Patents Assigned to Merck Patents GmbH
  • Heteroaryl compounds as IRAK inhibitors and uses thereof
    Patent number: 9790221
    Abstract: The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: October 17, 2017
    Assignee: Merck Patent GmbH
    Inventors: Catherine Jorand-Lebrun, Reinaldo Jones, Annie Cho Won, Ngan Nguyen, Theresa L. Johnson, Lizbeth Celeste Deselm, Kausik Panda
  • DNA sequence, and recombinant preparation of the grass pollen allergen Lol p 4
    Patent number: 9789178
    Abstract: The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilized for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: October 17, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Andreas Nandy, Helmut Fiebig, Oliver Cromwell
  • 3-substituted cyclopentylamine derivatives
    Patent number: 9790216
    Abstract: Compounds of the formula I in which R, W, R1, R4, X1, X2, X3, X4 and q have the meanings indicated in claim 1, are inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: October 17, 2017
    Assignee: Merck Patent GmbH
    Inventors: Christos Tsaklakidis, Wolfgang Staehle, Birgitta Leuthner
  • FULLERENE MIXTURES FOR USE IN ORGANIC ELECTRONIC DEVICES
    Publication number: 20170294585
    Abstract: The invention relates to novel mixtures of substituted fullerenes, to their use in organic electronic (OE) devices, especially organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices comprising these fullerene mixtures.
    Type: Application
    Filed: August 3, 2015
    Publication date: October 12, 2017
    Applicant: MERCK PATENT GMBH
    Inventors: Graham MORSE, Jonathan Henry WILSON, Nicolas BLOUIN, Solene BECHU
  • LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME
    Publication number: 20170292072
    Abstract: A liquid-crystalline medium, preferably having a nematic phase and dielectric anisotropy of 0.5 or more, which has one or more compounds of formula S in which denotes and the other parameters have the meanings given in the text. Also, the use of the medium in an electro-optical display, particularly in an active-matrix display based on the IPS or FFS effect. Displays of this type which contain a liquid-crystalline medium of this type. And use of the compounds of formula S for the improvement of the transmission and/or response times of a liquid-crystalline medium which comprises one or more additional mesogenic compounds.
    Type: Application
    Filed: April 6, 2017
    Publication date: October 12, 2017
    Applicant: MERCK PATENT GMBH
    Inventors: Atsutaka MANABE, Volker REIFFENRATH, Constanze BROCKE, Lars LIETZAU, Brigitte SCHULER
  • PIGMENT MIXTURE
    Publication number: 20170290750
    Abstract: The present invention relates to a pigment mixture based on at least two components A and B, where component A is a mixture of flake-form and spherical substrates which is covered with one or more inorganic layers and/or organic layers, and component B comprises crystalline or amorphous particles selected from the group of the metal oxides, metal hydroxides, metal oxyhalides, Prussian Blue or mixtures thereof, and to the use thereof in paints, coatings, printing inks, security printing inks, plastics, ceramic materials, glasses, in cosmetic formulations, as tracer, as filler and for the preparation of pigment preparations and dry preparations.
    Type: Application
    Filed: April 11, 2017
    Publication date: October 12, 2017
    Applicant: MERCK PATENT GMBH
    Inventors: Lukas HAMM, Nicole HAFERKORN, Marita JEKEL
  • FORMULATIONS AND ELECTRONIC DEVICES
    Publication number: 20170294582
    Abstract: The present invention relates to a formulation comprising at least one organofunctional material which can be employed for the production of functional layers of electronic devices, and at least one aromatic compound. The present invention furthermore relates to electronic devices which are obtainable from these formulations.
    Type: Application
    Filed: August 4, 2015
    Publication date: October 12, 2017
    Applicant: Merck Patent GmbH
    Inventors: PHILIPP STOESSEL, Irina MARTYNOVA, Aurélie LUDEMANN, Edgar KLUGE, Nils KOENEN
  • REACTIVE MESOGEN FORMULATION WITH CONDUCTIVE ADDITIVE
    Publication number: 20170283699
    Abstract: The invention relates to a reactive mesogen (RM) formulation comprising a conductive additive, to a polymer film obtained thereof, and the use of the RM formulation and polymer film in optical or electrooptical components or devices, like optical retardation films for liquid crystal displays (LCDs).
