Patents Assigned to Merck Patent GmbH
  • Patent number: 7345301
    Abstract: The present invention describes new types of material mixtures composed of at least two substances, one serving as a matrix material and the other being an emission material capable of emission, the latter comprising at least one element of atomic number greater than 20, and the use thereof in organic electronic components such as electroluminescent elements and displays.
    Type: Grant
    Filed: April 13, 2004
    Date of Patent: March 18, 2008
    Assignee: Merck Patent GmbH
    Inventors: Anja Gerhard, Horst Vestweber, Philipp Stössel, Susanne Heun, Hubert Spreitzer
  • Patent number: 7344762
    Abstract: The invention relates to the use of a printable polymerisable liquid crystal material as printable system for the preparation of polymers and pigments, to printable polymerisable liquid crystal materials and pigments and polymers prepared thereof, and to the use of the printable materials, pigments and polymers in optical, electrooptical, semiconductor and electronic applications and as birefringent and optically variable markings for decorative, security, authentification or identification applications.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: March 18, 2008
    Assignee: Merck Patent GmbH
    Inventors: Robert Hammond-Smith, John Patrick, Rodney Riddle
  • Patent number: 7339031
    Abstract: The invention provides modified forms of bouganin protein having biological activity and a reduced propensity to activate human T cells as compared to the non-modified bouganin protein. The invention also provides T-cell epitope peptides of bouganin, and modified T-cell epitope peptides of bouganin which have a reduced propensity to activate human T cells as compared to the non-modified T-cell epitope peptide. The invention also provides cytotoxins having the having a ligand that binds to a cancer cells attached to the modified bouganin proteins. Also provided are methods of inhibiting or destroying mammalian cancer cells using the cytotoxins of the invention and pharmaceutical compositions for treating human cancer.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: March 4, 2008
    Assignee: Merck Patent GmbH
    Inventors: Matthew Baker, Francis J. Carr, Koen Hellendoorn, Jeannick Cizeau, Glen Christopher MacDonald, Joycelyn Entwistle, Denis Georges Bosc, Nicholas Ronald Glover
  • Patent number: 7335403
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy, which comprises at least one compound of the formula (I) in which R0, R1, A1, Z1 and m have the meanings indicated in Claim 1, and to the use thereof for an active-matrix display based on the ECB, PALC or IPS effect.
    Type: Grant
    Filed: November 5, 2003
    Date of Patent: February 26, 2008
    Assignee: Merck Patent GmbH
    Inventors: Melanie Klasen-Memmer, Matthias Bremer, Lars Lietzau
  • Publication number: 20080045478
    Abstract: The invention relates to complexes of specific flavonoid derivatives, to preparations containing derivatives of this type, to corresponding methods for producing said derivatives or preparations containing the latter and to the use of the latter, in particular for the care, preservation or improvement of the general condition of the skin or hair.
    Type: Application
    Filed: July 12, 2005
    Publication date: February 21, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Herwig Buchholz, Ralf Rosskopf, Christophe Carola
  • Publication number: 20080045483
    Abstract: The invention relates to compounds of general formula (1): in which R1, R2, R3, R4, R5, A, B, D and E are as defined in Claim 1, and also to the preparation process therefor and the therapeutic use thereof. These compounds can be used in the treatment of pathologies associated with hyperglycaemia.
    Type: Application
    Filed: June 1, 2005
    Publication date: February 21, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Gerard Moinet, Gerard Botton, Micheline Gergoat
  • Publication number: 20080045529
    Abstract: The invention relates to compounds of formula (I), wherein R1, R2, R3, R4, X and n have the meanings cited in claim (1). Said compounds are inhibitors of tyrosinkinases, especially TIE-2, and Raf-Kinases and can be used, for example, in the treatment of tumours.
    Type: Application
    Filed: October 14, 2004
    Publication date: February 21, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Hans-Michael Eggenweiler, Alfred Jonczyk, Gerhard Barnickel, Wilfried Rautenberg, Helga Drosdat, Arne Sutter
  • Patent number: 7332369
    Abstract: A method for forming an organic electronic device, which method comprises the steps of: a) forming a negative image of a desired pattern on a substrate or device layer with a lift-off ink; b) coating a first device layer to be patterned on top of the negative image; c) coating one or more further device layers to be patterned on top of the first device layer to be patterned; and d) removing the lift-off ink and unwanted portions of the device layers above it, thereby leaving the desired pattern of device layers. The method allows the formation of a device structure wherein the device layers to be patterned are self-aligned. The method enables a multiplicity of layers to be patterned in a single set of printing and lift-off steps using one pattern which ensures the excellent vertical alignment of edges, which would be difficult to achieve by direct printing. Horizontal alignment can also be achieved. The size of the device features can be reduced below the actual printing resolution.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: February 19, 2008
    Assignee: Merck Patent GmbH
    Inventors: Janos Veres, Simon Dominic Ogier, Stephen George Yeates
  • Publication number: 20080038213
    Abstract: The invention relates to compounds of the formula (I) or (II), to compositions which comprise such compounds, to corresponding processes for the preparation of the compounds or the compositions comprising same, and to the use thereof as light-protection filters.
