Patents Assigned to MELINTA SUBSIDIARY CORP.
  • Tetracycline compositions
    Patent number: 11944634
    Abstract: The present invention relates to compositions, pharmaceutical compositions, and methods for preparing the same, comprising a tetracycline with improved stability and solubility. Some embodiments include a tetracycline with an excess of a divalent or trivalent cation.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: April 2, 2024
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: David C. Griffith, Serge Boyer, Scott Hecker, Michael N. Dudley
  • Therapeutic uses of pharmaceutical compositions comprising cyclic boronic acid ester derivatives
    Patent number: 11684629
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: June 27, 2023
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: Gavin Hirst, Raja Reddy, Scott J. Hecker, Maxim Totrov, David C. Griffith, Olga Lomovskaya, Michael N. Dudley, Serge Henri Boyer
  • Methods of treating bacterial infections
    Patent number: 11376237
    Abstract: Methods of treating bacterial infection in immunocompromised subjects and subjects with one or more underlying malignancies include administering a combination of meropenem and vaborbactam to the subject. Suitable subjects to be treated can include a subject with a history of ongoing leukemia or lymphoma, a subject that has had an organ transplant, stem cell transplant, bone marrow transplant, or splenectomy, a subject receiving immunosuppressive medications, a subject receiving bone marrow ablative chemotherapy, a subject with neutropenia and subject suffering from or having suffered from a malignancy.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: July 5, 2022
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: Elizabeth Alexander, Jeffrey S. Loutit, Michael N. Dudley
  • Apparatus and continuous flow process for production of boronic acid derivative
    Patent number: 11352373
    Abstract: A process for a continuous production of a boronic acid derivative and an apparatus of performing the process are disclosed.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: June 7, 2022
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: Andreas Pelz, Christian Schuster, Stefan Steinhofer, Clemens Stueckler, Maria Vasiloiu, Christopher Zinganell
  • Apparatus and continuous flow process for production of boronic acid derivative
    Patent number: 11312732
    Abstract: A process for a continuous production of a boronic acid derivative and an apparatus of performing the process are disclosed.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: April 26, 2022
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: Andreas Pelz, Christian Schuster, Stefan Steinhofer, Clemens Stueckler, Maria Vasiloiu, Christopher Zinganell
  • Therapeutic uses of pharmaceutical compositions comprising cyclic boronic acid ester derivatives
    Patent number: 11090319
    Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic boronic acid ester derivatives and their use as therapeutic agents.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: August 17, 2021
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: Gavin Hirst, Raja Reddy, Scott J. Hecker, Maxim Totrov, David C. Griffith, Olga Lomovskaya, Michael N. Dudley, Serge Henri Boyer
  • Cyclic boronic acid ester derivatives and therapeutic uses thereof
    Patent number: 11007206
    Abstract: Method of treating or ameliorating a bacterial infection comprising administering a composition comprising a cyclic boronic acid ester compound in combination with a carbapenem antibacterial agent such as Biapenem, and the pharmacokinetics studies thereof are provided.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: May 18, 2021
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventors: David C. Griffith, Michael N. Dudley, Olga Lomovskaya
  • Pharmaceutical compositions
    Patent number: 10300046
    Abstract: The present invention relates to pharmaceutical compositions useful for administration for treating, preventing, or reducing the risk of microbial infections.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: May 28, 2019
    Assignee: MELINTA SUBSIDIARY CORP.
    Inventor: Danping Li