Patents Assigned to Merck Patent Gesellschaft mit beschrankter
  • Publication number: 20130146818
    Abstract: The invention relates to novel anthra[2,3-b:7,6-b?]dithiophene derivatives, methods of their preparation, their use as semiconductors in organic electronic (OE) devices, and to OE devices comprising these derivatives.
    Type: Application
    Filed: July 14, 2011
    Publication date: June 13, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Changsheng Wang, Steven Tierney, William Mitchell, Nicolas Blouin, Mansoor D'Lavari
  • Publication number: 20130148069
    Abstract: The present invention relates to liquid-crystal media and liquid-crystal displays (LC displays) comprising these media with homeotropic (vertical) alignment of the liquid-crystalline medium (LC medium). The LC medium having positive dielectric anisotropy according to the invention comprises particles having a mass of at least 450 Da which have been functionalised by a polar, organic anchor group. It is preferably stabilised by a polymerisable component.
    Type: Application
    Filed: July 21, 2011
    Publication date: June 13, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Graziano Archetti, Markus Czanta
  • Publication number: 20130137100
    Abstract: The present invention relates to a genetically modified bacterium of the species Listeria monocytogenes, wherein the genomic locus of the transcriptional factor PrfA has been deleted, characterised in that it comprises on genomic level an artificial sequence that acts as internal amplification control, the use of this bacterium as well as a method for detecting and determining qualitatively and/or quantitatively the occurrence of wild type Listeria monocytogenes in a sample suspected to be contaminated with said micro-organism and a kit.
    Type: Application
    Filed: April 29, 2011
    Publication date: May 30, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Peter Rossmanith, Karin Fruehwirth, Martin Wagner, Sabine Fuchs
  • Publication number: 20130128165
    Abstract: The present invention discloses a liquid crystal display of the IPS type, which has improved characteristics in terms of stability of liquid crystal element, response time, threshold voltage, and driving voltage due to conferring a pretilt angle to a liquid crystal layer, and method for preparation thereof.
    Type: Application
    Filed: July 8, 2011
    Publication date: May 23, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Seung Hee Lee, Dae Hyun Kim, Dong Won Kwon
  • Publication number: 20130119312
    Abstract: The present invention relates to liquid-crystalline media (LC media) comprising thiophene derivatives and to liquid-crystal displays (LC displays) containing these LC media. The media have high optical anisotropy and preferably have a content of thiophene derivatives of 25% by weight or more.
    Type: Application
    Filed: July 1, 2011
    Publication date: May 16, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Michael Wittek, Brigitte Schuler, Axel Jansen
  • Publication number: 20130119311
    Abstract: The present invention relates to liquid-crystalline media and display devices comprising polymerisable compounds, to the use of the polymerisable compounds for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays having a polymer-stabilised blue phase, and in LC media for LC displays of the PS or PSA (“polymer sustained” or “polymer sustained alignment”) type. The polymerisable compounds comprise a ring system which is functionalised by three or more polymerisable groups, each connected via an optional spacer group.
    Type: Application
    Filed: June 29, 2011
    Publication date: May 16, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Axel Jansen, Thorsten Kodek, Helmut Haensel, Erdal Durmaz, Julia Sprang
  • Publication number: 20130118380
    Abstract: A system of N?3 interference pigments, which is distinguished in that it exhibits a maximum color gamut through specification of the optimum pigment hue angle hu?v?i (i=1 to N) in the CIELUV system.
    Type: Application
    Filed: August 9, 2012
    Publication date: May 16, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Michael ROESLER, Adalbert HUBER
  • Publication number: 20130121014
    Abstract: The invention relates to carbodiimide compounds of the general formula (I) EA2-y Si(CN2)4-xOx:Euy where EA stands for one or more elements selected from Mg, Ca, Sr, Ba or Zn and x stands for a value from the range from 0 to 3.9 and Y stands for a value from the range from 0.01 to 0.4, and a process for the preparation of these phosphors and the use thereof as conversion phosphors or in lamps.
    Type: Application
    Filed: June 24, 2011
    Publication date: May 16, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Holger Winkler, Andreas Benker, Ralf Petry, Tim Vosgroene
  • Publication number: 20130114034
    Abstract: The present invention relates to liquid-crystal displays (LC displays) with polymer-stabilised, homeotropic (vertical) alignment of the liquid-crystalline medium (LC medium) without conventional imide alignment layers. The LC medium according to the invention comprises particles having a mass of at least 450 Da which have been functionalised by a polar, organic anchor group.
    Type: Application
    Filed: June 29, 2011
    Publication date: May 9, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Graziano Archetti, Andreas Taugerbeck, Renate Bender
  • Publication number: 20130115178
    Abstract: The invention relates to the use of alduronic acids and dialdehydes of the aldoses and derivatives thereof as tanning enhancers for dihydroxyacetone or for a mixture of self-tanning substances comprising dihydroxyacetone or as self-tanning substance. The invention furthermore relates to the use thereof for modulation of the hue achieved in the case of tanning with dihydroxyacetone or by the mixture or preparation comprising dihydroxyacetone. The invention furthermore relates to the use thereof as contrast reduction agent in a mixture or preparation comprising at least dihydroxyacetone as self-tanning substance. The use of such compounds enables a significantly improved colouring result of the skin.
