Patents Assigned to MERIDIGEN BIOTECH CO., LTD.
  • Publication number: 20190060365
    Abstract: Disclosed is a pharmaceutical composition for treating chronic obstructive pulmonary disease, comprising an effective amount of human mesenchymal stem cells, human serum albumin, and a pharmaceutically acceptable carrier or diluent. Also disclosed is a method for treating chronic obstructive pulmonary disease in a subject in need thereof, the method comprising administering to the subject a pharmaceutical composition comprising an effective amount of human mesenchymal stem cells, human serum albumin, and a pharmaceutically acceptable carrier or diluent.
    Type: Application
    Filed: August 25, 2017
    Publication date: February 28, 2019
    Applicant: Meridigen Biotech Co., Ltd.
    Inventors: Chang-Yo HSUAN, Willie LIN, Yu-Chin SU, Tang-bo Chung WU, Yu-Chieh Wen
  • Publication number: 20190054144
    Abstract: Disclosed is a pharmaceutical composition for treating ischemic stroke, comprising an effective amount of human mesenchymal stem cells, human serum albumin, and a pharmaceutically acceptable carrier or diluent. Also disclosed is a method for treating ischemic stroke in a subject in need thereof, the method comprising administering to the subject a pharmaceutical composition comprising an effective amount of human mesenchymal stem cells, human serum albumin, and a pharmaceutically acceptable carrier or diluent. In addition, a method for promoting secretion of hepatocyte growth factor by human mesenchymal stem cells is disclosed.
    Type: Application
    Filed: August 15, 2017
    Publication date: February 21, 2019
    Applicant: Meridigen Biotech Co., Ltd.
    Inventors: Chang-Yo HSUAN, Willie LIN, Yu-Chin SU, Tang-bo Chung WU
  • Publication number: 20180059109
    Abstract: A method of distinguishing mesenchymal stem cells (MSCs) from fibroblasts is provided. Also provided is a method of increasing a purity of mesenchymal stem cells (MSCs) population in a cell culture. The above-mentioned methods each comprise a step of sorting or isolating the cells by a marker of CD146 from a cell culture derived from a placenta-related tissue. Further provided is a method of assessing purity of mesenchymal stem cells (MSCs) in a cell culture derived from a placenta-related tissue, comprising determining the percentage of cells expressing CD146 in the culture.
    Type: Application
    Filed: December 7, 2016
    Publication date: March 1, 2018
    Applicant: Meridigen Biotech Co., Ltd.
    Inventors: Chang-Yo HSUAN, Willie LIN, Yu-Chin SU, Wei-Ting LIU, Meng-Wei LI, Mao-Kuang DU
  • Patent number: 9470685
    Abstract: A method of distinguishing mesenchymal stem cells (MSCs) in a primary culture of cells derived from a placenta-related tissue is provided. Also provided is a method of increasing the purity of MSC population in a primary culture of cells derived from a placenta-related tissue. Further provided is a method of isolating a MSC population which is more responsive in an inflammatory environment. Said methods each comprise a step of sorting the cells by a marker of EphA2.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: October 18, 2016
    Assignee: MERIDIGEN BIOTECH CO., LTD.
    Inventors: Chang-Yo Hsuan, Wei-Ting Liu, Shih-Pei Shen, Yun Lin, Yuan-Tsung Li, Chia-Chi Chang
  • Publication number: 20160161483
    Abstract: A method of distinguishing mesenchymal stem cells (MSCs) in a primary culture of cells derived from a placenta-related tissue is provided. Also provided is a method of increasing the purity of MSC population in a primary culture of cells derived from a placenta-related tissue. Further provided is a method of isolating a MSC population which is more responsive in an inflammatory environment. Said methods each comprise a step of sorting the cells by a marker of EphA2.
    Type: Application
    Filed: December 5, 2014
    Publication date: June 9, 2016
    Applicant: MERIDIGEN BIOTECH CO., LTD.
    Inventors: Chang-Yo HSUAN, Wei-Ting LIU, Shih-Pei SHEN, Yun LIN, Yuan-Tsung LI, Chia-Chi CHANG