Patents Assigned to Metagenics, Inc.
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Patent number: 11026897Abstract: A composition for treatment of inflammation in a mammal is provided. The mammal has a neutrophil to lymphocyte ratio (NLR). The composition includes a curcumagalactomannoside and a hops extract. The curcumagalactomannoside and the hops extract cooperate to decrease the NLR of the mammal 12 weeks after ingestion of the composition. A method of treatment of inflammation in a mammal is also provided. The method includes obtaining a parameter of the mammal. The method further includes dosing the composition based on the parameter. The method further includes administering the composition to the mammal.Type: GrantFiled: August 9, 2019Date of Patent: June 8, 2021Assignee: METAGENICS, INC.Inventors: Nikhat Contractor, Jennifer Joan Ryan
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Patent number: 10751362Abstract: Disclosed is a prebiotic composition comprising a combination of 2?fucosyllactose (2?FL) and isomaltooligosaccharide (IMO). The 2?FL and IMO are present in the prebiotic composition in a weight ratio of from 1:1 to 1:10. The prebiotic composition is effective for use in methods of preventing and/or treating a gastrointestinal (GI) condition in an animal, such as irritable bowel syndrome (IBS), inflammatory bowel disease(s) (IBD), Crohn's disease, and ulcerative colitis (UC). A foodstuff or beverage, a medical food, a nutritional composition, and a kit presentation, each including the prebiotic composition, and each suitable for use in methods of reducing or suppressing inflammation in an animalian tract, are also disclosed. A method of using the prebiotic composition to prevent and/or treat a GI condition in an animal is further disclosed. The method comprises administering the prebiotic composition to the animal.Type: GrantFiled: July 17, 2017Date of Patent: August 25, 2020Assignee: METAGENICS, INC.Inventors: Sara LeBrun-Blashka, John Troup, Nikhat Contractor
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Patent number: 7029703Abstract: A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, fat, and other minerals. A preferred source of vitamin D activity is cholecalciferol, and a preferred osteoblast stimulant is ipriflavone. In addition to these basic ingredients, the composition can further include various other minerals known to occur in bone, vitamin C, and glucosamine sulfate, all of which exert beneficial effects on growth and maintenance of healthy bone. A method for benefitting human bone health involves administering a daily regimen of the dietary supplement.Type: GrantFiled: September 9, 2002Date of Patent: April 18, 2006Assignee: Metagenics, Inc.Inventors: Kim C. Krumhar, Holly A. Johnson
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Patent number: 6949260Abstract: A composition for treating inflammation and pain in mammals, particularly humans. Effective amounts of a boswellic acid, a curcuminoid, a gingerol, a capsaicinoid, a bioflavonoid, and a vitamin C source, in various combinations, all preferably from a botanical source, are blended to form a dose for oral administration. Administration of the dose provides relief from pain and inflammation of connective tissue. The dose may be administered as a tablet, a liquid, or a powder.Type: GrantFiled: March 3, 2003Date of Patent: September 27, 2005Assignee: Metagenics, Inc.Inventor: Kim Carleton Krumhar
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Patent number: 6602517Abstract: The present invention provides dietary supplements, medical foods and methods effective to ameliorate at least one of the symptoms, preferably all of the symptoms, of an inflammation-related disease. The dietary supplements of the present invention include rosemary, curcumin and at least one component selected from the group consisting of quercetin and rutin. The medical foods of the present invention include include rosemary and at least one component selected from the group consisting of curcumin, quercetin and rutin. The medical foods of the present invention also include macronutrients. The methods of the present invention include the step of administering to a person suffering from an inflammation-related disease an effective amount of a dietary supplement or medical food of the present invention.Type: GrantFiled: January 29, 2001Date of Patent: August 5, 2003Assignee: Metagenics, Inc.Inventors: Gary K. Darland, Daniel O. Lukaczer, DeAnn J. Liska, Tracey A. Irving, Jeffrey S. Bland
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Patent number: 6534086Abstract: A composition for treating inflammation and pain in mammals, particularly humans. Effective amounts of a boswellic acid, a curcuminoid, a gingerol, a capsaicinoid, a bioflavonoid, and a vitamin C source, in various combinations, all preferably from a botanical source, are blended to form a dose for oral administration. Administration of the dose provides relief from pain and inflammation of connective tissue. The dose may be administered as a tablet, a liquid, or a powder.Type: GrantFiled: March 6, 2000Date of Patent: March 18, 2003Assignee: Metagenics, Inc.Inventor: Kim Carleton Krumhar
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Patent number: 6528502Abstract: A nutritional supplement for use in managing carbohydrates and enhancing anabolism in mammals is described. The nutritional supplement contains regulated amounts of niacin, chromium, and vanadium, and optionally thiamin, riboflavin, magnesium, and zinc. These vitamins and minerals mimic and/or enhance the physiological effects of insulin in the body. A method of using the composition is also described.Type: GrantFiled: August 8, 2000Date of Patent: March 4, 2003Assignee: Metagenics, Inc.Inventors: Kim Carleton Krumhar, Jeffrey J. Katke
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Patent number: 6447809Abstract: A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, fat, and other minerals. A preferred source of vitamin D activity is cholecalciferol, and a preferred osteoblast stimulant is ipriflavone. In addition to these basic ingredients, the composition can further include various other minerals known to occur in bone, vitamin C, and glucosamine sulfate, all of which exert beneficial effects on growth and maintenance of healthy bone. A method for benefitting human bone health involves administering a daily regimen of the dietary supplement.Type: GrantFiled: May 11, 2000Date of Patent: September 10, 2002Assignee: Metagenics, Inc.Inventors: Kim C. Krumhar, Holly A. Johnson
