Patents Assigned to Mektar Therapeutics
  • Pulmonary delivery of active fragments of parathyroid hormone
    Patent number: 7456150
    Abstract: Systemic delivery of parathyroid hormone to a mammalian host is accomplished by inhalation through the mouth of a dispersion of an N-terminal fragment of PTH. It has been found that such respiratory delivery of the PTH fragment provides a pulsatile concentration profile of the PTH in the host's serum. PTH fragment compositions include dry powder formulations having the PTH present in a dry bulking powder, liquid solutions or suspensions suitable for nebulization, and aerosol propellants suitable for use in a metered dose inhaler.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: November 25, 2008
    Assignee: Mektar Therapeutics
    Inventor: John S. Patton