Patents Assigned to MeMed Diagnostics, Ltd.
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Publication number: 20240103001Abstract: A method of classifying an infectious disease in a subject are disclosed. The method comprises: (a) measuring the amount of at least one protein set forth in Table 4 and at least one protein set forth in Table 6 in a sample derived from the subject; and (b) ruling in or ruling out a viral disease based on the amount of the at least one protein set forth in Table 4 and determining the severity of the viral disease based on the amount of the at least one protein set forth in Table 6.Type: ApplicationFiled: January 18, 2022Publication date: March 28, 2024Applicant: MeMed Diagnostics Ltd.Inventors: Michal ROSENBERG, Oded SHAHAM, Einav SIMON, Roy NAVON, Alon ANGEL, Niv Steven MASTBOIM, Eran EDEN, Kfir OVED
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Patent number: 11921119Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is above a predetermined amount, the subject is treated as a low-risk patient.Type: GrantFiled: October 22, 2020Date of Patent: March 5, 2024Assignee: MeMed Diagnostics Ltd.Inventors: Niv Steven Mastboim, Tanya Michelle Gottlieb, Kfir Oved, Eran Eden
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Patent number: 11883825Abstract: In a cartridge device for analyzing a body liquid, a first member of the cartridge has two or more wells for performing assays, and a second member of the cartridge has a compartment for holding one or more disposable pipette tips.Type: GrantFiled: September 2, 2018Date of Patent: January 30, 2024Assignee: MeMed Diagnostics Ltd.Inventors: Noga Salomon, Kfir Oved, Yana Khalfin, Omer Nahum Katzenelson, Amir Gelman, Moran Brouk Rudich, Roy Navon, Assaf Cohen-Dotan, Eran Eden, Salit Tzaban, Arnon Zangvil, Ofer Halbreich, Matthew Fenwick, Adrian Charles Ian Scott-Murphy, Matthew Hou-Pou Yeung, James William Luther, Barbara Tornaghi, Andrea Besana, Thomas Sanelli Crugnale
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Publication number: 20240029818Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.Type: ApplicationFiled: August 7, 2023Publication date: January 25, 2024Applicant: MeMed Diagnostics Ltd.Inventors: Eran EDEN, Kfir OVED, Roy NAVON, Assaf COHEN-DOTAN, Olga BOICO
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Publication number: 20240026449Abstract: Methods of determining infection type are disclosed based on the amount of CD177 RNA and the amount of IFI44L RNA in a sample obtained from the subject. Additional RNA markers for determining infection type are also disclosed. Kits capable of determining infection type are also disclosed.Type: ApplicationFiled: April 8, 2021Publication date: January 25, 2024Applicant: MeMed Diagnostics Ltd.Inventors: Oded SHAHAM, Niv Steven MASTBOIM, Oren ZARCHIN, Roy NAVON, Eran EDEN, Kfir OVED
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Patent number: 11776658Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.Type: GrantFiled: July 28, 2022Date of Patent: October 3, 2023Assignee: MeMed Diagnostics Ltd.Inventors: Eran Eden, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Olga Boico
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Publication number: 20230204568Abstract: A method of measuring the amount of TNF-related apoptosis-inducing ligand (TRAIL) polypeptide in a fluid sample of a subject in need thereof is disclosed. The method uses a lateral flow immunoassay (LFT) device.Type: ApplicationFiled: February 20, 2023Publication date: June 29, 2023Applicant: MeMed Diagnostics Ltd.Inventors: Kfir OVED, Eran EDEN, BOICO Olga, Gali KRONENFELD, Roy NAVON, Assaf COHEN-DOTAN
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Publication number: 20230184760Abstract: A method of determining an infection type in a subject is disclosed. The method comprises measuring the concentration of a first determinant selected from the group consisting of the determinants which are set forth in Table 1 and a second determinant selected from the group of the determinants which are set forth in Table 2 in a subject derived sample, wherein the concentration is indicative of the infection type.Type: ApplicationFiled: December 8, 2022Publication date: June 15, 2023Applicant: MeMed Diagnostics Ltd.Inventors: Kfir OVED, Eran EDEN, Gali KRONENFELD, Olga BOICO, Roy NAVON, Assaf COHEN-DOTAN
