Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
Type:
Grant
Filed:
December 16, 2021
Date of Patent:
February 4, 2025
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Sudeep Kumar, George Sigal, Michael Tsionsky
Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Type:
Application
Filed:
March 27, 2024
Publication date:
January 16, 2025
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Eli N. Glezer, John Kenten, Galina Nikolenko
Abstract: The specification provides an assay electrode including a composite containing a matrix and a multiplicity of graphene particles dispersed therein.
Type:
Application
Filed:
September 12, 2024
Publication date:
January 2, 2025
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Mark BILLADEAU, Paul FREESE, Alan KISHBAUGH, Gisbert SPIELES, Nicholas FOX-LYON
Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
Abstract: The specification provides an assay electrode including a composite containing a matrix and a multiplicity of graphene particles dispersed therein.
Type:
Grant
Filed:
October 28, 2020
Date of Patent:
November 19, 2024
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Mark Billadeau, Paul Freese, Alan Kishbaugh, Gisbert Spieles, Nicholas Fox-Lyon
Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Type:
Application
Filed:
December 13, 2023
Publication date:
October 31, 2024
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Anahit Aghvanyan, Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko, Martin Stengelin
Abstract: In examples, a method of controlling customer access to an assay system comprises (a) receiving a system identifier; (b) identifying said system identifier, and (c) utilizing information obtained from the system identifier to perform one or more operations selected from: (i) enabling full access to said system and/or a consumable used in said system; (ii) enabling partial access to said system and/or a consumable used in said system; or (iii) denying access to said system and/or a consumable used in said system.
Type:
Application
Filed:
March 11, 2024
Publication date:
October 31, 2024
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Xinri CONG, Jerome JACKSON, Carl STEVENS, Michael VOCK, Jacob N. WOHLSTADTER
Abstract: The disclosure is directed to a package for containing a plurality of substantially rectangular assay plates, each plate having a peripheral flange. In one embodiment, the package comprises a cavity having extending therein one or more sloped buttress elements spaced across at least a portion of a top corner, and one or more adjacent protrusions extending from the bottom and at least partially up one or both sidewalls, each set of protrusions forming grooves therebetween into which fit the flanges of respective assay plates. The package can comprise a transparent polymer through which product information located on the assay plates can be read or scanned.
Type:
Grant
Filed:
November 24, 2021
Date of Patent:
October 1, 2024
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Nataliya Lavrykova-Marrain, Jonathan Vu Tran
Abstract: The present invention relates to assays, methods, and kits to assess traumatic brain injury (TBI) in a subject. The present invention also relates to ultrasensitive assays for GFAP, tau, CKBB, IL-1?, IL-2, IL-6, IL-10, IL-22, IP-10, TNF?, TSLP, NFL, and/or NFH.
Abstract: A gripper assembly for a robotic arm includes a gripper finger having a first end and a second end, a gripper pad pivotably coupled to the gripper finger such that the gripper pad is permitted to rotate about a rotational axis relative to the gripper finger, the gripper pad having a pair of sides with one of the sides forming a gripping surface configured to grip an object, and a proximal side located between the pair of sides, and a gripper pad aligner including a pad alignment element coupled to the gripper pad and a finger alignment element coupled to the gripper finger, wherein the pad alignment element is coupled to the finger alignment element and configured to apply an aligning torque to the gripper pad that, when applied, rotates the gripper pad toward a first angular orientation about the rotational axis between the gripper pad and the gripper finger.
Type:
Application
Filed:
February 23, 2024
Publication date:
August 29, 2024
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Slavi MIRTCHEV, Gary I. KRIVOY, Manish KOCHAR, Aaron H. LEIMKUEHLER
Abstract: We describe a detection module useful with an apparatus and/or system for conducting luminescence assays, and a kit, a system, an apparatus, and a method incorporating the detection module.
Type:
Application
Filed:
March 27, 2024
Publication date:
August 8, 2024
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Charles M. CLINTON, Jacob N. WOHLSTADTER
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
Type:
Application
Filed:
January 31, 2024
Publication date:
July 4, 2024
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Charles M. CLINTON, Eli N. GLEZER, Sharon WEST, George SIGAL, Carl STEVENS, Michael L. VOCK
Abstract: Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.
Type:
Grant
Filed:
March 30, 2012
Date of Patent:
June 18, 2024
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Nicholas Anderson, Jeffery Debad, Eli N. Glezer, Sudeep Kumar, Noel Lawrence, Kenneth Page, George Sigal, Sharon West