Patents Assigned to Metagenics, Inc.
  • Patent number: 11026897
    Abstract: A composition for treatment of inflammation in a mammal is provided. The mammal has a neutrophil to lymphocyte ratio (NLR). The composition includes a curcumagalactomannoside and a hops extract. The curcumagalactomannoside and the hops extract cooperate to decrease the NLR of the mammal 12 weeks after ingestion of the composition. A method of treatment of inflammation in a mammal is also provided. The method includes obtaining a parameter of the mammal. The method further includes dosing the composition based on the parameter. The method further includes administering the composition to the mammal.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: June 8, 2021
    Assignee: METAGENICS, INC.
    Inventors: Nikhat Contractor, Jennifer Joan Ryan
  • Patent number: 10751362
    Abstract: Disclosed is a prebiotic composition comprising a combination of 2?fucosyllactose (2?FL) and isomaltooligosaccharide (IMO). The 2?FL and IMO are present in the prebiotic composition in a weight ratio of from 1:1 to 1:10. The prebiotic composition is effective for use in methods of preventing and/or treating a gastrointestinal (GI) condition in an animal, such as irritable bowel syndrome (IBS), inflammatory bowel disease(s) (IBD), Crohn's disease, and ulcerative colitis (UC). A foodstuff or beverage, a medical food, a nutritional composition, and a kit presentation, each including the prebiotic composition, and each suitable for use in methods of reducing or suppressing inflammation in an animalian tract, are also disclosed. A method of using the prebiotic composition to prevent and/or treat a GI condition in an animal is further disclosed. The method comprises administering the prebiotic composition to the animal.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: August 25, 2020
    Assignee: METAGENICS, INC.
    Inventors: Sara LeBrun-Blashka, John Troup, Nikhat Contractor
  • Patent number: 7029703
    Abstract: A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, fat, and other minerals. A preferred source of vitamin D activity is cholecalciferol, and a preferred osteoblast stimulant is ipriflavone. In addition to these basic ingredients, the composition can further include various other minerals known to occur in bone, vitamin C, and glucosamine sulfate, all of which exert beneficial effects on growth and maintenance of healthy bone. A method for benefitting human bone health involves administering a daily regimen of the dietary supplement.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: April 18, 2006
    Assignee: Metagenics, Inc.
    Inventors: Kim C. Krumhar, Holly A. Johnson
  • Patent number: 6949260
    Abstract: A composition for treating inflammation and pain in mammals, particularly humans. Effective amounts of a boswellic acid, a curcuminoid, a gingerol, a capsaicinoid, a bioflavonoid, and a vitamin C source, in various combinations, all preferably from a botanical source, are blended to form a dose for oral administration. Administration of the dose provides relief from pain and inflammation of connective tissue. The dose may be administered as a tablet, a liquid, or a powder.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: September 27, 2005
    Assignee: Metagenics, Inc.
    Inventor: Kim Carleton Krumhar
  • Patent number: 6602517
    Abstract: The present invention provides dietary supplements, medical foods and methods effective to ameliorate at least one of the symptoms, preferably all of the symptoms, of an inflammation-related disease. The dietary supplements of the present invention include rosemary, curcumin and at least one component selected from the group consisting of quercetin and rutin. The medical foods of the present invention include include rosemary and at least one component selected from the group consisting of curcumin, quercetin and rutin. The medical foods of the present invention also include macronutrients. The methods of the present invention include the step of administering to a person suffering from an inflammation-related disease an effective amount of a dietary supplement or medical food of the present invention.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: August 5, 2003
    Assignee: Metagenics, Inc.
    Inventors: Gary K. Darland, Daniel O. Lukaczer, DeAnn J. Liska, Tracey A. Irving, Jeffrey S. Bland
  • Patent number: 6534086
    Abstract: A composition for treating inflammation and pain in mammals, particularly humans. Effective amounts of a boswellic acid, a curcuminoid, a gingerol, a capsaicinoid, a bioflavonoid, and a vitamin C source, in various combinations, all preferably from a botanical source, are blended to form a dose for oral administration. Administration of the dose provides relief from pain and inflammation of connective tissue. The dose may be administered as a tablet, a liquid, or a powder.
    Type: Grant
    Filed: March 6, 2000
    Date of Patent: March 18, 2003
    Assignee: Metagenics, Inc.
    Inventor: Kim Carleton Krumhar
  • Patent number: 6528502
    Abstract: A nutritional supplement for use in managing carbohydrates and enhancing anabolism in mammals is described. The nutritional supplement contains regulated amounts of niacin, chromium, and vanadium, and optionally thiamin, riboflavin, magnesium, and zinc. These vitamins and minerals mimic and/or enhance the physiological effects of insulin in the body. A method of using the composition is also described.
    Type: Grant
    Filed: August 8, 2000
    Date of Patent: March 4, 2003
    Assignee: Metagenics, Inc.
    Inventors: Kim Carleton Krumhar, Jeffrey J. Katke
  • Patent number: 6447809
    Abstract: A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, fat, and other minerals. A preferred source of vitamin D activity is cholecalciferol, and a preferred osteoblast stimulant is ipriflavone. In addition to these basic ingredients, the composition can further include various other minerals known to occur in bone, vitamin C, and glucosamine sulfate, all of which exert beneficial effects on growth and maintenance of healthy bone. A method for benefitting human bone health involves administering a daily regimen of the dietary supplement.
    Type: Grant
    Filed: May 11, 2000
    Date of Patent: September 10, 2002
    Assignee: Metagenics, Inc.
