Patents Assigned to Merck Patents GmbH
  • Methods of atomic layer deposition for selective film growth
    Patent number: 11230764
    Abstract: Methods of forming metal-containing films by atomic layer deposition are provided. The methods include delivering a metal-containing complex, a purge gas, and a co-reactant to a first substrate under sufficient conditions such that the metal-containing film selectively grows on at least a portion of the first substrate.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: January 25, 2022
    Assignee: MERCK PATENT GMBH
    Inventors: Jean-Sébastien Lehn, Charles Dezelah, Jacob Woodruff
  • CRYSTALLINE SODIUM SALT OF 5-METHYL-(6S)-TETRAHYDROLIC ACID
    Publication number: 20220016121
    Abstract: The present invention is directed to a crystalline sodium salt of 5-methyl-(6S)-tetrahydrofolic acid wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to sodium is from 1:0.5 to 1:1.5 (in mol/mol) and/or hydrates and/or solvates thereof, as well as, a processes of obtaining the same.
    Type: Application
    Filed: July 28, 2021
    Publication date: January 20, 2022
    Applicant: Merck Patent GmbH
    Inventors: Rudolf MOSER, Viola GROEHN, Fritz BLATTER, Martin SZELAGIEWICZ, Ruth BOEHNI STAMM, Markus RUETTIMANN, Giuseppe LAPADULA
  • METHOD FOR PRODUCING VIRTUAL THREE-DEMENSIONAL PATTERNS IN MOLDED BODIES MADE OF PLASTIC
    Publication number: 20220016816
    Abstract: The present invention relates to a two-step process for the production of virtual three-dimensional patterns in polymeric mouldings with the aid of injection-moulding processes, in particular a process in which a conventional injection-moulding process are combined with a reactive injection-moulding process in a suitable manner in order to obtain polymeric mouldings having a virtual three-dimensional pattern which is visible on one surface and is formed by flake-form effect pigments, and to the polymeric mouldings produced by means of this process and to the use thereof, in particular for decorative purposes.
    Type: Application
    Filed: December 2, 2019
    Publication date: January 20, 2022
    Applicant: MERCK PATENT GMBH
    Inventors: Marc HUNGER, Laurent DELOUX
  • Polymerizable compounds and the use thereof in liquid-crystal displays
    Patent number: 11225606
    Abstract: The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal media comprising them, and to the use of the polymerizable compounds and liquid crystalline media for optical, electro-optical and electronic purposes, in particular in liquid crystalline displays, especially in liquid crystalline displays of the polymer sustained alignment type.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: January 18, 2022
    Assignee: MERCK PATENT GMBH
    Inventors: Qiong Tong, Nico Schwebel, Constanze Brocke, Kaja Deing, Julian Vogt, Elisabeth Meyer
  • Bottom antireflective coating forming composition
    Patent number: 11221558
    Abstract: [Problem to be Solved] To provide a bottom antireflective coating forming composition which can show high etching resistance and can be crosslinked even at a relatively low temperature. Further, to provide a resist pattern manufacturing method and a device manufacturing method using the same. [Solution] The bottom antireflective coating forming composition comprises: a polymer A comprising specific repeating units; a low molecular crosslinking agent having a molecular weight of 100 to 3,000; and a solvent. The resist pattern manufacturing method and the device manufacturing method using the same are also provided.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: January 11, 2022
    Assignee: Merck Patent GmbH
    Inventors: Hiroshi Hitokawa, Tetsumasa Takaichi, Shunji Kawato, Tomohide Katayama
  • Method for reducing the trisulfide level in proteins
    Patent number: 11220668
    Abstract: The present invention relates to the use of sulfocysteine and derivatives thereof as cell culture additives to reduce the trisulfide levels in proteins produced in cell culture.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: January 11, 2022
    Assignee: Merck Patent GmbH
    Inventor: Aline Zimmer
  • Liquid-crystalline medium
    Patent number: 11214736
    Abstract: Compounds of the formula I, liquid-crystalline media which contain at least one compound of the formula I and electro-optical displays which contain the LC mixtures, especially for the self-aligning VA, PSA, PS-VA, PVA, MVA, PM-VA, HT-VA or VA-IPS mode in which R1, R2, ring A1, Z1, Z2, Sp, P, L1, L2, r1, r2, r3, m, n, p1 and p2 have the meanings indicated above.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: January 4, 2022
    Assignee: Merck Patent GmbH
    Inventors: Graziano Archetti, Elena Neumann, Rocco Fortte, Timo Uebel, Helmut Haensel, Kristin Mueller
  • DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES
    Publication number: 20210403810
    Abstract: The present invention relates to a compound of the general formula I in which the occurring groups and parameters have the meanings indicated in claim 1, to the use thereof in liquid-crystalline or mesogenic media and to liquid-crystalline or mesogenic media comprising these derivatives.
