Abstract: Provided is a method of detecting presence or absence of a functional gastrointestinal disorder by measuring bacteria occupancy within a human stomach.

Abstract: An object of the present invention is to provide a simple method of detecting a protein in a liquid, which requires less labor or cost as compared with a conventional method. In the present invention, it has been found that coloring a protein by a color reaction specific to the protein, performing filtration using a filter which easily adsorbs a protein to concentrate the protein on the filter, and checking coloration allows for simply and easily detecting and measuring a protein. In addition, it has been found that filtering a protein using a filter, concentrating the protein on the filter, then coloring the protein by a color reaction specific to the protein, and checking the protein allows simply and easily detecting and measuring a protein.

Abstract: This method for producing fermented milk comprises: a starter inoculation step for inoculating a raw material milk with a starter to obtain a fermented milk base material; a fermentation step for fermenting the fermented milk base material to obtain a fermented milk; and a lactic acid bacteria addition step for adding lactic acid bacteria to the fermented milk.

Abstract: A fermented milk for improving autonomic nervous function containing at least one lactic acid bacterial species of the genus Lactobacillus and its metabolite. The lactic acid bacterial species of the genus Lactobacillus is selected from the group consisting of Lactobacillus delbrueckii, Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus gasseri, Lactobacillus rhamnosus and Lactobacillus acidophilus. The lactic acid bacterial strain of the genus Lactobacillus is preferably Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1(FERM BP-10741).

Abstract: A solid milk may include 0.5 wt % to 4 wt % of free fat, wherein a total fat content, including the free fat, is 5 wt % or higher. The solid milk may have a porosity of 30% to 50% and a solubility of 5 seconds to 180 seconds, where the solubility is defined as a time required to dissolve the solid milk completely when the solid milk is placed in 100 mL of water at 50° C. and shaken at a rate of 1.5 cycles/sec and an amplitude of 30 cm. The solid milk may have a hardness of 30 N to 300 N, where the hardness is defined as a force causing fracture when a load is applied in a direction in which a surface area of a fracture surface of a sample becomes minimal.

Abstract: The present invention provides a method for producing a fermented food, comprising: a fermentation step of fermenting a raw material milk-containing milk preparation solution added with Lactobacillus delbrueckii and Streptococcus thermophilus carrying a prtS gene.

Abstract: An object of the present invention is to provide a fermented milk and polysaccharide capable of inhibiting cancerous cachexia. A fermented milk with cancerous cachexia inhibitory effect according to one aspect of the present invention contains Lactobacillus delbrueckii subsp. bulgaricus as an active ingredient. Also, polysaccharide with cancerous cachexia inhibitory effect according to another aspect of the present invention are produced from the Lactobacillus delbrueckii subsp. bulgaricus. It is preferable that the Lactobacillus delbrueckii subsp. bulgaricus is Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 (accession number: FERM BP-10741).

Abstract: A cacao raw material-containing frozen dessert has a moisture content of 50 mass % or more, and contains 8 mass % or more of a cocoa butter component or 15 mass % or more of cocoa liquor and 0.1 to 4.5 mass % of a water-soluble dietary fiber and/or a dextrin having a weight average molecular weight of 450 or more.

Abstract: The present invention is directed to development of a device which makes it possible to precisely and easily measure, evaluate, and quantify dynamic properties of an alimentary bolus by simulating swallowing of a wide variety of types of food products, and also directed to a method to estimate mouthfeel from the dynamic properties by use of the device.

Abstract: A method for selecting a cancer patient for whom a ketogenic diet therapy would be effective and a method for predicting efficacy of a ketogenic diet therapy in a cancer patient are provided. A method is characterized by obtaining a result of analysis of at least one pre-intake candidate substance selected from the group consisting of acylcarnitine(12:0), acylcarnitine(12:1)-2, acylcarnitine(12:1)-3, acylcarnitine(14:1)-1, acylcarnitine(14:2)-1, acylcarnitine(14:2)-2, acylcarnitine(14:3)-2, acylcarnitine(16:1), acylcarnitine(16:2), anandamide, heptadecenoic acid, hypotaurine, linoleylethanolamide, palmitoleic acid, palmitoylcarnitine, phytosphingosine, quinic acid, uric acid, alanine, citrulline, tryptophan and lysine in a serum derived from a cancer patient prior to intake of a ketogenic diet, and using the result of analysis as an indicator.

Abstract: An object of the present invention is to provide novel composition and agent for promoting the production of a brain-derived neurotrophic factor (BDNF) and a novel method for promoting the production of BDNF. The present invention provides a composition for promoting the production of BDNF and an agent for promoting the production of BDNF, each comprising cacao polyphenols. The present invention also provides a method for promoting the production of BDNF, comprising feeding cacao polyphenols in a daily intake which is effective in promoting the production of BDNF for at least 2 weeks.

