Abstract: Systems and methods for selecting a prior comparison study. One system includes an electronic processor configured to, for a medical image study associated with a patient, select a prior comparison image study. The electronic processor is also configured to automatically determine, based on monitored user interaction with the selected prior comparison image study, a usefulness of the selected prior comparison image study. The electronic processor is also configured to automatically update a selection model based on the usefulness of the prior comparison image study to a user.

Abstract: Methods and systems for rending medical images within a web browser application. The web browser application retrieves a worklist and automatically determines an image study from the worklist to be cached. The web browser application retrieves at least one medical image included in the image study. The web browser application creates a web database for storing the at least one medical image within the browser application. When a user selects a medical image for display within the web browser, the web browser application determines whether the medical image is stored in the web database. When the medical image is stored in the web database, the web browser application retrieves the medical image from the web database. When the medical image is not stored in the web database, the web browser application retrieves the medical image from a remote image repository.

Abstract: Systems and computer-implemented methods of performing image registration. One method includes receiving a first image and a second image acquired from a patient at different times and, in each of the first image and the second image, detecting an upper boundary of an imaged object in an image coordinate system and detecting a lower boundary of the imaged object in the image coordinate system. The method further includes, based on the upper boundary and the lower boundary of each of the first image and the second image, cropping and padding at least one of the first image and the second image to create an aligned first image and an aligned second image and executing a registration model on the aligned first image and the aligned second image to compute a deformation field between the aligned first image and the aligned second image.

Abstract: Disease detection from medical images is provided. In various embodiments, a medical image of a patient is read. The medical image is provided to a trained anatomy segmentation network. A feature map is received from the trained anatomy segmentation network. The feature map indicates the location of at least one feature within the medical image. The feature map is provided to a trained classification network. The trained classification network was pre-trained on a plurality of feature map outputs of the segmentation network. A disease detection is received from the trained classification network. The disease detection indicating the presence or absence of a predetermined disease.

Abstract: A conversation management system provides a conversational computing interface that manages verbal exchanges between a computer (e.g., artificial intelligence) and a human operator. In a medical embodiment, conversational input from the computing system is generated based on medical knowledge, uses deep learning algorithms, and/or intelligently tracks the state of a conversation so as to the most relevant data to the user.

Abstract: A conversation management system provides a conversational computing interface that manages verbal exchanges between a computer (e.g., artificial intelligence) and a human operator. In a medical embodiment, conversational input from the computing system is generated based on medical knowledge, uses deep learning algorithms, and/or intelligently tracks the state of a conversation so as to the most relevant data to the user.

Abstract: Methods and systems are provided for detecting focal lesions in multi-phase or multi-sequence medical imaging studies of medical images. One system includes memory for storing medical images and an electronic processor. The electronic processor is configured to: detect native candidate lesions for first phase computer tomography (CT) scans, detect candidate lesions for second phase CT scans, and project the candidate lesions detected for the first phase CT scans and/or the second phase CT scans on a same common domain. Once the candidate lesions are registered together, the electronic processor performs a matching algorithm for each of the native candidate lesions of the first phase CT scans with the registered candidate lesions from the second phase CT scans to determine presence and contours of valid lesions for the medical images, and to discard candidate lesions that are not acceptable.

Abstract: A computer system identifies a medical condition in a patient. A trained machine learning image generator is used to generate a set of training images based on three-dimensional patient imaging data, wherein each training image is labeled with a projection angle of the corresponding two-dimensional projection. Using the set of training images, a machine learning image classifier model is trained to identify patient rotation angles in x-ray images. X-ray images are processed with the machine learning image classifier model to identify patient rotation angles. A machine learning medical condition classifier model is trained to identify a medical condition using the labeled x-ray images. The machine learning medical condition classifier model determines an indication of the medical condition in a patient's x-ray image. Embodiments of the present invention further include a method and program product for identifying a medical condition in a patient in substantially the same manner described above.

Abstract: Methods and systems are directed to training an artificial intelligence engine. One system includes an electronic processor configured obtain a set of reports corresponding to a set of medical images, determine a label for a finding of interest, and identify one or more ambiguous reports in the set of repots. Ambiguous reports do not include a positive label or a negative label for the finding of interest. The electronic processor is also configured to generate an annotation for each of the one or more ambiguous reports in the set of reports, and train the artificial intelligence engine using a training set including the annotation for each of the one or more ambiguous reports and non-ambiguous reports in the set of reports. A result of the training is generation of a classification model for the label for the finding of interest.

Abstract: Methods and systems for detecting a vertebral fracture within an x-ray. One method includes receiving a chest x-ray image and identifying a plurality of vertebrae represented in the chest x-ray image. The method further includes extracting a plurality of image patches from the chest x-ray image, each image patch of the plurality of image patches including a portion of the chest x-ray image representing one of the plurality of vertebrae identified in the chest x-ray image. The method further includes sequencing the plurality of image patches into an ordered sequence of image patches, and assigning, with a deep learning model applied to the ordered sequence of image patches, a classification to each of the plurality of image patches indicating whether the image patch represents a fractured vertebra or an unfractured vertebra.

