Patents Assigned to MeMed Diagnostics, Ltd.
  • Publication number: 20240103001
    Abstract: A method of classifying an infectious disease in a subject are disclosed. The method comprises: (a) measuring the amount of at least one protein set forth in Table 4 and at least one protein set forth in Table 6 in a sample derived from the subject; and (b) ruling in or ruling out a viral disease based on the amount of the at least one protein set forth in Table 4 and determining the severity of the viral disease based on the amount of the at least one protein set forth in Table 6.
    Type: Application
    Filed: January 18, 2022
    Publication date: March 28, 2024
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Michal ROSENBERG, Oded SHAHAM, Einav SIMON, Roy NAVON, Alon ANGEL, Niv Steven MASTBOIM, Eran EDEN, Kfir OVED
  • Patent number: 11921119
    Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is above a predetermined amount, the subject is treated as a low-risk patient.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: March 5, 2024
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Niv Steven Mastboim, Tanya Michelle Gottlieb, Kfir Oved, Eran Eden
  • Patent number: 11883825
    Abstract: In a cartridge device for analyzing a body liquid, a first member of the cartridge has two or more wells for performing assays, and a second member of the cartridge has a compartment for holding one or more disposable pipette tips.
    Type: Grant
    Filed: September 2, 2018
    Date of Patent: January 30, 2024
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Noga Salomon, Kfir Oved, Yana Khalfin, Omer Nahum Katzenelson, Amir Gelman, Moran Brouk Rudich, Roy Navon, Assaf Cohen-Dotan, Eran Eden, Salit Tzaban, Arnon Zangvil, Ofer Halbreich, Matthew Fenwick, Adrian Charles Ian Scott-Murphy, Matthew Hou-Pou Yeung, James William Luther, Barbara Tornaghi, Andrea Besana, Thomas Sanelli Crugnale
  • Publication number: 20240029818
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Application
    Filed: August 7, 2023
    Publication date: January 25, 2024
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Roy NAVON, Assaf COHEN-DOTAN, Olga BOICO
  • Publication number: 20240026449
    Abstract: Methods of determining infection type are disclosed based on the amount of CD177 RNA and the amount of IFI44L RNA in a sample obtained from the subject. Additional RNA markers for determining infection type are also disclosed. Kits capable of determining infection type are also disclosed.
    Type: Application
    Filed: April 8, 2021
    Publication date: January 25, 2024
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Oded SHAHAM, Niv Steven MASTBOIM, Oren ZARCHIN, Roy NAVON, Eran EDEN, Kfir OVED
  • Patent number: 11776658
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: October 3, 2023
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Olga Boico
  • Publication number: 20230204568
    Abstract: A method of measuring the amount of TNF-related apoptosis-inducing ligand (TRAIL) polypeptide in a fluid sample of a subject in need thereof is disclosed. The method uses a lateral flow immunoassay (LFT) device.
    Type: Application
    Filed: February 20, 2023
    Publication date: June 29, 2023
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, BOICO Olga, Gali KRONENFELD, Roy NAVON, Assaf COHEN-DOTAN
  • Publication number: 20230184760
    Abstract: A method of determining an infection type in a subject is disclosed. The method comprises measuring the concentration of a first determinant selected from the group consisting of the determinants which are set forth in Table 1 and a second determinant selected from the group of the determinants which are set forth in Table 2 in a subject derived sample, wherein the concentration is indicative of the infection type.
    Type: Application
    Filed: December 8, 2022
    Publication date: June 15, 2023
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, Gali KRONENFELD, Olga BOICO, Roy NAVON, Assaf COHEN-DOTAN
  • Publication number: 20230094142
    Abstract: A method of classifying the severity of a coronaviral infection of a subject is disclosed. The method comprises measuring the TRAIL and/or IP10 protein level in a body liquid sample of the subject, wherein the level is indicative of the severity of the coronaviral infection. Managing treatments for coronaviral infections are also disclosed as well as measuring contagiousness of infections.
    Type: Application
    Filed: January 29, 2021
    Publication date: March 30, 2023
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Niv Steven MASTBOIM, Oded SHAHAM, Roy NAVON, Tahel ILAN BER, Shaul LEV, Eran BARASH, Tanya Michelle GOTTLIEB, Meital PAZ, Olga BOICO, Kfir OVED, Eran EDEN
  • Publication number: 20230045305
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.
    Type: Application
    Filed: September 29, 2022
    Publication date: February 9, 2023
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, Olga BOICO, Gali KRONENFELD, Roy NAVON, Assaf COHEN-DOTAN, Einav SIMON
  • Publication number: 20220399074
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Application
    Filed: July 28, 2022
    Publication date: December 15, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Roy NAVON, Assaf COHEN-DOTAN, Olga BOICO
  • Publication number: 20220387997
    Abstract: A method of conducting a biological assay, comprises obtaining data corelative to a temperature of a reagent, mixing the reagent with a sample to provide a mixture, receiving from the mixture a signal indicative of an amount of an analyte in the sample, and correcting the amount based on the obtained data and on a type of the reagent.
    Type: Application
    Filed: June 6, 2022
    Publication date: December 8, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Omer Nahum KATZENELSON, Meytal SHRAGA, James Douglas D'arcy MCCULLY, Timothy Francis LEE, Oren ZARCHIN, Roy NAVON, Itay GISSIS
  • Publication number: 20220326256
    Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is below a predetermined amount, the subject is treated as a high-risk patient.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 13, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Assaf COHEN-DOTAN, Roy NAVON, Olga BOICO, Meital PAZ
  • Publication number: 20220326238
    Abstract: A method of measuring risk assessment in a patient with appendicitis is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; and (b) providing a risk assessment based on the TRAIL protein level.
    Type: Application
    Filed: June 5, 2022
    Publication date: October 13, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, Assaf COHEN-DOTAN, Roy NAVON, Niv Steven MASTBOIM, Olga BOICO, Meital PAZ
  • Patent number: 11466331
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: October 11, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Kfir Oved, Eran Eden, Olga Boico, Gali Kronenfeld, Roy Navon, Assaf Cohen-Dotan, Einav Simon
  • Patent number: 11450406
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: September 20, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Olga Boico
  • Publication number: 20220236269
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.
    Type: Application
    Filed: April 11, 2022
    Publication date: July 28, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Assaf COHEN-DOTAN, Roy NAVON, Olga BOICO, Meital PAZ
  • Patent number: 11385241
    Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is below a predetermined amount, the subject is treated as a high-risk patient.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: July 12, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Meital Paz
  • Patent number: 11353456
    Abstract: A method of measuring risk assessment in a patient with appendicitis is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; (b) providing a risk assessment based on the TRAIL protein level.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: June 7, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Kfir Oved, Eran Eden, Assaf Cohen-Dotan, Roy Navon, Niv Steven Mastboim, Olga Boico, Meital Paz
  • Patent number: 11340223
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: May 24, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Meital Paz