Patents Assigned to Merkus, Franciscus W.H.M.
  • Nasal melatonin composition
    Patent number: 6007834
    Abstract: A pharmaceutical composition for intranasal administration, comprising melatonin and a pharmaceutically acceptable excipient, which is effective to cause the blood plasma melatonin concentration in a human adult, receiving an amount of melatonin in the range of 50-1000 .mu.g and in a single or simultaneous intranasal administration of said composition, to reach at least X pg/ml, within 30 minutes of said administration, wherein X is equal to 5 times the amount of melatonin, expressed in .mu.g, in said single or simultaneous administration.
    Type: Grant
    Filed: March 26, 1998
    Date of Patent: December 28, 1999
    Assignee: Merkus, Franciscus W.H.M.
    Inventor: Franciscus W. H. M. Merkus