Abstract: The invention relates to a polymerisable LC medium with flat, negative or positive optical dispersion, a polymer film with flat, negative or positive optical dispersion obtainable from such a material, and the use of the polymerisable LC medium and polymer film in optical, electro optical, electronic, semiconducting or luminescent components or devices.
Type:
Application
Filed:
August 13, 2018
Publication date:
November 19, 2020
Applicant:
Merck Patent GmbH
Inventors:
Eduardo BELTRAN GRACIA, Kevin ADLEM, Naomi WEARE, Hassan NOROUZI-ARASI
Abstract: The present invention relates to formulations containing at least one organic functional material and at least a first organic solvent, wherein said first organic solvent contains at least one norbornene group as well as to electronic devices prepared by using these formulations.
Type:
Grant
Filed:
January 17, 2017
Date of Patent:
November 17, 2020
Assignee:
Merck Patent GmbH
Inventors:
Li Wei Tan, Pawel Miskiewicz, Philip Edward May, Daniel Walker
Abstract: The invention relates to quinoxaline derivatives of the general formula I, and the use of the compounds of the present invention for the treatment and/or prevention of hyperproliferative or infectious diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.
Type:
Application
Filed:
August 20, 2018
Publication date:
November 12, 2020
Applicant:
MERCK PATENT GMBH
Inventors:
Eva-Maria TANZER, Kai SCHIEMANN, Markus KLEIN
Abstract: ?-amino boronic acid derivatives are useful for inhibiting the activity of immunoproteasome (LMP7) and for the treatment and/or prevention of medical conditions affected by immunoproteasome activity such as inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer.
Type:
Application
Filed:
August 21, 2018
Publication date:
November 12, 2020
Applicant:
Merck Patent GmbH
Inventors:
Markus Klein, Oliver Schadt, Christina Esdar
Abstract: The present disclosure relates to amino acid sequences that are directed against (as defined herein) any of IL-17A, IL-17F and/or IL-17A/F including combinations thereof, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.
Type:
Grant
Filed:
June 7, 2018
Date of Patent:
November 10, 2020
Assignee:
Merck Patent GmbH
Inventors:
Heidi Rommelaere, Joost Alexander Kolkman, Michael John Scott Saunders, Ann Union, Yolande Chvatchko, Amanda E. I. Proudfoot, Alain Vicari, Denis Bruniquel, Laurent Chevalet, Olivier Leger
Abstract: Compounds of the formula Ia or of the formula Ib in which X, Y, R1 and R2 have the meanings indicated in Claim 1, are inhibitors of pyruvate dehydrogenase kinase (PDHK), and can be employed, inter alia, for the treatment of diseases such as cancer.
Abstract: The present invention relates to novel compounds, particularly to compounds comprising a photoactive unit, said novel compounds being particularly suitable for ophthalmic devices as well as to ophthalmic devices comprising such compounds.
Type:
Grant
Filed:
August 3, 2016
Date of Patent:
November 10, 2020
Assignee:
Merck Patent GmbH
Inventors:
Lars Dobelmann-Mara, Stefan Riedmueller, Martin Schraub
Abstract: The present invention relates to a directly compressible composition for the production of tablets which comprise fine-grained polyvinyl alcohols (PVAs) and fine-grained microcrystalline celluloses (MCCs) in a co-mixture. The present invention also relates to the use of this mixture and to a process for the preparation thereof.
Type:
Grant
Filed:
July 11, 2018
Date of Patent:
November 10, 2020
Assignee:
Merck Patent GmbH
Inventors:
Roberto Ognibene, Finn Bauer, Thorsten Wedel, Guenter Moddelmog
Abstract: Liquid-crystalline media comprising one or more compounds of formula T as defined in claim 1, and high-frequency components comprising these media, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, tunable filters, tunable metamaterial structures, and electronic beam steering antennas, e.g. phased array antennas.
Abstract: The present invention relates to laser-markable polymers and coatings which are distinguished by the fact that they comprise tin/antimony oxide-coated spherical TiO2 particles of defined particle size as laser additive.
