Abstract: A liquid-crystalline medium containing one or more compounds of formula IA, and the use thereof in an active-matrix display, in particular in a VA, IPS, U-IPS, FFS, UB-FFS, SA-VA, SA-FFS, PS-VA, PS-OCB, PS-IPS, PS-FFS, PS-UB-FFS, PS-posi-VA, PS-TN, polymer stabilised SA-VA or polymer stabilised SA-FFS display.
Type:
Grant
Filed:
September 26, 2019
Date of Patent:
June 28, 2022
Assignee:
Merck Patent GmbH
Inventors:
Martin Engel, Sebastian Hofmeyer, Christoph Marten, Lars Lietzau
Abstract: This invention relates generally to bifunctional molecules including (a) a TGF?RII or fragment thereof capable of binding TGF? and (b) an antibody, or antigen binding fragment thereof, that binds to an immune checkpoint protein, such as Programmed Death Ligand 1 (PD-L1), uses of such molecules (e.g., for treating cancer), and methods of making such molecules.
Abstract: The present disclosure relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.
Type:
Application
Filed:
February 24, 2022
Publication date:
June 23, 2022
Applicant:
Merck Patent GmbH
Inventors:
Heidi ROMMELAERE, Joost Alexander KOLKMAN, Michael John Scott SAUNDERS, Ann UNION, Yolande CHVATCHKO, Amanda E.I. PROUDFOOT, Alain VICARI, Denis BRUNIQUEL, Laurent CHEVALET, Olivier LEGER
Abstract: The present invention relates to a composition consisting essentially of an alkylbenzenesulfonic acid having structure (I) (wherein n is an integer from 0 to 16); a solvent which is either selected from the group consisting of solvents having structures (II), (wherein R is selected from the group consisting of —(—O—CH2—CH2—)n—OH, —OH, —O—C(?O)—CH3, wherein n? is equal to 1, 2, 3, or 4), a solvent having structure (III), a solvent having structure (IV), and a solvent having structure (V), or a solvent mixture, of at least two solvents selected from this group. In another embodiment, the composition also consists of, additionally, a surfactant component. This invention also relates to using either of these compositions to remove a patterned photoresist from a substrate.
Abstract: The present invention relates to pyrazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (FSHR).
Type:
Grant
Filed:
August 22, 2018
Date of Patent:
June 21, 2022
Assignee:
Merck Patent GmbH
Inventors:
Henry Yu, Marianne Donnelly, Ngan Nguyen, Xuliang Jiang
Abstract: The present invention provides a resist underlayer forming composition, which is well in heat resistance and gap filling. Further, the present invention provides methods of manufacturing a resist underlayer and semiconductor device using it. [Means for Solution] A composition comprising a allyloxy derivative having a specific group and a solvent, and methods of manufacturing a resist underlayer and semiconductor device using it.
Abstract: The present invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices, and to electronic devices which comprise these compounds.
Abstract: The present invention relates to a process for the preparation of a conjugate, comprising a biological molecule, an enzymatic tag, a hydrophilic spacer, a linker and a lipophilic moiety using enzymatic coupling.
Type:
Application
Filed:
March 10, 2020
Publication date:
June 16, 2022
Applicant:
MERCK PATENT GMBH
Inventors:
Steffen WOELL, Stefan SCHILLER, Simon GEISSLER
Abstract: A liquid-crystalline medium, preferably having a nematic phase and dielectric anisotropy of 0.5 or more, which comprises one or more compounds of each of formulae T and L in which the parameters have the meanings given in the claims and in the text. The use thereof in an electro-optical display, particularly in an active-matrix display based on the IPS or FFS effect, to displays of this type which contain a liquid-crystalline medium of this type. Also, the compounds of formulae T and L and their use for the improvement of the transmission and/or response times of a liquid-crystalline medium which comprises one or more additional mesogenic compounds.
Type:
Grant
Filed:
December 18, 2020
Date of Patent:
June 14, 2022
Assignee:
Merck Patent GmbH
Inventors:
Atsutaka Manabe, Constanze Brocke, Sebastian Hofmeyer
Abstract: In order to provide a novel ?-conjugated compound capable of increasing the light-emission efficiency of an organic electroluminescence element, for example, this ?-conjugated compound has a structure indicated by general formula (1). (In general formula (1): Z1-Z6 each independently indicate a hydrogen atom, a deuterium atom, an electron-donating group D, or an electron-withdrawing group A; at least out of two among Z1-Z6 is an electron-donating group D and the other is an electron-withdrawing group A; and at least one ortho position combination Z1 and Z2, Z2 and Z3, Z3 and Z4, Z4 and Z5, Z5 and Z6, or Z6 and Z1 among Z1-Z6 is one combination out of an electron-donating group D and an electron-donating group D, an electron-withdrawing group A and an electron-withdrawing group A, or an electron-donating group D and an electron-withdrawing group A.