    Type: Application
    Filed: July 27, 2005
    Publication date: February 14, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Christophe Carola, Frank Pfluecker, Herwig Buchholz, Hansjurgen Driller, Hans Neunhoeffer, Evgeniy Blyumin
  • Patent number: 7329896
    Abstract: The invention relates to polymerizable charge transport compounds, their use as semiconductors or charge transport materials, in optical, electrooptical or electronic devices like for example organic field effect transistors (FET or OFET) for thin film transistor liquid crystal displays and integrated circuit devices such as RFID tags, electroluminescent devices in flat panel displays, and in plotovoltaic and sensor devices, and to a field effect transistor, light emitting device or ID tag comprising the polymerisable charge transport compounds.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: February 12, 2008
    Assignee: Merck Patent GmbH
    Inventors: Steven Tierney, Mark Goulding, Louise Farrand, Mark Giles, Marcus Thompson, Maxim Shkunov, David Sparrowe, Iain McCulloch, Martin Heeney
  • Publication number: 20080027220
    Abstract: The invention relates to novel metal complexes. Said compounds can be used as functional materials in a series of different types of applications that can be attributed in the broadest sense to the electronics industry The inventive compounds are defined by formula (1).
    Type: Application
    Filed: July 14, 2005
    Publication date: January 31, 2008
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stossel, Esther Breuning
  • Publication number: 20080026470
    Abstract: The invention relates to a device which is in the form of a test strip, and to a method for quickly determining the content of polyphenoles in must and wine. Detection occurs after the method for folin and ciocalteau by means of a test strip which is impregnated with the reagent, which is produced in a method wherein at least sodium, sodium molybdate and phosphoric acid is mixed and heated.
    Type: Application
    Filed: July 30, 2005
    Publication date: January 31, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Dieter Tanzer, Uwe Kraetschmer
  • Publication number: 20080027140
    Abstract: The present invention relates to combinations of serotonin reuptake inhibitors and imidazoline I2 agonists as separate chemical units or both properties combined in a single molecule and to the use thereof for the preparation of medicaments for the treatment of depression, obsessive-compulsive disorders (OCDs), obsessive-compulsive spectrum disorders (OCSDs) and other anxiety states.
    Type: Application
    Filed: December 15, 2004
    Publication date: January 31, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Gerd Bartoszyk, Christoph Van Amsterdam, Henning Boettcher, Christoph Seyfried
  • Publication number: 20080026229
    Abstract: The invention relates to the improvement of organic electronic devices, especially organic electroluminescence devices, to which end inclusion compounds are used, especially as charge injection materials and/or charge transporting materials.
    Type: Application
    Filed: May 3, 2005
    Publication date: January 31, 2008
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stossel, Anja Gerhard, Horst Vestweber
  • Publication number: 20080025947
    Abstract: Methods directed to enhancing the effectiveness of IL-2 in stimulating the immune system is disclosed. According to one method, an antagonist directed against the CD25 subunit of the high-affinity IL-2 receptor complex is administered in conjunction with IL-2. The CD25 antagonist may be an anti-CD25 antibody. According to another method, an anti-IL-2 antibody is administered in conjunction with IL-2. In another method, a mutant IL-2 with diminished ability to bind the CD25 subunit of the high-affinity IL-2 receptor complex is administered. In another method, an CD4 antagonist is administered in conjunction with IL-2 in order to stimulate the immune system.
    Type: Application
    Filed: July 5, 2007
    Publication date: January 31, 2008
    Applicant: Merck Patent GmbH
    Inventors: Stephen Gillies, Kin-Ming Lo, Yan Lan
  • Patent number: 7318862
    Abstract: The present invention relates to stabilized BiOCl pigments in which BiOCl is coated with one or more polymers and oxides, oxide hydrates or hydroxides of silicon, to a process for the production of the stabilized BiOCl pigments, and to the use thereof.
    Type: Grant
    Filed: May 10, 2005
    Date of Patent: January 15, 2008
    Assignee: Merck Patent GmbH
    Inventors: Griessmann Carsten, Rathschlag Thomas
  • Patent number: 7316830
    Abstract: The invention relates to liquid-crystalline phenol esters of the formula I in which R, A1, Z1, m, L and Y are as defined in Claim 1, to liquid-crystalline media comprising at least one phenol ester of the formula I, and to electro-optical displays containing such a liquid-crystalline medium.
    Type: Grant
    Filed: August 24, 2006
    Date of Patent: January 8, 2008
    Assignee: Merck Patent GmbH
    Inventors: Volker Reiffenrath, Michael Heckmeier, Eike Poetsch, Joachim Krause, Werner Binder, Brigitte Schuler, Achim Götz
  • Patent number: 7314943
    Abstract: The invention relates to pyran derivatives of formula I and processes and intermediates for their preparation and derivatisation, and the use thereof in liquid-crystalline media.
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: January 1, 2008
    Assignee: Merck Patent GmbH
    Inventors: Eike Poetsch, Volker Meyer, Werner Binder, Michael Heckmeier, Georg Luessem, Stephan Guertler
  • Publication number: 20070299065
    Abstract: Novel compounds of the formula (I), in which T, E, R, R?, R?, R1, R2 and R2? have the meanings indicated in patent Claim 1, are suitable as antidiabetics.
    Type: Application
    Filed: November 7, 2005
    Publication date: December 27, 2007
    Applicant: MERCK PATENT GMBH
    Inventors: Werner Mederski, Christoph Van Amsterdam, Christa Burger, Hartmut Greiner
  • Patent number: 7312328
    Abstract: This invention relates to compounds of the formula (I) in which R1, R2, R3, X and Q are as defined above and their use as PDE IV inhibitors.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: December 25, 2007
    Assignee: Merck Patent GmbH
    Inventors: Hans-Michael Eggenweiler, Michael Wolf, Norbert Beier, Joachim Leibrock, Michael Gassen, Thomas Ehring