Patents Assigned to Mendes S.r.l.
  • Publication number: 20030215429
    Abstract: Disclosed is the use of bacteria endowed with arginine deiminase to induce apoptosis and/or reduce an inflammatory reaction, and pharmaceutical or dietetic compositions containing such bacteria. Also disclosed is a strain of Lactobacillus brevis highly endowed with arginine deiminase.
    Type: Application
    Filed: March 28, 2003
    Publication date: November 20, 2003
    Applicant: Mendes s.r.l.
    Inventor: Claudio De Simone
  • Patent number: 6572854
    Abstract: Disclosed is the use of bacteria endowed with arginine deiminase to induce apoptosis and/or reduce an inflammatory reaction, and pharmaceutical or dietetic compositions containing such bacteria. Also included is a strain of Lactobacillus brevis highly endowed with arginine deiminase.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: June 3, 2003
    Assignee: Mendes S.r.l.
    Inventor: Claudio De Simone
  • Publication number: 20020192276
    Abstract: The use of G class immunoglobulins, particularly immunoglobulins for intravenous use or for intramuscular use to produce a medicine for the local therapeutic treatment of dermatitis, particularly acne, contact dermatitis, atopic dermatitis, eczema and ichthyosis, psoriasis papulosquamous dermatopathies (seborrehic dermatitis, erythrodermia, etc.), as well as fungus, parasite, bacterium and virus infection dermatitis is disclosed. The pharmaceutical composition containing G class immunoglobulins suitable for topical application for the treatment of dermatitis is also disclosed.
    Type: Application
    Filed: May 20, 2002
    Publication date: December 19, 2002
    Applicant: Mendes S.R.L.
    Inventors: Claudio De Simone, Pietro Bruschi
  • Patent number: 6380252
    Abstract: A method is provided for increasing the levels of IGF-1 for the therapeutic treatment or prophylaxis of cytological disorders or diseases related to IGF-1 selected from the group including neuropathies of the optic nerve and of the olfactory nerve, neuralgia of the trigmeninal nerve, Bell's paralysis, amyotrophic lateral sclerosis, osteoporosis, anthropathy, arthritis, cervical spondylosis and hernia of the intervertebral discs clinical syndromes of reduced height, cachexia and acute or chronic hepatic necrosis, Turner's syndrome, sarcopoenia, growth hormone insensitivity syndromes, obesity, asthenia, myasthenia and heart asthenia, immunodeficiences and reperfusion injuries, and for the cicatrization of wounds, the healing of ulcers, the treatment of burns, tissue regeneration, cutaneous, intestinal and hepatic tissue regeneration and the formation of dentine, that includes administering, to a patient in need thereof, at least one selected from the group including L-acetylcarnitine, L-isovalerylcarn
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: April 30, 2002
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Mendes S.R.L.
    Inventor: Claudio De Simone
  • Patent number: 6350782
    Abstract: The present invention provides methods for treating a cellular disorder in a mammal which is induced by elevated levels of ceramide by administering a basic amino acid, acylated basic amino acid, or a pharmaceutically acceptable salt thereof to effectuate lowering the ceramide levels in the mammal.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: February 26, 2002
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Mendes S.r.l.
    Inventor: Sonia Moretti
  • Patent number: 6166077
    Abstract: A method is provided for increasing the levels of IGF-1 for the therapeutic treatment or prophylaxis of cytological disorders or diseases related to IGF-1 selected from the group including neuropathies of the optic nerve and of the olfactory nerve, neuralgia of the trigmeninal nerve, Bell's paralysis, amyotrophic lateral sclerosis, osteoporosis, anthropathy, arthritis, cervical spondylosis and hernia of the intervertebral discs clinical syndromes of reduces height, cachexia and acute or chronic hepatic necrosis, Turner's syndrome, sarcopoenia, growth hormone insensitivity syndromes, obesity, asthenia, myasthenia and heart asthenia, immunodeficiencies and reperfusion injuries, and for the cicatrization of wounds, the healing of ulcers, the treatment of burns, tissue regeneration, cutaneous, intestinal and hepatic tissue regeneration and the formation of dentine, that includes administering, to a patient in need thereof, at least one selected from the group including L-acetylcarnitine, L-isovalerylcarnitine, an
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: December 26, 2000
    Assignees: Sigma-TAU Industrie Farmaceutiche Riunite S.p.A., Mendes S.r.l.
    Inventor: Claudio De Simone
  • Patent number: 6114385
    Abstract: The therapeutic use of basic amino acids, acylated basic amino acids and their pharmacologically acceptable salts is disclosed for the treatment of a cellular disorder in a mammal which is induced by elevated levels of ceramide.
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: September 5, 2000
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Mendes s.r.l.
    Inventor: Sonia Moretti
  • Patent number: 6040346
    Abstract: The present invention provides a novel use of L-carnitine, the derivatives thereof and their pharmacologically acceptable salts in combination with antiretroviral drugs for reducing ceramide levels and enhance the activity of the aforesaid antiretroviral drugs for the therapeutic treatment of HIV-infection and AIDS.
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: March 21, 2000
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Mendes s.r.l.
    Inventor: Sonia Moretti
  • Patent number: 6037372
    Abstract: The use of an alkanoyl-L-carnitine, e.g., acetyl-L-carnitine, or a pharmacologically acceptable salt thereof is disclosed to produce a medicament for the therapeutic treatment or prophylaxis of glutamate-mediated cytological disturbances or diseases.
    Type: Grant
    Filed: September 15, 1998
    Date of Patent: March 14, 2000
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Mendes s.r.l.
    Inventor: Sonia Moretti
  • Patent number: 5719192
    Abstract: A method of use comprising administering terbinafine for the primary and secondary prophylaxis and treatment of Pneumocystis carinii pneumonia, including oral administration of terbinafine at does of 3 to 20 mg/kg/day, to a subject suffering from this type of pneumonia is disclosed.
    Type: Grant
    Filed: September 12, 1995
    Date of Patent: February 17, 1998
    Assignee: Mendes s.r.l.
    Inventors: Claudio De Simone, Carlo Contini, Sonia Tzoutzoglou