Patents Assigned to METALLOGENICS CO., LTD.
  • Patent number: 10690648
    Abstract: To provide to a reagent composition used in quantitative measurement of lithium in aqueous solutions such as biological specimens and environmental liquid samples by a simple colorimeter or ultraviolet-visible light spectrophotometer immediately, a reagent composition which permits to measure a concentration of lithium by visual observation, and a method and apparatus for measuring lithium ion by using the reagent. A reagent composition for measuring lithium comprising F28 tetraphenylporphyrin compound as chelating agent, including further a water-soluble organic solvent, a pH modifier and a stabilizer, and a method and apparatus for measuring lithium ion by using the reagent.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: June 23, 2020
    Assignee: METALLOGENICS Co., Ltd
    Inventors: Takuya Iwabuchi, Tsugikatsu Odashima
  • Patent number: 10041887
    Abstract: A lithium reagent composition for determining lithium concentration, with which it is possible to instantaneously determine the amount of lithium contained in an aqueous solution, such as a biosample or an environmental sample, by means of a simple colorimeter or ultraviolet-visible spectrophotometer and which renders a visual assessement possible; and a method and device for quantifying lithium ions using the composition. A lithium reagent composition obtained by mixing the compound represented by the structural formula, wherein all of the hydrogen atoms bonded to carbon atoms of tetraphenylporphyrin have been replaced with fluorine atoms, as a chelating agent with a basic organic compound selected from monoethanolamine, diethanolamine, and triethanolamine and producing an aqueous solution thereof that further contains a pH regulator with which the pH has been regulated to 5 or higher; and a method and device for quantifying lithium ions using the composition.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: August 7, 2018
    Assignee: METALLOGENICS Co., Ltd
    Inventors: Hiroko Suzuki, Takuya Iwabuchi, Kazuhiro Koide, Tsugikatsu Odashima
  • Patent number: 9689794
    Abstract: To provide to a method for measuring and examining lithium ions in an aqueous solution of a specimen such as biomaterials or environment samples, by using a lithium reagent composition as a coloration reaction reagent and by visual observing or a simple a colorimeter. The lithium ions measuring method is characterized by contacting the specimen including serum and plasma test sample with an aqueous solution of a lithium reagent composition comprising a tetraphenyl porphyrin compound, a pH regulator and a pH buffer, by irradiating or expose the resulting solution with white light, and by detecting change in color tone by a visual observation or by detecting the sensitivity by a colorimeter.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: June 27, 2017
    Assignee: METALLOGENICS Co., Ltd
    Inventors: Takuya Iwabuchi, Tsugikatsu Odashima, Hiroko Suzuki
  • Publication number: 20170102371
    Abstract: To provide to a reagent composition used in quantitative measurement of lithium in aqueous solutions such as biological specimens and environmental liquid samples by a simple colorimeter or ultraviolet-visible light spectrophotometer immediately, a reagent composition which permits to measure a concentration of lithium by visual observation, and a method and apparatus for measuring lithium ion by using the reagent. A reagent composition for measuring lithium comprising F28 tetraphenylporphyrin compound as chelating agent, including further a water-soluble organic solvent, a pH modifier and a stabilizer, and a method and apparatus for measuring lithium ion by using the reagent.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 13, 2017
    Applicant: METALLOGENICS CO., LTD
    Inventors: Takuya IWABUCHI, Tsugikatsu ODASHIMA
  • Patent number: 9562886
    Abstract: [Problem] To provide to a reagent composition used in quantitative measurement of lithium in aqueous solutions such as biological specimens and environmental liquid samples by a simple colorimeter or ultraviolet-visible light spectrophotometer immediately, a reagent composition which permits to measure a concentration of lithium by visual observation, and a method and apparatus for measuring lithium ion by using the reagent. [Solution] A reagent composition for measuring lithium comprising F28 tetraphenylporphyrin compound as chelating agent, including further a water-soluble organic solvent, a pH modifier and a stabilizer, and a method and apparatus for measuring lithium ion by using the reagent.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: February 7, 2017
    Assignee: METALLOGENICS Co., Ltd
    Inventors: Takuya Iwabuchi, Tsugikatsu Odashima
  • Publication number: 20170003228
    Abstract: A lithium reagent composition for determining lithium concentration, with which it is possible to instantaneously determine the amount of lithium contained in an aqueous solution, such as a biosample or an environmental sample, by means of a simple colorimeter or ultraviolet-visible spectrophotometer and which renders a visual assessement possible; and a method and device for quantifying lithium ions using the composition. A lithium reagent composition obtained by mixing the compound represented by the structural formula, wherein all of the hydrogen atoms bonded to carbon atoms of tetraphenylporphyrin have been replaced with fluorine atoms, as a chelating agent with a basic organic compound selected from monoethanolamine, diethanolamine, and triethanolamine and producing an aqueous solution thereof that further contains a pH regulator with which the pH has been regulated to 5 or higher; and a method and device for quantifying lithium ions using the composition.
    Type: Application
    Filed: November 11, 2014
    Publication date: January 5, 2017
    Applicant: METALLOGENICS CO., LTD.
    Inventors: Hiroko SUZUKI, Takuya IWABUCHI, Kazuhiro KOIDE, Tsugikatsu ODASHIMA
  • Publication number: 20160356796
    Abstract: An Fe(II) ion detection agent, and related method, capable of fluorescently detecting Fe(II) ions quickly with high sensitivity is disclosed. The Fe(II) ion detection agent can be a compound represented by formula (I) (fluorescence probe): wherein R1 and R2 represent lower alkyl; R3 and R4 represent hydrogen; R5 represents hydrogen, hydroxyl, or a group represented by formula (A): —NR51R52 wherein R51 and R52 represent lower alkyl; R6 and R7 represent hydrogen; ring A represents an aromatic ring; V represents O or SiR10R11 wherein R10 and R11 are the same or different and represent, hydrogen or lower alkyl; W represents CH2, CO; Z represents O; m and n are the same or different and represent 0 or 1. The agent can be combined with a compound having at least three coordinating positions.
    Type: Application
    Filed: January 16, 2015
    Publication date: December 8, 2016
    Applicant: Metallogenics Co., Ltd.
    Inventors: Hideko NAGASAWA, Tasuku HIRAYAMA
  • Publication number: 20150079687
    Abstract: [Problem] To provide to a reagent composition used in quantitative measurement of lithium in aqueous solutions such as biological specimens and environmental liquid samples by a simple colorimeter or ultraviolet-visible light spectrophotometer immediately, a reagent composition which permits to measure a concentration of lithium by visual observation, and a method and apparatus for measuring lithium ion by using the reagent. [Solution] A reagent composition for measuring lithium comprising F28 tetraphenylporphyrin compound as chelating agent, including further a water-soluble organic solvent, a pH modifier and a stabilizer, and a method and apparatus for measuring lithium ion by using the reagent.
    Type: Application
    Filed: April 25, 2012
    Publication date: March 19, 2015
    Applicant: METALLOGENICS CO., LTD.
    Inventors: Takuya Iwabuchi, Tsugikatsu Odashima