Patents Assigned to Merck Sharpe & Dohme B.V.
  • Antibodies to human programmed death receptor PD-1
    Patent number: 9834605
    Abstract: Antibodies which block binding of hPD-1 to hPD-L1 or hPD-L2 and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune cell through the PD-1 pathway is also disclosed.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: December 5, 2017
    Assignee: Merck Sharpe & Dohme B.V.
    Inventors: Gregory John Carven, Hans Van Eenenneem, Gradus Johannes Dulos