    Type: Application
    Filed: October 28, 2019
    Publication date: December 30, 2021
    Applicant: MERCK PATENT GMBH
    Inventors: Matthias BREMER, Constanze BROCKE, Atsutaka MANABE, Sven LAUT
  • METHOD FOR INACTIVATING A VIRUS ON A SURFACE
    Publication number: 20210402017
    Abstract: The present invention is related to a method for inactivating a virus on a surface, especially in relation to a SARS-CoV-2 virus, to a composition capable of inactivating a virus on a surface as well as to the use of such a composition for the inactivation of a virus on a surface.
    Type: Application
    Filed: June 24, 2021
    Publication date: December 30, 2021
    Applicant: MERCK PATENT GMBH
    Inventors: Howard EPSTEIN, Qinyun PENG, Bettina MAGSAAM, Heike SCHUCHMANN, Paul NEWCOMB, Jutta Zur LAGE
  • Liquid-crystalline compounds
    Patent number: 11208595
    Abstract: Compounds of the formula I, in which Y1 denotes —O— or —CH2—, and the groups R1, L1 to L6 and X1 have the meanings indicated in claim 1. A process for the preparation thereof, and liquid-crystalline media comprising at least one compound of the formula I and electro-optical displays containing a liquid-crystalline medium this type. The compounds of the formula I include, as structural element, a combination of a 1,4-substituted cyclohexene ring besides a dioxane or tetrahydropyran ring and a substituted biphenyl group.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: December 28, 2021
    Assignee: Merck Patent GmbH
    Inventors: Constanze Brocke, Katharina Linke, Sven Christian Laut
  • Formulations with a low content of phenol type impurities
    Patent number: 11211557
    Abstract: The present invention relates to formulations comprising at least one organic semiconductor and at least one organic solvent, characterized in that the formulation contains less than 100 ppm of phenole type impurities, to their use for the preparation of electronic devices, to methods for preparing electronic or optoelectronic devices using the formulations of the present invention, and to electronic or optoelectronic devices prepared from such methods and formulations.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: December 28, 2021
    Assignee: Merck Patent GmbH
    Inventors: Leticia Garcia Diez, Irina Martynova, Aurélie Ludemann, Hsin-Rong Tseng, Peter Levermore
  • Viscosity reduction of highly concentrated protein formulations
    Patent number: 11207412
    Abstract: The present invention relates to compositions of highly concentrated protein formulations showing reduced viscosity. The contained proteins in the prepared formulations are stabilized against aggregation and denaturation and are thus sufficiently storage-stable until administration to the patient.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: December 28, 2021
    Assignee: Merck Patent GmbH
    Inventors: Martin Zillmann, Alexandra Krog, Raphael Guebeli, Tanja Henzler, Christian Hildebrandt
  • Materials for organic electroluminescent devices
    Patent number: 11208401
    Abstract: The present invention relates to compounds which are suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, comprising these compounds. The compounds have a dibenzofuran, dibenzothiophene or a fluorene group substituted in the 1-position, either directly or through a linking group, to a carbon atom of a heteroaromatic group with one or two nitrogen atoms in a bicyclic 6/6 core, or to a carbon or nitrogen atom of a heteroaromatic group with two nitrogen atoms in a bicyclic 5/6 core and is further substituted with a group selected from dibenzofuran, dibenzothiophene, fluorene or carbazole.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: December 28, 2021
    Assignee: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Anja Jatsch, Thomas Eberle, Tobias Grossmann, Jonas Valentin Kroeber, Lars Dobelmann-Mara
  • Liquid-crystalline medium and high-frequency components comprising same
    Patent number: 11208594
