Abstract: Disclosed is a method for identifying a greater risk for developing bronchopulmonary dysplasia (BPD) of a preterm infant. The method comprises obtaining a genomic DNA sample from the preterm infant's mother, genotyping rs2280789 SNP in the RANTES gene, and determining the preterm infant as being at risk of developing BPD if the genotype of the rs2280789 SNP is CC. Also disclosed are a primer pair for genotyping rs2280789 SNP in the RANTES gene, and a method thereof.
Abstract: Disclosed is a method for identifying a greater risk for developing bronchopulmonary dysplasia (BPD) of a preterm infant. The method comprises obtaining a genomic DNA sample from the preterm infant's mother, genotyping rs1800566 SNP in the NQO1 gene, and determining the preterm infant as being at risk of developing BPD if the genotype of the rs1800566 SNP is TT. Also disclosed are a primer pair for genotyping rs1800566 SNP in the NQO1 gene, and a method thereof.
Abstract: Disclosed is a method of identifying a greater risk for developing bronchopulmonary dysplasia (BPD) in a preterm infant. The method comprises obtaining a genomic DNA sample from the preterm infant's mother, identifying the nucleotide of rs2280789 SNP in the RANTES gene and the nucleotide of rs1800566 SNP in the NQO1 gene, and determining the preterm infant as being at risk of developing BPD when the genotype of rs2280789 SNP carries C nucleotide and the genotype of rs1800566 SNP carries T nucleotide.
Abstract: Provided is a method for determining the risk of preterm labor in a pregnant female subject. The method comprises detecting the expression level of one or more markers selected from the group consisting of TMEM200A, TMEM108 and GXYLT2, in a sample derived from the pregnant female subject.
Type:
Application
Filed:
December 5, 2017
Publication date:
June 21, 2018
Applicant:
Meribank Biotech Co., Ltd
Inventors:
Chang-Yo HSUAN, Willie LIN, Wei-Ting LIU
Abstract: Provided is a method for determining the risk of bronchopulmonary dysplasia (BPD) of a preterm infant. The method comprises detecting the expression level of EPHB2 in a primary culture of mesenchymal stem or stromal cells (MSCs) derived from a placenta-related tissue of the infant's mother or umbilical cord blood of the infant.
Type:
Application
Filed:
October 19, 2017
Publication date:
May 31, 2018
Applicant:
Meribank Biotech Co., Ltd.
Inventors:
Chang-Yo Hsuan, Willie Lin, Wei-Ting Liu