Abstract: A spermicidally-active vaginal suppository consisting essentially of a solid water-soluble polymeric material which melts at body temperature, for example, a polyethylene glycol, having dispersed therein minor amounts of a spermicide, for example, p-nonylphenoxypolyethoxyethanol, a foaming agent operative when the suppository is dissolved in aqueous media to generate a foam-forming gas, for example, a mixture of a water-soluble bicarbonate and a solid weak acid, and a foam-stabilizing agent which is characterized by containing a surfactant, which is effective to reduce the surface tension of water to less than 45 dynes per centimeter, for example, sodium lauryl sulfate, and lactalbumin.

Abstract: Novel hypolipidemic nicotinates and related esters, being phenoxy organic compounds, are disclosed, as well as pharmaceutical compositions thereof and method of treating hyperlipidemia therewith.

Abstract: The present application relates to compositions which influence the central nervous system and which are especially useful in the treatment of hyperkinesis and rigidity. These compositions contain as active ingredient 1,3-dimethyl-5-aminoadamantane in the form of the free base or a pharmaceutically-acceptable salt thereof, together with a methylxanthine compound, e.g., caffeine or theophylline, in an amount up to about fifteen milligrams of the methylxanthine compound per each milligram of the 1,3-dimethyl-5-aminoadamantane compound. These compositions are useful in the treatment of central nervous system disorders, particularly of Parkinson's disease, depressions, spasticity, rigidity, hyperkinesis, and the like. The compositions possess unpredictable beneficial properties of a synergistic nature. The application also relates to the treatment of such central nervous system ailments or conditions with a combination of the said two active agents either concurrently or together in the same dosage form or unit.

Abstract: Certain 1,3,5-trisubstituted adamantane compounds having central nervous system activity, especially anti-Parkinsonism activity, method of preparing same, and pharmaceutical compositions thereof, method of influencing the central nervous system therewith.

Abstract: The application discloses a novel improved process for the production of .alpha.-[2-(p-chlorophenoxy)-isobutyl]-.beta.-nicotinoyl glycol ester, a known compound having a lipid-lowering effect, by the reaction of .alpha.-[2-chlorophenoxy)-isobutyryl]-.beta.-ethyl chloride ester with an alkali salt of nicotinic acid, preferably sodium nicotinate, preferably in a high-boiling polar or dipolar aprotic solvent, especially dimethylformamide, most preferably at a temperature of about 120.degree. - 180.degree. C., and most advantageously in refluxing dimethylformamide. An unpredictable increase in yields of the desired product over yields attainable by previously-available processes is thereby obtained.

Abstract: A pair of drums is mounted for rotation about at least substantially parallel axes which are located in a common plane. The drums form with one another an axial gap and bodies or walls are located adjacent to the drums and define with the circumferential walls thereof a first channel section which surrounds the circumference of the drums at least in the region of the gap at one side of the plane, and a second channel section which surrounds the circumference of the drums at least in the region of the gap at the other side of the plane. The channel sections merge with one another in the gap. An arrangement is provided for circulating a treating fluid through the channel sections and into the interior of the respective drums and a feeding arrangement feeds the photographic material into the channel sections so that it sequentially moves through the first and thereupon through the second channel section and becomes treated by contact with the treating fluid.

Abstract: A plurality of strip-shaped material-engaging elements is moved by cranks in a path in which the elements sequentially move towards the material to be transported, engage it, move with it through a predetermined distance, and then release it and recede from the material.

Abstract: A spermicidally-active suppository having advantageous properties comprising spermicide, a water-soluble polyethylene glycol suppository base, foaming agent, and foam-stabilizing agent, having a relatively low percentage by weight of foam-developing agent, wherein the spermicide is in alkylphenoxypolyethoxyethanol, the suppository base comprising about 65 to 85 percent by weight of a water-soluble polyethylene glycol which is meltable at body temperature, and the foaming agent comprising about 10 to 20 percent by weight of a mixture of tartaric acid and sodium bicarbonate, and a method of producing the same, are disclosed.