Patents Assigned to Meso Scale Technologies
  • Detection module alignment system comprising an alignment system for adjusting components of a replaceable detection module after being attached to an apparatus
    Patent number: 11971359
    Abstract: We describe a detection module useful with an apparatus and/or system for conducting luminescence assays, and a kit, a system, an apparatus, and a method incorporating the detection module.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: April 30, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Charles M. Clinton, Jacob N. Wohlstadter
  • Glomerulonephritis biomarkers
    Patent number: 11971418
    Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: April 30, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Galina Nikolenko
  • Biodosimetry panels and methods
    Patent number: 11967410
    Abstract: Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: April 23, 2024
    Assignees: Meso Scale Technologies, LLC, THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
    Inventors: William F Blakely, Eli N. Glezer, John Kenten, Sudeep Kumar, Anu Mathew, Natalia I. Ossetrova, George Sigal
  • Consumable data management
    Patent number: 11960552
    Abstract: In examples, a method of controlling customer access to an assay system comprises (a) receiving a system identifier; (b) identifying said system identifier; and (c) utilizing information obtained from the system identifier to perform one or more operations selected from: (i) enabling full access to said system and/or a consumable used in said system; (ii) enabling partial access to said system and/or a consumable used in said system; or (iii) denying access to said system and/or a consumable used in said system.
    Type: Grant
    Filed: March 17, 2023
    Date of Patent: April 16, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Xinri Cong, Jerome Jackson, Carl Stevens, Michael Vock, Jacob N. Wohlstadter
  • Methods for conducting multiplexed assays
    Patent number: 11951483
    Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: April 9, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Eli N. Glezer, Sudeep Kumar, Pankaj Oberoi, George Sigal, Michael Tsionsky
  • Apparatus for conducting continuous interleaved assaying in a multi-well plate
    Patent number: 11940385
    Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: March 26, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Charles M. Clinton, Eli N. Glezer, Sharon West, George Sigal, Carl Stevens, Michael L. Vock
  • Compositions and methods for carrying out assay measurements
    Patent number: 11927592
    Abstract: The present disclosure provides compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the disclosure relates to an assay composition for detecting luminescence, which comprises an alkyl diethanolamine, for example, N-butyldiethanolamine (BDEA). In emodiments, the assay composition comprises 2-dibutylaminoethanol (BDAE).
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: March 12, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Alexander K. Tucker-Schwartz, George Sigal
  • KIDNEY FUNCTION BIOMARKERS
    Publication number: 20240053364
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 27, 2023
    Publication date: February 15, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko
  • Assay apparatuses, methods, and reagents
    Patent number: 11896979
    Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a multi-well plate assay format.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: February 13, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Gary I. Krivoy, Cecilia Zimmerman, Jules Vandersarl, Sandor Kovacs, Aaron H. Leimkuehler, Leo Tabakin, Jon Willoughby, Manish Kochar, Charles M. Clinton
  • Assay cartridges and methods of using the same
    Patent number: 11896978
    Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: February 13, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Eli N. Glezer, Stephen Higgins, Sandor Kovacs, Sudeep Kumar, Kenneth Page, Kristian Roth, George Sigal
  • PACKAGING FOR MULTIPLEXED ASSAYS
    Publication number: 20240042447
    Abstract: The invention relates to kits and components thereof used in the conduct of solid-phase binding assays.
    Type: Application
    Filed: August 24, 2023
    Publication date: February 8, 2024
    Applicant: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Yihong Claire Lu, Pankaj Oberoi
  • Assay apparatuses, methods and reagents
    Patent number: 11892455
    Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: February 6, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Charles M. Clinton, Eli N. Glezer, Bandele Jeffrey-Coker, Sandor L. Kovacs, Sudeep M. Kumar, George Sigal, Carl Stevens, Michael Vock
  • LUNG CANCER BIOMARKERS
    Publication number: 20240027456
    Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: October 4, 2023
    Publication date: January 25, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko, Martin Stengelin, Srikant Vaithilingam
  • DEVICE HOUSING WITH LIGHTING
    Publication number: 20240027671
    Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.
    Type: Application
    Filed: September 20, 2023
    Publication date: January 25, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Cecilia Zimmerman, Jules VanDersarl
  • DIAGNOSTIC METHODS FOR LIVER DISORDERS
    Publication number: 20230358764
    Abstract: The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or regimen. The invention also relates to assay kits used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 7, 2023
    Publication date: November 9, 2023
    Applicant: Meso Scale Technologies, LLC.
    Inventor: George Sigal
  • Rack and label
    Patent number: D1006251
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 28, 2023
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Jennifer Parker, Manish Kochar, Rodger Darin Osborne
  • Methods for conducting multiplexed assays
    Patent number: RE49774
    Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
    Type: Grant
    Filed: February 11, 2021
    Date of Patent: January 2, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Eli N. Glezer, Sudeep Kumar, Pankaj Oberoi, George Sigal, Michael Tsionsky
  • Cover for reagent rack
    Patent number: D1010857
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: January 9, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Aaron Leimkuehler, Manish Kochar, Jennifer Parker, Nick Sammons, Bandele Jeffrey-Coker
  • Display panel or screen with a graphical user interface
    Patent number: D1012094
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: January 23, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Eli N. Glezer, Michael L. Vock, Kent Johnson
  • Instrument
    Patent number: D1016325
    Type: Grant
    Filed: August 29, 2023
    Date of Patent: February 27, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Rodger Darin Osborne, Sandor Kovacs, Aaron Leimkuehler, Cecilia Zimmerman, Jules VanDersarl