Patents Assigned to MERCK SHARP & DOHME RESEARCH GMBH
  • NAV1.7 BINDERS
    Publication number: 20240002497
    Abstract: Antibodies and antigen-binding fragments thereof that bind the human voltage-gated sodium channel Nav1.7? protein subunit (Nav1.7 binders) are described. In particular embodiments, the Nav1.7 binders comprise a heavy-chain immunoglobulin single variable domain (ISVD or VHH).
    Type: Application
    Filed: November 18, 2021
    Publication date: January 4, 2024
    Applicants: MERCK SHARP & DOHME LLC, MERCK SHARP & DOHME RESEARCH GMBH
    Inventors: Pravien Damitha Abeywickrema, Erik Depla, Bruno Dombrecht, Daniel M. Gorman, Andrea K. Houghton, Robert A. Kastelein, Richard L. Kraus, John Majercak, Kalyan Pande, Sujata Sharma