Abstract: Polyfluorinated additives for use as components in liquid-crystal mixtures. Liquid-crystal mixtures which comprise these compounds. And liquid-crystal displays based on these liquid-crystal mixtures.
Type:
Grant
Filed:
December 5, 2017
Date of Patent:
June 14, 2022
Assignee:
MERCK PATENT GMBH
Inventors:
Peer Kirsch, Qiong Tong, Helga Haas, Kaja Christina Deing, Christoph Marten, Andreas Pohle, Reiner Friedrich
Abstract: The present invention relates to novel siloxane oligomer and polymers and crosslinkable compositions, which may be used for the preparation of dielectric materials having excellent barrier, passivation and/or planarization properties. There is also provided a monomer composition from which the siloxane oligomers or polymers may be obtained and a method for preparing said siloxane oligomers or polymers. Beyond that, the present invention relates to a manufacturing method for preparing a microelectronic structure, wherein a crosslinkable composition is applied to a surface of a substrate and then cured, and to an electronic device comprising a microelectronic structure which is obtained by said manufacturing method.
Type:
Application
Filed:
March 6, 2020
Publication date:
June 9, 2022
Applicant:
Merck Patent GmbH
Inventors:
Karsten KOPPE, Jens EICHHORN, Ben JEFFERY, Alex DAVIS, William MITCHELL, Pawel MISKIEWICZ, Toshiaki NONAKA
Abstract: A polymerizable LC material comprising one or more reactive mesogenic compounds, one or more chiral compounds and a block copolymer that comprises at least one polyfluorooxetane block bonded to a polyether block, said polyfluorooxetane block having a repeating unit of the formula Further, a method for its preparation, a polymer film obtainable from a corresponding polymerizable LC material, a method of preparation of such polymer film, and the use of such polymer film and said polymerizable LC material in optical, electro-optical, decorative or security devices.
Type:
Application
Filed:
December 3, 2021
Publication date:
June 9, 2022
Applicant:
Merck Patent GmbH
Inventors:
Stephen Mulcahy, Owain Llyr Parri, Sarabjot Kaur
Abstract: A double layer liquid crystal device comprises a first and a second layer with orthogonal or crossed alignment of the liquid crystal phase of the two layers, in which the first and second layer have first and second alignment aids comprised of a polymerized or polymerizable molecular compound. The layers are aligned by UV photoalignment and vertical self-alignment by the aid of suitable additives.
Type:
Grant
Filed:
September 25, 2020
Date of Patent:
June 7, 2022
Assignee:
Merck Patent GmbH
Inventors:
Joseph Sargent, Sarabjot Kaur, Simon Siemianowski, Izumi Saito
Abstract: The invention relates to a compound of formula I, wherein R11, R21, A11, A, Z, X11, X21, Y11, Y12, Sp11, Sp21, o and p have one of the meanings as given in claim 1. The invention further relates to method of production of a compound of formula I, to the use of said compounds in LC media and to LC media comprising one or more compounds of formula I. Further, the invention relates to a method of production of such LC media, to the use of such media in LC devices, and to LC device comprising a LC medium according to the present invention. The present invention further relates to a process for the fabrication such liquid crystal display and to the use of the liquid crystal mixtures according to the invention for the fabrication of such liquid crystal display.
Type:
Grant
Filed:
April 18, 2019
Date of Patent:
June 7, 2022
Assignee:
Merck Patent GmbH
Inventors:
Lars Lietzau, Simon Siemianowski, Izumi Saito
Abstract: The present invention relates to compounds comprising a heterocyclic group substituted with a fluoranthene group and a particular aromatic or heteroaromatic group. The compounds are suitable for use in electronic devices, in particular organic electroluminescent devices, comprising these compounds. In some embodiments, the compounds are used as matrix materials for phosphorescent or fluorescent emitters as well as a hole-blocking or an electron-transport layer.
Type:
Grant
Filed:
October 6, 2016
Date of Patent:
June 7, 2022
Assignee:
MERCK PATENT GMBH
Inventors:
Amir Hossain Parham, Tobias Grossmann, Jonas Valentin Kroeber
Abstract: The present invention describes dibenzofuran compounds substituted by carbazole compounds, especially for use as triplet matrix materials in organic electroluminescent devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.
Type:
Grant
Filed:
November 6, 2017
Date of Patent:
May 31, 2022
Assignee:
MERCK PATENT GMBH
Inventors:
Amir Parham, Thomas Eberle, Anja Jatsch, Tobias Grossmann, Jonas Kroeber, Dominik Joosten, Caroline Wern