Abstract: The present invention relates to interference pigments based on transparent, low-refractive-index, flake-form substrates which have a high-refractive-index coating consisting of TiO2 having a layer thickness of 20-200 nm and optionally an outer protective layer, and to the use thereof in paints, coatings, printing inks, security printing inks, plastics, button pastes, ceramic materials, glasses, for seed coloring, as dopants in the laser marking of plastics and papers, as additive for the laser welding of plastics, as additive for coloring in the foods and pharmaceuticals sectors, and in cosmetic formulations and for the preparation of pigment compositions and dry preparations.
Type:
Grant
Filed:
March 31, 2016
Date of Patent:
November 3, 2020
Assignee:
Merck Patent GmbH
Inventors:
Christoph Schmidt, Tanja Delp, Sabine Schoen
Abstract: The present invention relates to a process for the production of virtual three-dimensional patterns in mouldings, in particular to an injection-moulding process for the production of mouldings having a virtual three-dimensional pattern which is formed by flake-form effect pigments, to the mouldings produced by means of this process, and to the use thereof, in particular for decorative purposes.
Abstract: The invention relates to a method for printing a surface (2) with a fluid which contains an organic semiconductor material. The fluid is transported from a storage container (7) through a supply line (5) to a printing head (3), which can be moved over the surface (2), and printed onto the surface (2) by the printing head (3). At least one part of the fluid which is transported through the supply line (5) to the printing head (3) is returned to the storage container (7) via a return line (6), wherein a fluid circuit is formed, and the fluid in the fluid circuit flows through a cleaning device (12) with which the fluid is cleaned. The fluid returned to the storage container (7) flows around and surrounds the fluid being transported in the supply line (5) to the printing head (3) at least in some regions.
Type:
Grant
Filed:
October 23, 2015
Date of Patent:
November 3, 2020
Assignee:
Merck Patent GmbH
Inventors:
Guenter Hauke, Edgar Boehm, Volker Hilarius
Abstract: A method for electrically driving a switchable optical element is provided wherein the state of a liquid-crystalline medium is controlled by an applied electric field. The provided method comprises at least one of a) switching from a scattering state to a clear state, b) switching from a clear state to a scattering state, c) holding a scattering state.
Abstract: The invention relates to a liquid-crystalline medium, in particular based on a mixture of polar compounds, and to the use thereof for an active-matrix display, in particular based on the VA, SA-VA, IPS, PS-IPS, FFS, PS-FFS, UB-FFS or PS-UB-FFS effect.
Type:
Application
Filed:
April 27, 2020
Publication date:
October 29, 2020
Applicant:
MERCK PATENT GMBH
Inventors:
Su-Young KIM, Chang-Suk CHOI, Jeong-Hee SUNG, Ming Chou WU, Sang-Kyu LEE
Abstract: The present invention relates to effect pigments which are based on flake-form substrates having a circular form factor of 1.2-2 and are coated with at least one high-refractive-index layer, and to the use thereof, inter alia in paints, coatings, printing inks, plastics and in cosmetic formulations.
Type:
Application
Filed:
July 6, 2020
Publication date:
October 29, 2020
Applicant:
MERCK PATENT GMBH
Inventors:
Gerhard PFAFF, Stephanie ANDES, Klaus AMBROSIUS, Ralf PETRY, Michael ROESLER, Sabine SCHOEN
Abstract: Device for controlling transmission of radiation, comprises a first substrate comprising a first conductive layer; a second substrate comprising a second conductive layer; an active layer positioned between the first and second conductive layers for controlling the transmission of radiation by altering its light transmissivity dependent on a voltage applied to the first and second conductive layers; a first contact providing a first electrical connection to the first conductive layer; a first portion of an adhesive or solder for attaching a first proximal end of the first contact to the first conductive layer; a second contact providing a second electrical connection to the second conductive layer; and a second portion of adhesive or solder for attaching a second proximal end of the second contact to the first or second conductive layer.
Abstract: The present invention provides compounds of Formula I?, or pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof for treating cellular proliferative disorders (e.g., cancer).
Inventors:
Henry Yu, Michael Clark, Guy Bemis, Michael Boyd, Kishan Chandupatla, Philip Collier, Hongbo Deng, Huijun Dong, Warren Dorsch, Russell R. Hoover, Mac Arthur Johnson, Jr., Shashank Kukarni, Marina Penney, Steven Ronkin, Darin Takemoto, Qing Tang, Nathan D. Waal, Tiansheng Wang, David J. Lauffer, Pan Li