    Type: Application
    Filed: June 24, 2011
    Publication date: May 9, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Valerie Bicard-Benhamou, Christophe Carola
  • Patent number: 8435986
    Abstract: Compounds of the formula (I), in which X1, X2, X3, X4, X5, R1, R2, R3, R3?, R4, R6 and R7 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: May 7, 2013
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Frank Stieber, Oliver Schadt, Dieter Dorsch, Andree Blaukat
  • Patent number: 8436186
    Abstract: Compounds of the formula (I), in which R1, R2, R3, R4, R5, R6, R9, R10, R11, Q and W have the meanings indicated in Claim 1, and precursors thereof are inhibitors of sphingosine kinase and can be employed, inter alia, for the treatment of tumors.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: May 7, 2013
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Frank Stieber, Timo Heinrich, Dirk Wienke
  • Patent number: 8435981
    Abstract: Compounds of the formula (I) in which R1, R2, R3, R4 and R5 have the meanings indicated in claim 1 are inhibitors of tyrosine kinases, in particular of met kinase and can be employed inter alia for the treatment of tumors.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: May 7, 2013
    Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat, Frank Stieber
  • Publication number: 20130108565
    Abstract: The invention relates to the use of specific disaccharides and derivatives thereof as self-tanning substance or as tanning enhancer for dihydroxyacetone or for a mixture of self-tanning substances comprising dihydroxyacetone. The invention furthermore relates to the use thereof for the modulation of the hue which is achieved on tanning with dihydroxyacetone or by the mixture or preparation comprising dihydroxyacetone. The invention furthermore relates to the use thereof in a mixture or preparation comprising at least dihydroxyacetone as self-tanning substance as contrast-reduction agent. The use of such compounds facilitates a significantly improved colouring result of the skin.
    Type: Application
    Filed: June 24, 2011
    Publication date: May 2, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Valerie Bicard-Benhamou, René Peter Scheurich
  • Patent number: 8431572
    Abstract: Described are compounds which inhibit, regulate and/or modulate kinase signal transduction, for example of Met kinase. The compounds are of the formulae A1 to A148 and B1 described herein, including 2-oxobenzoxazol-3-ylmethyl]phenyl}carbamate and 2-oxooxazolo[4,5-b]pyridin-3-ylmethyl)phenyl]carbamate compounds, and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. Also described are compositions containing these compounds. Also described are methods for the treatment of diseases in which the inhibition, regulation and/or modulation of kinase signal transduction plays a role by administering these compounds.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: April 30, 2013
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Oliver Schadt, Dieter Dorsch, Frank Stieber, Andree Blaukat
  • Patent number: 8431602
    Abstract: Novel heterocyclic compounds of the formula I in which R1, R2, R2?, R2?, R3, R4, R5, R6, R7 and R8 have the meanings indicated in Claim 1, are activators of glucokinase and can be used for the prevention and/or treatment of Diabetes Typ 1 and 2, obesity, neuropathy and/or nephropathy.
    Type: Grant
    Filed: December 23, 2008
    Date of Patent: April 30, 2013
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Stefan Bender, Lars Thore Burgdorf, Ulrich Emde, Norbert Beier, Johannes Gleitz, Christine Charon
  • Publication number: 20130102493
    Abstract: The invention relates to a method for screening compounds with (pro-)genotoxic activity by providing a cellular system being capable of expressing at least a panel of 11 defined genes, incubating at least a portion of the system with compounds to be screened, and comparing the expression of the genes in the system with the gene expression in a control cellular system, thereby detecting the (pro-)genotoxic activity. Another object of the invention concerns a method for monitoring physiological and/or pathological conditions, which are caused, mediated and/or propagated by the genetic deregulation of proliferation, differentiation and/or damage repair, by administering an effective amount of at least a single (pro-)genotoxic compound to a mammal in need of such treatment and determining an expression of 11 defined genes in a biological sample withdrawn from the mammal.
    Type: Application
    Filed: June 3, 2011
    Publication date: April 25, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Stefan Otto Mueller, Philip Hewitt, Kathleen Boehme
  • Publication number: 20130102108
    Abstract: The invention relates to a preparation process for thin semiconducting inorganic films comprising various metals (Cu/In/Zn/Ga/Sn), selenium and/or sulfur. The process uses molecular precursors comprising metal complexes with oximato ligands. Copper-based chalcopyrites of the I-III-IV2-type are prepared with high purity at low temperatures under ambient conditions. The thin films can be used in photovoltaic panels (solar cells).
    Type: Application
    Filed: May 31, 2011
    Publication date: April 25, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Ranjan Deepak Deshmukh, Ralf Kuegler, Joerg J. Schneider, Rudolf Hoffmann
  • Publication number: 20130102608
    Abstract: The present invention relates to novel bipyridyl derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
    Type: Application
    Filed: June 7, 2011
    Publication date: April 25, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Guenter Hoelzemann, Dieter Dorsch, Alfred Jonczyk, Christiane Amendt, Frank Zenke
  • Publication number: 20130102603
    Abstract: The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.
    Type: Application
    Filed: May 31, 2011
    Publication date: April 25, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Dieter Dorsch, Alfred Jonczyk, Guenter Hoelzemann, Christiane Amendt, Frank Zenke