Abstract: A mammary implant and method of making are provided herein. The implant includes an outer shell configured to retain fluid therein, an injection element coupled to the outer shell and adapted to receive therethrough an injection device for injecting fluid into the outer shell, and an injection marker zone made of a material having ultrasonically detectable markers incorporated therein. The markers are a plurality of microcavities that are located relative to the injection element so that, when ultrasonically detected, such detection indicates a location of the injection element.

Abstract: The present disclosure describes various embodiments of adjustable implants, particularly permanent breast implants, intended for implantation into a subject, particularly a human subject. In some embodiments, the adjustable implant comprises a shell including a resilient shell membrane, a first reservoir containing a fluid, e.g., a saline, a second reservoir including a resilient second-reservoir membrane, and a pump. The pump may include a first pump actuator, a first pump inlet, and a first pump outlet. The first reservoir and second reservoir may be disposed within the shell and be in fluid communication via the pump. Fluid may be transferred between the two reservoirs to change the profile of the implant.

Abstract: An adjustable implant is disclosed herein. The adjustable implant may comprise a shell including membrane and a base and having a first diameter in a plane parallel to the base. A band may be disposed within the shell. The band may have a first end and a second end connected to a spool. The band may be in a round (e.g., elliptical) configuration having a second diameter in the plane that is less than the first diameter. By wrapping the band onto the spool, the diameter of the band may be decreased and the height of the implant may be increased. By unwrapping the band from the spool, the diameter of the band may be increased and the height of the implant may be decreased.

Abstract: Various embodiments of an adjustable implant are disclosed herein. The adjustable implant comprises a hydraulic mechanism disposed within the shell, which includes a first component and a second component that is moveable with respect to the first component, and a band with a first and second end disposed within the shell in a round (e.g., elliptical) configuration having a second diameter in the plane that is less than the first diameter. In some embodiments, the first end of the band may be connected to the first component and the second end of the band may be connected to the second component. In some embodiments, the mechanism may include a fluid and a pump that has a first actuator comprising a first chamber and a second actuator comprising a second chamber. Depressing the first actuator causes the first component to move in a first direction, which reduces the diameter of the band and increases the height of the implant.

Abstract: An expandable mammary implant including a shell having an anterior face and a posterior face. The anterior has an upper pole portion and a lower pole portion meeting at an apex, and an injection zone for receiving fluid therethrough to inflate the implant. A reinforcement material is coupled to the shell in a reinforcement zone. The reinforcement material is coupled to the shell so as to at least coincide with the upper pole portion and a peripheral rim portion that extends from the posterior face upwardly into said anterior face by a predetermined distance.

Abstract: An expandable mammary implant including a shell having an anterior face and a posterior face. The anterior has an upper pole portion and a lower pole portion meeting at an apex, and an injection zone for receiving fluid therethrough to inflate the implant. A reinforcement material is coupled to the shell in a reinforcement zone. The reinforcement material is coupled to the shell so as to at least coincide with the upper pole portion and a peripheral rim portion that extends from the posterior face upwardly into said anterior face by a predetermined distance.

Abstract: A mammary implant and method of making are provided herein. The implant includes an outer shell configured to retain fluid therein, an injection element coupled to the outer shell and adapted to receive therethrough an injection device for injecting fluid into the outer shell, and an injection marker zone made of a material having ultrasonically detectable markers incorporated therein. The markers are a plurality of microcavities that are located relative to the injection element so that, when ultrasonically detected, such detection indicates a location of the injection element.

Abstract: A mammary implant and method of making are provided herein. The implant includes an outer shell configured to retain fluid therein, an injection element coupled to the outer shell and adapted to receive therethrough an injection device for injecting fluid into the outer shell, and an injection marker zone made of a material having ultrasonically detectable markers incorporated therein. The markers are a plurality of microcavities that are located relative to the injection element so that, when ultrasonically detected, such detection indicates a location of the injection element.

