Abstract: The invention relates to the equine GM-CSF, its nucleotide coding sequence and its amino acid sequence, as well as its use as adjuvant in equine vaccination and as non-specific immunity stimulant. The invention also includes compositions containing equine GM-CSF or vectors expressing GM-CSF in vivo.
Type:
Grant
Filed:
June 7, 2000
Date of Patent:
November 11, 2003
Assignees:
Merial Limited, Merial LLC
Inventors:
Michel Bublot, Jennifer Maria Perez, Christine Michèle Pierrette Andreoni
Abstract: Long-acting injectable formulations are formed from a) a therapeutic agent selected from insecticides, acaricides, parasiticides, growth enhancers or oil-soluble NSAIDs, b) hydrogenated castor oil, and c) a hydrophobic carrier comprising i) triacetin, benzyl benzoate, ethyl oleate, or a combination thereof, and ii) acylated monoglycerides, propyl dicaprylates/dicaprates, caprylic/capric acid triglycerides or a combination thereof.