    Abstract: Liquid-crystalline media comprising one or more compounds of formula G and one or more compounds selected from the group of compounds of formulae I, II and III, in which the parameters have the meaning indicated in claim 1, and components comprising these media, are suitable for use in high-frequency technology, in particular, in phase shifters and microwave array antennas.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: December 28, 2021
    Assignee: Merck Patent GmbH
    Inventors: Michael Wittek, Constanze Brocke, Volker Reiffenrath
  • Combination for Treating Cancer
    Publication number: 20210386826
    Abstract: Provided herein are methods and combinations for treating a subject having cancer by administering to the subject a PD-1/PD-L1 axis inhibitor, a CD-122-biased cytokine agonist, and an anti-androgen or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 4, 2019
    Publication date: December 16, 2021
    Applicants: Pfizer Inc., MERCK PATENT GMBH, NEKTAR THERAPEUTICS, Astellas Pharma Inc.
    Inventors: Christoffel Hendrik Boshoff, Rossano Cesari, Cristian Massacesi, Deborah Charych
  • Compounds having fluorene structures
    Patent number: 11201296
    Abstract: The present invention describes fluorene derivatives substituted by electron-transporting groups, especially for use as triplet matrix materials in electronic devices. The invention further relates to a process for preparing the compounds of the invention and to electronic devices comprising these.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: December 14, 2021
    Assignee: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Thomas Eberle, Anja Jatsch, Tobias Grossmann, Jonas Valentin Kroeber
  • 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS
    Publication number: 20210380606
    Abstract: The present invention relates to novel 5-azaindazole derivatives of formula (I), as described and defined herein, and pharmaceutically acceptable salts, solvates and prodrug thereof, as well as pharmaceutical compositions comprising such compounds. The 5-azaindazole derivatives according to the invention have been found to be highly effective dual A2A/A2B adenosine receptor antagonists, and can thus be used as therapeutic agents, particularly in the treatment or prevention of hyperproliferative or infectious diseases or disorders.
    Type: Application
    Filed: October 22, 2019
    Publication date: December 9, 2021
    Applicant: Merck Patent GmbH
    Inventors: Anne-Laure BLAYO, Baptiste MANTEAU, Ismet DORANGE, Stanislas MAYER, Stephan SCHANN, Thomas CATELAIN
  • NANOPARTICLE
    Publication number: 20210380882
    Abstract: The present invention relates to a nanoparticle and a composition comprising a nanoparticle.
    Type: Application
    Filed: October 11, 2019
    Publication date: December 9, 2021
    Applicant: Merck Patent GmbH
    Inventor: Itai LIEBERMAN
  • ADDITIVES FOR PROTEIN FORMULATIONS TO IMPROVE THERMAL STABILITY
    Publication number: 20210379186
    Abstract: The present invention relates to excipients for special protein formulations, which are suitable to improve the thermal stability against denaturation and deactivation. In particular, the present invention relates to additives for thermostabilizing of vaccine formulations.
    Type: Application
    Filed: April 16, 2019
    Publication date: December 9, 2021
    Applicant: MERCK PATENT GMBH
    Inventors: Tobias ROSENKRANZ, Janet SCHACHE
  • Quinoxaline derivatives as adenosine receptor antagonists
    Patent number: 11192899
    Abstract: The invention relates to quinoxaline derivatives of the general formula I, and the use of the compounds of the present invention for the treatment and/or prevention of hyperproliferative or infectious diseases and disorders in mammals, especially humans, and pharmaceutical compositions containing such compound.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: December 7, 2021
    Assignee: MERCK PATENT GMBH
    Inventors: Eva-Maria Tanzer, Kai Schiemann, Markus Klein