Abstract: An expandable mammary tissue implant including a shell having an anterior face and a posterior face, the anterior face having an upper pole portion and a lower pole portion meeting at an apex, and an injection zone for receiving fluid therethrough to inflate the implant. The implant further includes a vertical tether member having first and second ends and a central region therebetween having an aperture therethrough. The central region is coupled to the anterior face of the implant at a location such that the injection zone is positioned within the aperture in the central region. The first and second ends of the vertical tether member are coupled to the posterior face of the implant.

Abstract: An expandable mammary implant including a shell having an anterior face and a posterior face. The anterior has an upper pole portion and a lower pole portion meeting at an apex, and an injection zone for receiving fluid therethrough to inflate the implant. A reinforcement material is coupled to the shell in a reinforcement zone. The reinforcement material is coupled to the shell so as to at least coincide with the upper pole portion and a peripheral rim portion that extends from the posterior face upwardly into said anterior face by a predetermined distance.

Abstract: An acellular matrix glue and a method of making is disclosed. Specifically, an acellular matrix glue that is useful in preparing a reinforced acellular matrix for medical applications including tissue engineering and hernia repair.

Abstract: A valve assembly for an implant has an inner shell, a self-sealing material disposed within the inner shell, and an insertion pathway extending through the self-sealing material. At least one gap is formed in the self-sealing material that intersects with the insertion pathway to define a proximal pathway section and a distal pathway section. A filling tube is passed through the valve assembly for filling the outer shell of the implant with a fluid. After the implant is filled, the filling tube is removed. As the filling tube is removed, if the self-sealing material within the distal section of the pathway is unable to self-seal before the fluid reaches its proximal end, the fluid is diverted into the gap. The time that elapses before the gap is completely filled by the fluid provides sufficient time for the self-sealing material within the proximal section of the pathway to self-seal.

Abstract: Shells for mammary prostheses and other devices are created by spraying a silicone dispersion onto a mandrel. Several coats of dispersion are applied with an interval for evaporation of solvent from the dispersion between application of coats. The shells created are uniform in thickness and have a desirably defect-free surface.

Abstract: A coating with antimicrobial agents for use with medical devices. In one approach, a related method involves coating high temperature vulcanized silicone material with a room temperature vulcanized dispersion.

Abstract: Methods for applying surface texture to the exterior of bodily implants, as well as implants made by the methods described.

Abstract: A coating with antimicrobial agents for use with medical devices. In one approach, a related method involves coating high temperature vulcanized silicone material with a room temperature vulcanized dispersion.

Abstract: A breast implant includes an implant shell having an outer surface and defining a first fluid reservoir, and a porous membrane overlying the outer surface of the implant shell and defining a second fluid reservoir. The breast implant includes a filling tube having a first conduit in communication with the first reservoir and a second conduit in communication with the second reservoir. The breast implant includes an injection dome coupled with the filling tube and having a first fluid chamber in communication with the first conduit and a second fluid chamber in communication with the second conduit. The injection dome includes an upper end having an injection cover, a lower end including a support base, the first fluid chamber located adjacent the injection cover, the second fluid chamber located adjacent the support base, and a diaphragm dividing the first and second fluid chambers from one another.

Abstract: A flow delivery system including a syringe that includes an outer plastic shell, a leur and a plunger; and a needle and/or a catheter that embodies a hub and a cannula which delivers a solution of a material. Various structures are included to provide locking engagements, torque sensitive connections, sufficient interfacing between components and visual conformation of connectors. The syringe assembly can also include an approach to a filter. Moreover, an approach to sterilization is provided.

Abstract: The present invention relates to a process for the production of cross-linked hyaluronic acid (HA) derivatives, in particular multiple, e.g. double cross-linked hyaluronic acid derivatives. The invention also provides novel cross-linked HA derivatives, products containing them and their uses in medical and pharmaceutical and cosmetic applications.

Abstract: Methods for applying surface texture to the exterior of bodily implants, as well as implants made by the methods described.