Patents Assigned to Metacure N.V.
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Publication number: 20120101874Abstract: Gastric apparatus (18) is provided, including one or more sensors (70, 72, 74), adapted to generate respective sensor signals responsively to a gastrointestinal (GI) tract physiological parameter of a GI tract of a subject, and an implantable control unit (90), comprising a rechargeable battery and a first set of one or more transducers. The implantable control unit (90) is adapted to receive the sensor signals, using one or more of the transducers of the first set, and transmit data responsively to the sensor signals, using one or more of the transducers of the first set. An external control unit (200), including a power source and a second set of one or more transducers, is adapted to drive the power source to inductively transfer energy via one or more transducers of the second set, so as to recharge the battery, and receive the transmitted data, using one or more transducers of the second set.Type: ApplicationFiled: February 15, 2006Publication date: April 26, 2012Applicant: METACURE N.V.Inventors: Shlomo Ben-Haim, Shai Policker, David Prutchi, Benny Rousso, Jason Sholder
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Publication number: 20100228105Abstract: Apparatus is provided, including a control unit (310), adapted to be implanted within a patient (324), and a corkscrew-shaped electrode mount (400), adapted to be implanted in a wall of a stomach of the patient. The corkscrew-shaped electrode mount includes first (404) and second (424) electrodes, at respective sites of the electrode mount, and a controller (420), wirelessly coupled to the control unit. Other embodiments are also described.Type: ApplicationFiled: March 24, 2006Publication date: September 9, 2010Applicant: Metacure N.V.Inventors: Shai Policker, David Prutchi, Ophir Bitton, Benny Rousso, Offer Glasberg
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Publication number: 20090204063Abstract: A method is provided, including physically contacting a gastric implantation site of a stomach via a transluminal approach, physically contacting the site via a transabdominal approach, stabilizing the site, and implanting an electrode at the site based on the physical contact provided by the transluminal and transabdominal approach. Other embodiments are also described.Type: ApplicationFiled: June 4, 2006Publication date: August 13, 2009Applicant: METACURE N.V.Inventors: Shai Policker, David Prutchi, Ophir Bitton, Benny Rousso, Offer Glasberg, Yuval Mika, Tami Harel, Walid Haddad, Lena Milman
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Patent number: 7512442Abstract: Apparatus is provided for treating a condition such as obesity. The apparatus includes a set of one or more electrodes, which are adapted to be applied to one or more respective sites in a vicinity of a body of a stomach of a patient. A control unit is adapted to drive the electrode set to apply to the body of the stomach a signal, configured such that application thereof increases a level of contraction of muscle tissue of the body of the stomach, and decreases a cross sectional area of a portion of the body of the stomach for a substantially continuous period greater than about 3 seconds.Type: GrantFiled: October 28, 2005Date of Patent: March 31, 2009Assignee: Metacure N.V.Inventors: Melina Flesler, Yuval Mika, Ziv Belsky, Yaakov Ben Arie, Nissim Darvish, Shlomo Ben-Haim
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Patent number: 7330753Abstract: Diet evaluation gastric apparatus (18) is provided, which detects when a patient (10) swallows, and detects the type and amount of matter ingested. The apparatus includes electrodes (74, 100) adapted to be coupled to the fundus and antrum of the patient and to measure electrical and mechanical activity therein, and a control unit (90) to analyze such electrical and mechanical activity and optionally apply electrical energy to modify the activity of tissue of the patient.Type: GrantFiled: April 16, 2002Date of Patent: February 12, 2008Assignee: Metacure N.V.Inventors: Shai Policker, Ricardo Aviv, Ophir Biton
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Publication number: 20070299320Abstract: Diet evaluation gastric apparatus (18) is provided, which detects when a patient (10) swallows, and detects the type and amount of matter ingested. The apparatus includes electrodes (74, 100) adapted to be coupled to the fundus and antrum of the patient and to measure electrical and mechanical activity therein, and a control unit (90) to analyze such electrical and mechanical activity and optionally apply electrical energy to modify the activity of tissue of the patient.Type: ApplicationFiled: August 31, 2007Publication date: December 27, 2007Applicant: METACURE N.V.Inventors: Shai Policker, Ricardo Aviv, Ophir Biton
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Publication number: 20070060812Abstract: Apparatus (18) is provided for sensing electrical activity of a pancreas (20) of a patient. The apparatus (18) includes a set of one or more electrodes (100), adapted to be coupled to the pancreas (20), and to generate activity signals indicative of electrical activity of pancreatic cells which are in a plurality of islets of the pancreas (20). The apparatus (18) also includes a control unit (90), adapted to receive the activity signals, and to generate an output signal responsive thereto.Type: ApplicationFiled: October 24, 2002Publication date: March 15, 2007Applicant: METACURE N.V.Inventors: Tamar Harel, Tamir Levi, Yuval Mika, Offer Glassberg, Nissim Darvish, Radwan Khawaled, Shimon Marom
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Publication number: 20060184207Abstract: A pancreatic controller, comprising: a glucose sensor, for sensing a level of glucose or insulin in a body serum; at least one electrode, for electrifying an insulin producing cell or group of cells; a power source for electrifying said electrode with a pulse that does not initiate an action potential in said cell and has an effect of increasing insulin secretion; and a controller which receives the sensed level and controls said power source to electrify said electrode to have a desired effect on said level.Type: ApplicationFiled: December 27, 2005Publication date: August 17, 2006Applicant: Metacure N.V.Inventors: Nissim Darvish, Tami Harel, Bella Felsen
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Publication number: 20060085045Abstract: A method of glucose level control, comprising providing at least one electrode adapted to apply an electric field to a pancreas; and applying an electric field to the pancreas using said at least one electrode such that blood glucose levels are significantly reduced and blood insulin levels are not significantly increased.Type: ApplicationFiled: September 4, 2003Publication date: April 20, 2006Applicant: Metacure N.V.Inventors: Tami Harel, Shai Policker, Radwan Khawaled, Yuval Mika, Offer Glasberg, Aharon Grossman
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Patent number: 7006871Abstract: A pancreatic controller (102), comprising: a glucose sensor (118), for sensing a level of glucose or insulin in a body serum; at least one electrode (110, 112), for electrifying an insulin producing cell or group of cells; a power source (104) for electrifying said electrode with a pulse that does not initiate an action potential in said cell and has an effect of increasing insulin secretion; and a controller (106) which receives the sensed level and controls said power source to electrify said electrode to have a desired effect on said level.Type: GrantFiled: March 5, 2000Date of Patent: February 28, 2006Assignee: Metacure N.V.Inventors: Nissim Darvish, Tami Harel, Bella Felsen
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Patent number: 6993391Abstract: Apparatus is provided for treating a condition such as obesity. The apparatus includes a set of one or more electrodes, which are adapted to be applied to one or more respective sites in a vicinity of a body of a stomach of a patient. A control unit is adapted to drive the electrode set to apply to the body of the stomach a signal, configured such that application thereof increases a level of contraction of muscle tissue of the body of the stomach, and decreases a cross-sectional area of a portion of the body of the stomach for a substantially continuous period greater than about 3 seconds.Type: GrantFiled: May 28, 2003Date of Patent: January 31, 2006Assignee: Metacure N.V.Inventors: Melina Flesler, Yuval Mika, Ziv Belsky, Yaakov Ben Arie, Nissim Darvish, Shlomo Ben-Haim