Abstract: The invention provides new compositions or combinations thereof for the treatment of cancer. More specifically, the invention provides compositions or combinations thereof for cancer treatment including a high-fat diet. Specifically, the high-fat diet is characterized by having approximately 120 g/day or more, or approximately 70% or more of the total daily energy, from fat, based on a real body weight of 50 kg. The diet is preferably a carbohydrate-restricted high-fat diet, and more preferably provided by a ketone formula and/or MCT oil. The dietary therapy by a high-fat diet of the present invention is provided along with surgical treatment, chemotherapy or radiation therapy, or combinations thereof.

Abstract: The object of invention is to provide solid milk with favorable solubility and enough strength and the method of manufacturing the solid milk. The solid milk of the invention has X-ray diffraction pattern of its surface area that has a main peak of 2?=10-15° at 2?=10-11° or at 2?=12-13°. A method for the manufacture of solid milk comprises compressing powdered milk to obtain compressed powdered milk: humidifying the compressed powdered milk to obtain humidified compressed powdered milk; and drying the humidified compressed powdered milk to obtain the solid milk. A part of amorphous lactose at the surface of the solid milk 12 is crystallized at the steps of humidifying step and drying.

Abstract: The present invention relates to a method for producing a cheese-flavored substance, including adding a bacterial cell disrupted product obtained by disrupting lactic acid bacteria and an enzyme to a milk raw material to cause a reaction. The present invention can provide a method for producing a cheese-flavored substance which can safely and efficiently produce a cheese-flavored substance having a more natural cheese flavor at low-cost with simple operation.

Abstract: An object of the present invention is to provide a diet therapy for suppressing tumor growth of refractory cancer, for treating refractory cancer, or for enhancing the effect of another cancer treatment. The present invention provides a saccharide restricted high fat composition for use in suppressing tumor growth of refractory cancer, treating refractory cancer and/or enhancing the effect of another cancer treatment. The composition of the present invention can comprise about 55% by mass or more of fat based on the total solid content contained in the composition. The composition of the present invention can also comprise about 0% by mass to about 15% by mass of saccharide based on the total solid content contained in the composition. The composition of the present invention can also comprise a medium chain fatty acid oil as fat.

Abstract: It is an object of the present invention to provide a method and the like capable of producing a large amount of fructooligosaccharide-containing oil-based confectionery having low hygroscopicity. In the method for producing fructooligosaccharide-containing oil and fat according to the present invention, fructooligosaccharide is pulverized with at least the oil and fat and an emulsifier in a closed system pulverizer to obtain fructooligosaccharide-containing oil and fat. Then, a fructooligosaccharide-containing oil-based confectionery can be produced from the fructooligosaccharide-containing oil-based confectionery base obtained by mixing the fructooligosaccharide-containing oil and fat with the oil-based confectionery base or the raw material thereof. This fructooligosaccharide-containing oil-based confectionery has extremely low hygroscopicity, and if stored in a good environment, the moisture content can be kept extremely low at the point of 210 days from the time of production.

Abstract: The purpose of the present invention is to provide a ketogenic diet monitoring device for managing the effective state of a ketogenic diet for an animal individually. The ketogenic diet monitoring device of the present invention has a configuration in which the amount of metabolite in gases carried from the inside to the outside of the body of an animal for which the effective state of a ketogenic diet is being managed is measured once and/or a plurality of times over time and monitored.

Abstract: The object of the present invention is to provide a method for manufacturing solid milk having suitable hardness for practical use by manufacturing powdered milk having good compaction moldability. In the manufacturing method of solid milk of the present invention, powdered milk for manufacturing solid milk is produced (S100), and then solid milk is produced by produced powdered milk. This manufacturing process (S100) comprises a gas dispersal process (S112) and a spray drying process (S114). In the gas dispersal process (S112), a prescribed gas is dispersed into liquid milk which is an ingredient of the powdered milk. In the spray drying process (S114), the liquid milk having a dispersed prescribed gas is sprayed, and the sprayed liquid milk is dried. By performing these processes, powdered milk is obtained. Solid milk is manufactured by solidifying the powdered milk.

Abstract: Provided is fermented milk for promoting elevation of amino acid concentration in the blood, by which elevation of amino acid concentration in the blood of a subject can be promoted. By making a subject ingest the fermented milk comprising a milk protein concentration of 1.9% by mass or more, elevation of amino acid concentration in the blood of the subject can be promoted.

Abstract: The present invention provides a novel anticariogenic agent without side effects so that anticariogenic effect can also be obtained in humans who are highly sensitive to oligosaccharides and sugar alcohols. Also, an agent for preventing periodontal disease or for treating periodontal disease which has an effect of preventing or treating periodontal disease and which does not have side effects is provided. The invention relates to an anticariogenic agent and an anticariogenic composition comprising a bifidobacterium, an agent and a composition for preventing periodontal disease comprising a bifidobacterium and an agent and a composition for treating periodontal disease comprising a bifidobacterium.