Patents Assigned to Metacrine, Inc.
  • Patent number: 11236071
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: February 1, 2022
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Steven P. Govek, Johnny Y. Nagasawa, Karensa L. Douglas, Andiliy G. Lai
  • Patent number: 11214538
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: January 4, 2022
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Steven P. Govek, Johnny Y. Nagasawa
  • Patent number: 11084817
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: August 10, 2021
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Steven P. Govek, Karensa L. Douglas, Andiliy G. Lai
  • Patent number: 10961198
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: March 30, 2021
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Steven P. Govek, Johnny Y. Nagasawa
  • Patent number: 10927082
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: February 23, 2021
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Stephen P. Govek, Johnny Y. Nagasawa
  • Patent number: 10703712
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: July 7, 2020
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Steven P. Govek, Johnny Y. Nagasawa
  • Patent number: 10626081
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: April 21, 2020
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Steven P. Govek, Johnny Y. Nagasawa
  • Patent number: 10377717
    Abstract: Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with farnesoid X receptor activity.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: August 13, 2019
    Assignee: METACRINE, INC.
    Inventors: Nicholas D. Smith, Steven P. Govek
  • Publication number: 20180050087
    Abstract: Provided herein are methods and compositions for treating lipodystrophy using fibroblast growth factor 1 (FGF-1) compounds.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 22, 2018
    Applicants: Salk Institute for Biological Studies, Metacrine, Inc.
    Inventors: Neil McDonnell, Ronald M. Evans, Michael Downes