    Inventors: Kim C. Krumhar, Holly A. Johnson
  • Patent number: 6432453
    Abstract: A composition containing a stabilized form of conjugated linoleic acid is described. The conjugated linoleic acid is reacted with glycerol to form an ester, which is much more resistant to oxidation than the acid form of the conjugated linoleic acid. The composition can additionally contain antioxidants, such as rosemary leaf extract, tocopherols, chelating agents, ascorbic acid, the like. The composition can also contain a fatty acid and/or glycerol ingredient. A method for supplementing an individual's diet is also described.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: August 13, 2002
    Assignee: Metagenics, Inc.
    Inventor: Kim Carleton Krumhar
  • Patent number: 6241983
    Abstract: A composition for promoting gastrointestinal health contains an effective amount of a beneficial human intestinal microorganism and an effective amount of dietary fiber. Preferably, the dietary fiber is a member selected from the group consisting of pentosans, &bgr;-glucans, pectins and pectic polysaccharides, mannans, arabinans and galactans, fructo-oligosaccharides, and mixtures thereof. The bacteria- and fiber-containing composition can optionally contain one or more of an immunoglobulin composition containing concentrated immunologically active immunoglobulins, components of a non-immune defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. Methods of use are also described.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: June 5, 2001
    Assignee: Metagenics, Inc.
    Inventors: Stephen M. Paul, Jeffrey J. Katke, Kim Carleton Krumhar
  • Patent number: 6180099
    Abstract: A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: January 30, 2001
    Assignee: Metagenics, Inc.
    Inventor: Stephen M. Paul
  • Patent number: 5744134
    Abstract: A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: April 28, 1998
    Assignee: Metagenics, Inc.
    Inventor: Stephen M. Paul
  • Patent number: 5626883
    Abstract: A vitamin C supplement comprising ascorbic acid, ascorbyl palmitate, niacinamide ascorbate, calcium ascorbate, magnesium ascorbate, potassium ascorbate, and sodium ascorbate which together can be administered to a human to avoid the transitory initial suppression of human NK cell activity which is present when ascorbic acid alone is administered. Also included is xylitol, lysine acetate, tetrasodium pyrophosphate, ribose, cysteine, and hesperidin which further prolongs the biological activity of ascorbic acid and promotes the uptake of ascorbic acid by human tissue.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: May 6, 1997
    Assignee: Metagenics, Inc.
    Inventor: Stephen M. Paul
  • Patent number: 5531988
    Abstract: A composition for promoting gastrointestinal health comprises an effective amount of a beneficial human intestinal microorganism and an effective amount of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins. Preferred beneficial human intestinal bacteria include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: July 2, 1996
    Assignee: Metagenics, Inc.
    Inventor: Stephen M. Paul
  • Patent number: 5531989
    Abstract: A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: July 2, 1996
    Assignee: Metagenics, Inc.
    Inventor: Stephen M. Paul
  • Patent number: 5292538
    Abstract: A composition which provides for sustained energy and nutrition to support an anabolic physiological state in humans comprises a blend of simple sugars and more complex carbohydrates, partially hydrolyzed protein, and, at least, magnesium in the form of an amino acid chelate. Preferably the carbohydrate source is a blend of about 5-45% crystalline fructose and 55-95% glucose polymers by weight. Other ingredients, including lipids, bioavailable minerals in the form of amino acid chelates, anabolic nutrients, vitamins, antioxidants, and lipotropic agents may be added as desired to provide an optimal sustained energy and anabolic nutrition formulation. When administered, the carbohydrate blend, protein source, and amino acid chelates facilitate sustained energy and delivery of nutrients to appropriate sites within the body for efficient utilization in anabolic physiology.
    Type: Grant
    Filed: July 22, 1992
    Date of Patent: March 8, 1994
    Assignees: Metagenics, Inc., Albion International, Inc.
    Inventors: Stephen M. Paul, H. DeWayne Ashmead
  • Patent number: 5270297
    Abstract: A composition which provides for rehydration and endurance in persons having symptoms of physiological stress comprises a blend of simple sugars and more complex carbohydrates and, at least magnesium, in the form of an amino acid chelate. Preferably the carbohydrate source is a blend of crystalline fructose and glucose polymers in a weight ratio of between about 4:1 and 1:4. Other ingredients, including anabolic nutrients, vitamins, electrolyte ions (e.g. potassium, sodium, chloride), and other minerals, such as calcium amino acid chelate, may be added as desired to provide an optimal rehydration and endurance formulation. When administered, the carbohydrate blend and amino acid chelates facilitate rehydration and the delivery of nutrients and calorie energy to appropriate sites within the body for efficient utilization.
    Type: Grant
    Filed: July 23, 1992
    Date of Patent: December 14, 1993
    Assignee: Metagenics, Inc.
    Inventors: Stephen M. Paul, DeWayne H. Ashmead
  • Patent number: 5164384
    Abstract: The present invention is an ergogenic, anabolic mineral formula for use as a nutritional supplement, weight loss formula and cholesterol lowering agent. The formula comprises 500 mcg. of vanadyl sulfate, 100 mcg. of chromium picolinate, 100 mcg. of chromium nicotinate glycinate, and 25 mg. of niacin. The vanadyl sulfate and chromium components are used primarily to mimic and enhance the effects of insulin. The niacin component is included to cause blood vessels to dilate and to reduce cholesterol levels and thus improve the efficiency of chromium and carbohydrate utilization.
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: November 17, 1992
    Assignee: Metagenics, Inc.
    Inventor: Steven M. Paul