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Publication number: 20230094142Abstract: A method of classifying the severity of a coronaviral infection of a subject is disclosed. The method comprises measuring the TRAIL and/or IP10 protein level in a body liquid sample of the subject, wherein the level is indicative of the severity of the coronaviral infection. Managing treatments for coronaviral infections are also disclosed as well as measuring contagiousness of infections.Type: ApplicationFiled: January 29, 2021Publication date: March 30, 2023Applicant: MeMed Diagnostics Ltd.Inventors: Niv Steven MASTBOIM, Oded SHAHAM, Roy NAVON, Tahel ILAN BER, Shaul LEV, Eran BARASH, Tanya Michelle GOTTLIEB, Meital PAZ, Olga BOICO, Kfir OVED, Eran EDEN
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Publication number: 20230045305Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.Type: ApplicationFiled: September 29, 2022Publication date: February 9, 2023Applicant: MeMed Diagnostics Ltd.Inventors: Kfir OVED, Eran EDEN, Olga BOICO, Gali KRONENFELD, Roy NAVON, Assaf COHEN-DOTAN, Einav SIMON
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Publication number: 20220399074Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.Type: ApplicationFiled: July 28, 2022Publication date: December 15, 2022Applicant: MeMed Diagnostics Ltd.Inventors: Eran EDEN, Kfir OVED, Roy NAVON, Assaf COHEN-DOTAN, Olga BOICO
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Publication number: 20220387997Abstract: A method of conducting a biological assay, comprises obtaining data corelative to a temperature of a reagent, mixing the reagent with a sample to provide a mixture, receiving from the mixture a signal indicative of an amount of an analyte in the sample, and correcting the amount based on the obtained data and on a type of the reagent.Type: ApplicationFiled: June 6, 2022Publication date: December 8, 2022Applicant: MeMed Diagnostics Ltd.Inventors: Omer Nahum KATZENELSON, Meytal SHRAGA, James Douglas D'arcy MCCULLY, Timothy Francis LEE, Oren ZARCHIN, Roy NAVON, Itay GISSIS
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Publication number: 20220326256Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is below a predetermined amount, the subject is treated as a high-risk patient.Type: ApplicationFiled: June 16, 2022Publication date: October 13, 2022Applicant: MeMed Diagnostics Ltd.Inventors: Eran EDEN, Kfir OVED, Assaf COHEN-DOTAN, Roy NAVON, Olga BOICO, Meital PAZ
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Publication number: 20220326238Abstract: A method of measuring risk assessment in a patient with appendicitis is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; and (b) providing a risk assessment based on the TRAIL protein level.Type: ApplicationFiled: June 5, 2022Publication date: October 13, 2022Applicant: MeMed Diagnostics Ltd.Inventors: Kfir OVED, Eran EDEN, Assaf COHEN-DOTAN, Roy NAVON, Niv Steven MASTBOIM, Olga BOICO, Meital PAZ
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Patent number: 11466331Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.Type: GrantFiled: March 2, 2017Date of Patent: October 11, 2022Assignee: MeMed Diagnostics Ltd.Inventors: Kfir Oved, Eran Eden, Olga Boico, Gali Kronenfeld, Roy Navon, Assaf Cohen-Dotan, Einav Simon
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Patent number: 11450406Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.Type: GrantFiled: August 20, 2020Date of Patent: September 20, 2022Assignee: MeMed Diagnostics Ltd.Inventors: Eran Eden, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Olga Boico
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Publication number: 20220236269Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.Type: ApplicationFiled: April 11, 2022Publication date: July 28, 2022Applicant: MeMed Diagnostics Ltd.Inventors: Eran EDEN, Kfir OVED, Assaf COHEN-DOTAN, Roy NAVON, Olga BOICO, Meital PAZ
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Patent number: 11385241Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is below a predetermined amount, the subject is treated as a high-risk patient.Type: GrantFiled: September 27, 2017Date of Patent: July 12, 2022Assignee: MeMed Diagnostics Ltd.Inventors: Eran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Meital Paz
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Patent number: 11353456Abstract: A method of measuring risk assessment in a patient with appendicitis is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; (b) providing a risk assessment based on the TRAIL protein level.Type: GrantFiled: September 27, 2017Date of Patent: June 7, 2022Assignee: MeMed Diagnostics Ltd.Inventors: Kfir Oved, Eran Eden, Assaf Cohen-Dotan, Roy Navon, Niv Steven Mastboim, Olga Boico, Meital Paz
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Patent number: 11340223Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.Type: GrantFiled: July 10, 2017Date of Patent: May 24, 2022Assignee: MeMed Diagnostics Ltd.Inventors: Eran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Meital Paz