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Patent number: 6432453Abstract: A composition containing a stabilized form of conjugated linoleic acid is described. The conjugated linoleic acid is reacted with glycerol to form an ester, which is much more resistant to oxidation than the acid form of the conjugated linoleic acid. The composition can additionally contain antioxidants, such as rosemary leaf extract, tocopherols, chelating agents, ascorbic acid, the like. The composition can also contain a fatty acid and/or glycerol ingredient. A method for supplementing an individual's diet is also described.Type: GrantFiled: February 1, 2001Date of Patent: August 13, 2002Assignee: Metagenics, Inc.Inventor: Kim Carleton Krumhar
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Patent number: 6241983Abstract: A composition for promoting gastrointestinal health contains an effective amount of a beneficial human intestinal microorganism and an effective amount of dietary fiber. Preferably, the dietary fiber is a member selected from the group consisting of pentosans, &bgr;-glucans, pectins and pectic polysaccharides, mannans, arabinans and galactans, fructo-oligosaccharides, and mixtures thereof. The bacteria- and fiber-containing composition can optionally contain one or more of an immunoglobulin composition containing concentrated immunologically active immunoglobulins, components of a non-immune defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. Methods of use are also described.Type: GrantFiled: May 26, 1999Date of Patent: June 5, 2001Assignee: Metagenics, Inc.Inventors: Stephen M. Paul, Jeffrey J. Katke, Kim Carleton Krumhar
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Patent number: 6180099Abstract: A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.Type: GrantFiled: April 17, 1998Date of Patent: January 30, 2001Assignee: Metagenics, Inc.Inventor: Stephen M. Paul
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Patent number: 5744134Abstract: A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.Type: GrantFiled: July 1, 1996Date of Patent: April 28, 1998Assignee: Metagenics, Inc.Inventor: Stephen M. Paul
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Patent number: 5626883Abstract: A vitamin C supplement comprising ascorbic acid, ascorbyl palmitate, niacinamide ascorbate, calcium ascorbate, magnesium ascorbate, potassium ascorbate, and sodium ascorbate which together can be administered to a human to avoid the transitory initial suppression of human NK cell activity which is present when ascorbic acid alone is administered. Also included is xylitol, lysine acetate, tetrasodium pyrophosphate, ribose, cysteine, and hesperidin which further prolongs the biological activity of ascorbic acid and promotes the uptake of ascorbic acid by human tissue.Type: GrantFiled: April 15, 1994Date of Patent: May 6, 1997Assignee: Metagenics, Inc.Inventor: Stephen M. Paul
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Patent number: 5531988Abstract: A composition for promoting gastrointestinal health comprises an effective amount of a beneficial human intestinal microorganism and an effective amount of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins. Preferred beneficial human intestinal bacteria include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.Type: GrantFiled: October 28, 1994Date of Patent: July 2, 1996Assignee: Metagenics, Inc.Inventor: Stephen M. Paul
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Patent number: 5531989Abstract: A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.Type: GrantFiled: May 9, 1995Date of Patent: July 2, 1996Assignee: Metagenics, Inc.Inventor: Stephen M. Paul
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Patent number: 5292538Abstract: A composition which provides for sustained energy and nutrition to support an anabolic physiological state in humans comprises a blend of simple sugars and more complex carbohydrates, partially hydrolyzed protein, and, at least, magnesium in the form of an amino acid chelate. Preferably the carbohydrate source is a blend of about 5-45% crystalline fructose and 55-95% glucose polymers by weight. Other ingredients, including lipids, bioavailable minerals in the form of amino acid chelates, anabolic nutrients, vitamins, antioxidants, and lipotropic agents may be added as desired to provide an optimal sustained energy and anabolic nutrition formulation. When administered, the carbohydrate blend, protein source, and amino acid chelates facilitate sustained energy and delivery of nutrients to appropriate sites within the body for efficient utilization in anabolic physiology.Type: GrantFiled: July 22, 1992Date of Patent: March 8, 1994Assignees: Metagenics, Inc., Albion International, Inc.Inventors: Stephen M. Paul, H. DeWayne Ashmead
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Patent number: 5270297Abstract: A composition which provides for rehydration and endurance in persons having symptoms of physiological stress comprises a blend of simple sugars and more complex carbohydrates and, at least magnesium, in the form of an amino acid chelate. Preferably the carbohydrate source is a blend of crystalline fructose and glucose polymers in a weight ratio of between about 4:1 and 1:4. Other ingredients, including anabolic nutrients, vitamins, electrolyte ions (e.g. potassium, sodium, chloride), and other minerals, such as calcium amino acid chelate, may be added as desired to provide an optimal rehydration and endurance formulation. When administered, the carbohydrate blend and amino acid chelates facilitate rehydration and the delivery of nutrients and calorie energy to appropriate sites within the body for efficient utilization.Type: GrantFiled: July 23, 1992Date of Patent: December 14, 1993Assignee: Metagenics, Inc.Inventors: Stephen M. Paul, DeWayne H. Ashmead
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Patent number: 5164384Abstract: The present invention is an ergogenic, anabolic mineral formula for use as a nutritional supplement, weight loss formula and cholesterol lowering agent. The formula comprises 500 mcg. of vanadyl sulfate, 100 mcg. of chromium picolinate, 100 mcg. of chromium nicotinate glycinate, and 25 mg. of niacin. The vanadyl sulfate and chromium components are used primarily to mimic and enhance the effects of insulin. The niacin component is included to cause blood vessels to dilate and to reduce cholesterol levels and thus improve the efficiency of chromium and carbohydrate utilization.Type: GrantFiled: June 19, 1991Date of Patent: November 17, 1992Assignee: Metagenics, Inc.Inventor: Steven M. Paul