    Type: Application
    Filed: June 22, 2017
    Publication date: October 5, 2017
    Applicant: Merck Patent GmbH
    Inventors: Graham SMITH, Owain Llyr PARRI, Vicki COOK, Georg BERNATZ, David WILKES, Jonathan Henry WILSON, Mark JAMES, Philip Edward MAY
  • Dihydropyrazoles
    Patent number: 9775830
    Abstract: Novel dihydropyrazole derivatives of formula (I) wherein L, R, R3, R4, R5, R6, R7, X1, X2, X3, X4, Y, m and n have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: October 3, 2017
    Assignee: Merck Patent GmbH
    Inventors: Henry Yu, Thomas E. Richardson, Robert James Foglesong, Lizbeth Celeste Deselm, Andreas Goutopoulos
  • Compounds for electronic devices
    Patent number: 9780311
    Abstract: The present invention relates to compounds for use in electronic devices, preferably organic electroluminescent devices. The invention furthermore relates to processes for the preparation of these compounds and to electronic devices comprising these compounds, preferably in a function as matrix materials and/or as electron-transport materials.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: October 3, 2017
    Assignee: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Christof Pflumm, Anja Jatsch
  • Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays
    Patent number: 9776952
    Abstract: The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays having a polymer-stabilized blue phase, and in LC media for LC displays of the PS or PSA type (“polymer sustained” or “polymer sustained alignment”), and to LC media and LC displays comprising these compounds.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: October 3, 2017
    Assignee: Merck Patent GmbH
    Inventors: Axel Jansen, Thorsten Kodek, Helmut Haensel, Erdal Durmaz
  • Compounds having a C—C triple bond
    Patent number: 9777217
    Abstract: Compounds containing at least one C—C triple bond within a chain of at least 3 ring systems which have positive dielectric anisotropy, the use thereof for high-frequency components, liquid-crystalline media containing these compounds, and high-frequency components, in particular antennae, especially for the gigahertz region, containing these media. The liquid-crystalline media serve, for example, for the phase shifting of microwaves for tuneable phased-array antennae.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: October 3, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Christian Jasper, Constanze Brocke, Detlef Pauluth, Volker Reiffenrath, Atsutaka Manabe
  • Auto injector with separate needle injection
    Patent number: 9775948
    Abstract: An auto injector having sequential control of needle insertion and dose injection is disclosed. A syringe with a needle is movably positioned in a housing between a first position in which the needle is accommodated inside the housing and a second position in which the needle protrudes outside the housing. A plunger rod tube has at least one locking member configured to normally lock a plunger rod to the plunger rod tube. A syringe driver applies a force to the syringe to move the syringe together with plunger rod tube, plunger rod and plunger rod driver from the first position to the second position. In the second position, the locking member is unlocked and releases the plunger rod to thereby activate the plunger rod driver to advance the plunger rod in the syringe for delivering of at least one dose of medicament.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: October 3, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Soeren Bechmann, Flemming Madsen, Esben W. Johansen
  • DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF
    Publication number: 20170279048
    Abstract: The present invention relates to organic electronic devices, and more specifically to organic field effect transistors, comprising a dielectric layer that comprises a polycycloolefinic polymer and a diazirine compound.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 28, 2017
    Applicants: PROMERUS, LLC, MERCK PATENT GMBH
    Inventors: LARRY F RHODES, HUGH BURGOON, IRINA AFONINA, TOMAS BACKLUND, AURELIE MORLEY
  • Piperidine urea derivatives
    Patent number: 9770446
    Abstract: Compounds of the formula I in which R1-R3 have the meanings indicated in Claim 1, are inhibitors of Tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: September 26, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Hans-Peter Buchstaller, Dieter Dorsch
  • Materials for electronic devices
    Patent number: 9773979
    Abstract: The present invention relates to a compound of the formula (I), (II) or (III), to the use of the compound in an electronic device, and to an electronic device comprising a compound of the formula (I), (II) or (III). The present invention furthermore relates to a process for the preparation of a compound of the formula (I), (II) or (III) and to a formulation comprising one or more compounds of the formula (I), (II) or (III).
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: September 26, 2017
    Assignee: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Arne Buesing, Christof Pflumm, Teresa Mujica-Fernaud, Philipp Stoessel, Thomas Eberle, Frank Voges
  • Compounds for the inhibition of indoleamine-2,3-dioxygenase
    Patent number: 9771370
    Abstract: The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of IDO, and for the treatment of IDO-related disorders.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: September 26, 2017
    Assignee: Merck Patent GmbH
    Inventor: Brian A. Sherer
  • INDAZOLES
    Publication number: 20170267675
    Abstract: The invention provides novel substituted indazole compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases such as cancer, inflammatory or degenerative diseases.
    Type: Application
    Filed: July 30, 2015
    Publication date: September 21, 2017
    Applicants: Merck Patent GmbH, Cancer Research Technology Ltd.
    Inventors: Kai SCHIEMANN, Aurelie MALLINGER
  • LIQUID CRYSTALLINE MEDIUM
    Publication number: 20170267928
    Abstract: The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (??), which is distinguished by the fact that it has a value for the ratio ?1/?n2 in the range 6-45 with a clearing point of >60° C. and a ?? of ??2.3. Media of this type are particularly suitable for electro-optical displays having active-matrix addressing based on the ECB, PA LCD, FFS or IPS effect.
    Type: Application
    Filed: May 30, 2017
    Publication date: September 21, 2017
    Applicant: Merck Patent GmbH
    Inventors: Melanie KLASEN-MEMMER, Sabine SCHOEN
  • DEVICE FOR REGULATING THE PASSAGE OF ENERGY
    Publication number: 20170267929
    Abstract: The present application relates to a device for regulating the passage of energy from an outside space into an inside space, to compounds, windows and uses of the devices and compounds.
    Type: Application
    Filed: August 10, 2015
    Publication date: September 21, 2017
    Applicant: Merck Patent GmbH
    Inventors: Peer KIRSCH, Susann BECK, Michael JUNGE, Andreas BEYER, Ursula PATWAL