Abstract: This invention relates to novel 3-heteroaryl-2-fluoro-1-olefins and their pharmacological use as dopamine beta-hydroxylase DBH inhibitors in the treatment of DBH mediated conditions such as hypertension.
Type:
Grant
Filed:
July 25, 1989
Date of Patent:
January 1, 1991
Assignee:
Merrell Dow Pharmaceutical
Inventors:
James R. McCarthy, Donald P. Matthews, Charlotte L. Barney