Patent number: 6953792
Abstract: The present invention relates compounds of the formula (I): wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of: (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l) and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R?17, R18, R19, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
Type:
Grant
Filed:
May 16, 2001
Date of Patent:
October 11, 2005
Assignees:
Merck Sharp & Dohme Limited, Merck & Co., Inc.
Inventors:
Jose Luis Castro Pineiro, Kevin Dinnell, Jason Matthew Elliot, Gregory John Hollingworth, Duncan Edward Shaw, Christopher John Swain, Lihu Yang