Abstract: Embodiments of the present invention provide a device, system and method for providing high flow therapy interfaces for use in the treatment of respiratory conditions and in assisted respirations. In an embodiment of the invention, a nasal cannula for delivery of respiratory gases can include at least one nasal insert and at least one flange coupled to the at least one nasal insert where the at least one flange is configured to partially impede the egress of respiratory gasses delivered to an upper airway of a patient is provided. In another embodiment, a flange has a shape selected from the group consisting of a slotted, vented or slitted design and configured to partially impede the egress of respiratory gasses. In yet another embodiment, an oral interface for delivery of high flow therapy to the upper airway of a patient can include a gas diffuser that includes a terminus housing having a plurality of holes to allow the delivery of respiratory gases.

Abstract: Medicine delivery interface for delivery of therapeutic aerosols or gases, including at least one hollow body having at least one nasal aperture defined therein at least one nasal insert tube associated with each nasal aperture of the hollow body is capable of being inserted into a nostril. The interface also may include at least one exhaust aperture having at least one exhaust valve configured to exhaust exhaled gases and configured to block inflow of air through the exhaust aperture and at least one intake aperture.

Abstract: An apparatus for delivering phototherapy includes at least one substrate, at least one emitter mounted on the substrate, and which emits at least two peak wavelengths of light, and an electronic circuit that controls emitter timing. The apparatus is configured as a dressing. A corresponding method includes delivering a first pulse of light to the target tissue from the emitter with a peak wavelength of light, and delivering at least a second pulse of light having a peak wavelength of light that is different from the peak wavelength of the first pulse of light, and the steps define a method of delivering a series of pulse sets of light, and the first and second pulses of light define a pulse set of light. Also disclosed are modular phototherapy units, control of timing of phototherapy by a perfusion detector, and use of long wavelength light for hyperbilirubinemia.