Abstract: Techniques for dynamic visualization of data are provided. A plurality of therapies is received, where each of the plurality of therapies is associated with a respective plurality of guidelines. A guideline tree is generated based on the plurality of therapies, where each leaf node in the guideline tree represents a respective therapy, and where each edge in the guideline tree represents a respective guideline. A visual depiction of the guideline tree is generated. Further, a first plurality of attributes associated with a first patient is received, and a first modified visual depiction of the guideline tree is generated based on the first plurality of attributes.

Abstract: Computer based methods, systems, and computer readable media for intelligently accessing various types of pharmaceutical information in a content repository and ranking drugs at the variant level, gene level, and pathway level. In some cases, drugs that target the same gene, gene variant, or biological pathway may be ranked based upon in vitro, pre-clinical, clinical, or post-clinical evidence. To determine ranking of a plurality of drugs, information pertaining to drug administration is analyzed for the drugs. For a plurality of drugs, attributes corresponding to the drug are determined, wherein the attributes include a variant or a gene targeted by the drug, and a biological pathway comprising the targeted variant or gene. The plurality of drugs are ranked according to a drug effectiveness score based on one or more of a determined efficacy, potency, or toxicity.

Abstract: Systems and methods for developing a classification model for classifying medical reports, such as radiology reports. One method includes selecting, from a corpus of reports, a training set and a testing set, assigning labels of a modality and an anatomical focus to the reports in both sets, and extracting a sparse representation matrix for each set based on features in the training set. The method also includes learning, with one or more electronic processors, a correlation between the features of the training set and the corresponding labels using a machine learning classifier, thereby building a classification model and testing the classification model on the reports in the testing set for accuracy using the sparse representation matrix of the testing set. The method further includes predicting, with the classification model, labels of an anatomical focus and a modality for remaining reports in the corpus not included in the sets.

Abstract: A plurality of attributes are extracted from a plurality of electronic health records, where each electronic health record is associated with a patient in a plurality of patients. Additionally, a training data set and a scoring data set are generated based on the plurality of attributes, and a patient similarity model is trained based on the training data set. A precision cohort is identified, where the precision cohort includes patients in the plurality of patients from the scoring data set that are similar to a first patient based on an electronic health record of the first patient and the similarity model. At least one result statistic for each of a plurality of treatments given to patients in the precision cohort is determined, and a first treatment of the plurality of treatments is selected for the first patient based at least in part on the determined result statistics.

Abstract: Techniques are provided detecting diluted drugs using machine learning. Measurements and images corresponding to a product are obtained, wherein the product is formulated as a liquid, and wherein the measurements and images capture physical, spectral, optical, and/or chemical properties of the product. The measurements and images are provided to a machine learning model, wherein the machine learning model is trained using data generated from interactive learning modules (e.g., a generative adversarial network). The machine learning model detects whether the product or chemical is a real or counterfeit product. In addition, these techniques may be used by practitioners (e.g., medical personnel dispensing a prescribed dosage of a drug with a specific dilution level) to detect prescription errors at the point of administration.

Abstract: A computer system manages a health condition based on conditions of an environment. Health information of a user is analyzed to determine a health condition affected by environmental conditions. One or more events for the user are obtained based on personal information. The environmental conditions for one or more event locations are determined. One or more preventive items are indicated for the user to attend the one or more events in order for the health condition to tolerate the environmental conditions of the one or more event locations. Embodiments of the present invention further include a method and program product for managing a health condition based on conditions of an environment in substantially the same manner described above.

Abstract: Computer based methods, systems, and computer readable media for providing genomic services are provided. A request is received from a user. The request is applied to one or more from a group of a personalized data repository for the user and supporting knowledge bases, wherein the personalized data repository includes genetic test results, health/clinical information, and insurance coverage, and wherein the knowledge bases include information pertaining to genetic tests and clinical guidelines. Data from the applied request is integrated with results from service modules performing one or more from a group of content search, variation interpretation, and report generation to produce results for the request. The personalized data repository and supporting knowledge bases are updated based on the results of the request. Surveillance services are triggered based on one or more events.

Abstract: Methods and systems are provided for detecting a mental health condition. Structured and unstructured information is analyzed using natural language processing to extract information including clinical data values and medical concepts pertaining to a user. Reference medical information is evaluated using natural language processing to correlate medical data with mental health conditions. A classification for a mental health condition of the user is determined using a machine learning model and based on the extracted information and correlations, wherein the extracted information includes blood analysis for the user. The user is assigned to a segment of users based on the extracted information. A treatment for the mental health condition of the user is indicated based on the classification and the assigned segment of users.

Abstract: Techniques are provided for detecting counterfeit products. Measurements and images corresponding to a product are obtained, wherein at least a portion of the measurements or images are obtained from a mobile/IoT/IoB device. The measurements and images are provided to a trained machine learning model to progressively analyze the measurements and images. Based on the progressive analysis, a determination/prediction is made with an associated confidence score as to whether the product is real or counterfeit.

Abstract: Techniques for identifying missing evidence are provided. A plurality of documents, each comprising digitally encoded natural language text data, is received. The plurality of documents is processed to determine a plurality of pair-wise comparisons between a plurality of therapies, where each of the plurality of pair-wise comparisons indicate a relative efficacy of at least one therapy in the plurality of therapies, as compared to at least one other therapy in the plurality of therapies. A knowledge graph is generated based at least in part on aggregating the plurality of pair-wise comparisons, and the knowledge graph is analyzed to identify one or more knowledge gaps within the knowledge graph. Finally, at least an indication of the identified one or more knowledge gaps is output.