user experience.

Abstract: A bilaterally driven drug infusion device with multiple infusion modes comprises: a drug storage unit (150); a piston (160) and a driving wheel (130,630) respectively connected with a screw (170), the driving wheel (130,630), provided with wheel teeth (131,631), drives the screw (170) movement by rotation, the piston (160) is arranged in the drug storage unit (150), the screw (170) advances the piston (160) to move; a driving unit (100,200,300,400,500,600) cooperating with the driving wheel (130,630); and a power unit (180,680), connected to the driving unit (100,200,300,400,500,600), outputs forces in two different directions (A?,B?) on the driving unit (100,200,300,400,500,600) to lead driving unit (100,200,300,400,500,600) to perform multiple-mode operation, making the infusion device have multiple infusion increments or infusion rates.

Abstract: A delivery system of a portable delivery device, using a chamber with three connections structure (10) arranged on the upper housing (1) as a buffer channel for the flow passage of the drug fluid from the external syringe into the reservoir (6) and from the reservoir (6) into the infusion needle; and the structures on the upper, the lower housings (1), (4) and the needle seat (2) accommodating the infusion needle mate with each other sophisticatedly ensuring the compactness of the delivery device and enabling the patient to control the position of the infusion needle safely and conveniently at the same time; in additional, the needle seat cover (7, 8) which covers the needle seat (2) enhances the safety of using the infusion needle. The delivery system of a portable delivery device has advantages of small size, sophisticated structure, simple operation, safety guarantee.

Abstract: The present invention provides a closed loop control method to control an artificial pancreas and the artificial pancreas using this method, comprising constructing an autoregressive model by initiatively introducing the insulin absorption lag factor, calculating an amount of insulin to be delivered at the current time using the autoregressive model and a PID controller respectively, and tuning the parameters of the autoregressive model and the PID controller respectively using the average of the calculation results in order to provide a more accurate prediction of glucose trends and a more desirable amount of insulin delivery.

Abstract: A delivery safety ensuring method for a wearable delivery system, comprising two major steps to double-ensure that an instruction sent from a smart device trying to control the wearable delivery device reflects the true intention of the user. The first step is to restrict a delivery amount instructed by smart device within a pre-determined range using an alternative physical key, and the second step is to require authentication using an independent authentication tool through proximity communication. Both steps of the safety ensuring method require no open network access, solving the problem of the smart device being vulnerable to program failure and external viruses so as to enhance delivery safety, especially against malicious external attacks from open network. A wearable delivery system using this method is further provided.

Abstract: A one step all-in-one apparatus for body fluid sampling and sensing, comprising: a housing(1), a plurality of integrated sampling and sensing assemblies, a cartridge(12), sealing films(101,102), an upper cover(13), a sampling port(6), a linear actuating mechanism and a control circuit, with every integrated sampling and sensing assembly comprising a micro fluid-sampling needle(2), a needle hub(3) and a test strip(4); the micro fluid-sampling needles(2) penetrate the skin to sample the body fluid and deliver the body fluid to the test strips(4) directly, and changes occurred on the test strips(4) are read by the sensor(5), wherein sampling and sensing are completed in one step.

Abstract: A unilateral driving mechanism for a portable infusion system is provided. The unilateral driving mechanism comprises an actuator (1), a swinging part (2), gears (4), blockers (5), a compression spring (6), a rod (7), a reservoir (8), a plunger (9) and a control circuit. One end of the rod (7) is connected with the gears (4), the other end of the rod (7) is connected with the plunger (9), and one lower limb of the swinging part (2) is connected with the spring (6). The unilateral driving mechanism for a portable infusion system has advantages of compact structure, small volume, low power consumption, low cost, high precision and convenience in use.

Abstract: The invention relates to a pulp paper for flexible film zinc-manganese battery, which comprises a base paper with only one layer and slurry coated on both sides which comprises modified starch, polyelectrolyte, water retaining agent, organic/inorganic composite corrosion inhibitor, and electrolytes wherein the polyelectrolyte is one or more of polyglutamic acid, sodium polyglutamate, potassium polyglutamate, polyaspartic acid, sodium polyaspartate and sodium polyaspartate, and the water retaining agent is a sodium salt or a potassium salt of hyaluronic acid. The pulp paper in the invention has the advantages of thin layer, simple composition, fast absorption speed, large liquid absorption capacity, good liquid-retaining ability, good ionic conductivity and low wet resistance which boosts good application value in the field of flexible battery technology.

Abstract: A multi-mode power supply system for a portable infusion device is provided, comprising a Battery I and an Battery II, the Battery I constantly charges the Battery II constituting a charging circuit, which adopts one of multiple charging modes including a basal-rate slow charging mode, a bolus-dose fast charging mode and a background charging mode depending on different drug infusion conditions; the Battery I powers the control unit independently, and the Battery II powers the driving unit independently; a unidirectional conduction circuit, a monitoring circuit and a detecting circuit are further comprised to ensure the normal operation of the power supply system under various circumstances.