Abstract: The present invention relates to a method of preventing or treating a bone disorder in a mammal, comprising administering to the mammal a therapeutically effective amount of a peptide having ability to modulate lipid metabolism but having no appreciable effect on IGF-1.
Abstract: The present invention provides a method of improving the oral delivery of a parent peptide, comprising the step of linking the parent peptide to an added peptide to form a conjugate which has greater oral bioavailability than the parent molecule alone, the added peptide comprising a balance of hydrophobic and hydrophilic residues as defined herein. Conjugates for use in the method are also provided, as are pharmaceutical compositions comprising the conjugate and methods of treatment using the conjugate or pharmaceutical composition.
Abstract: The invention relates to food and beverage products which are useful in control of obesity. The food or beverage comprises or is made by a transgenic plant or parts thereof comprising a nucleic acid molecule, the nucleic acid molecule encoding a C-terminal growth hormone fragment which has the ability to modulate lipid metabolism. The transgenic plant may be used in a production of a fermented food or beverage product, or may be a part of an edible plant, such as a fruit or vegetable, including but not limited to tomato, banana, and potato.
Type:
Grant
Filed:
November 6, 2000
Date of Patent:
August 29, 2006
Assignee:
Metabolic Pharmaceuticals Limited
Inventors:
Christopher Ian Belyea, Frank Man-Woon Ng, Paul Vaughan