Patents Assigned to Mei Pharma, Inc.
  • Isoflavonoid compounds and methods for the treatment of cancer
    Patent number: 9663484
    Abstract: Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in cancer cells by administering such compositions.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: May 30, 2017
    Assignee: MEI PHARMA, INC.
    Inventors: George Jeoffreys, Alison Johnson, Andrew Heaton, Ofir Moreno
  • Benzimidazole derivatives: preparation and pharmaceutical applications
    Patent number: 9402829
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: August 2, 2016
    Assignee: MEI PHARMA, INC.
    Inventors: DiZhong Chen, Hong Yan Song, Eric T. Sun, Niefang Yu, Yong Zou
  • Substituted chroman derivatives, medicaments and use in therapy
    Patent number: 9381186
    Abstract: Novel substituted chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: July 5, 2016
    Assignee: MEI PHARMA, INC.
    Inventors: Andrew Heaton, Alan James Husband
  • Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications
    Patent number: 9266882
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: February 23, 2016
    Assignee: MEI PHARMA, INC.
    Inventors: Ken Chi Lik Lee, Eric T. Sun, Haishan Wang
  • Chroman derivatives, medicaments and use in therapy
    Patent number: 9198895
    Abstract: Novel chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: December 1, 2015
    Assignee: MEI Pharma, Inc.
    Inventors: Andrew Heaton, Alan Husband
  • Substituted chroman derivatives, medicaments and use in therapy
    Patent number: 9138478
    Abstract: Novel substituted chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: September 22, 2015
    Assignee: MEI Pharma, Inc.
    Inventors: Andrew Heaton, Alan James Husband
  • (Alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
    Patent number: 9056852
    Abstract: Provided herein are (alpha-substituted aralkylamino or heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula I, and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: June 16, 2015
    Assignee: Mei Pharma, Inc.
    Inventors: S. David Brown, David J. Matthews
  • Benzimidazole derivatives: preparation and pharmaceutical applications
    Patent number: 9024029
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: May 5, 2015
    Assignee: MEI Pharma, Inc.
    Inventors: DiZhong Chen, Hong Yan Song, Eric T. Sun, Niefang Yu, Yong Zou
  • Chroman derivatives, medicaments and use in therapy
    Patent number: 8957109
    Abstract: Chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: February 17, 2015
    Assignee: MEI Pharma, Inc.
    Inventors: Andrew Heaton, Alan Husband
  • Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications
    Patent number: 8901149
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).
    Type: Grant
    Filed: January 3, 2014
    Date of Patent: December 2, 2014
    Assignee: MEI Pharma, Inc.
    Inventors: Ken Chi Lik Lee, Eric T. Sun, Haishan Wang
  • SUBSTITUTED CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY
    Publication number: 20140170243
    Abstract: Novel substituted chroman derivatives and intermediate compounds, compositions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotherapeutic selective agents are described.
    Type: Application
    Filed: February 21, 2014
    Publication date: June 19, 2014
    Applicant: MEI Pharma, Inc.
    Inventors: Andrew Heaton, Alan James Husband
  • CHROMAN DERIVATIVES, MEDICAMENTS AND USE IN THERAPY
    Publication number: 20140161908
    Abstract: Novel chroman derivatives and intermediate compounds, compostions containing same, methods for their preparation and uses thereof as therapeutic agents particularly as anti-cancer and chemotheraputic selective agents are described.
    Type: Application
    Filed: May 10, 2013
    Publication date: June 12, 2014
    Applicant: MEI Pharma, Inc.
    Inventors: Andrew HEATON, Alan HUSBAND
  • IMIDAZO[1,2-a]PYRIDINE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS
    Publication number: 20140121203
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).
    Type: Application
    Filed: January 3, 2014
    Publication date: May 1, 2014
    Applicant: MEI Pharma, Inc.
    Inventors: Ken Chi Lik Lee, Eric T. Sun, Haishan Wang
  • (FUSED RING ARYLAMINO AND HETEROCYCLYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES
    Publication number: 20140088103
    Abstract: Provided herein are (fused ring arylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula (I), and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases.
    Type: Application
    Filed: March 27, 2012
    Publication date: March 27, 2014
    Applicant: MEI PHARMA, INC.
    Inventors: S. David Brown, David J. Matthews
  • (ALPHA-SUBSTITUTED CYCLOALKYLAMINO AND HETEROCYCLYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES
    Publication number: 20140088102
    Abstract: Provided herein are (alpha-substituted cycloalkylamino or heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula I, and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases.
    Type: Application
    Filed: March 27, 2012
    Publication date: March 27, 2014
    Applicant: MEI PHARMA, INC.
    Inventors: S. David Brown, David J. Matthews
  • BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS
    Publication number: 20140005194
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
    Type: Application
    Filed: September 3, 2013
    Publication date: January 2, 2014
    Applicant: MEI Pharma, Inc.
    Inventors: DiZhong CHEN, Hong Yan SONG, Eric T. SUN, Niefang YU, Yong ZOU
  • Benzimidazole derivatives: preparation and pharmaceutical applications
    Patent number: 8551988
    Abstract: The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: October 8, 2013
    Assignee: Mei Pharma, Inc.
    Inventors: DiZhong Chen, Hong Yan Song, Eric T. Sun, Niefang Yu, Yong Zou