Patents Assigned to Metaproteonics, LLC
  • Protein kinase modulation by hops and products
    Patent number: 8263139
    Abstract: Botanical compounds to modulate kinase activity are disclosed. The compounds and methods disclosed also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively. The compositions contain at least one fraction isolated or derived from hops or Acacia.
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: September 11, 2012
    Assignee: Metaproteonics, LLC
    Inventors: Matthew L. Tripp, John G. Babish, Linda M. Pacioretty, Jeffrey S. Bland, Amy J. Hall, Veera Konda, Anu Desai
  • Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2
    Patent number: 7279185
    Abstract: A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a curcuminoid species and an effective amount of a second component selected from the group consisting of an alpha-acid species or a beta-acid species or derivatives thereof. The composition provides synergistic anti-inflammatory effects in response to physical or chemical injury or abnormal immune stimulation due to a biological agent or unknown etiology.
    Type: Grant
    Filed: November 13, 2004
    Date of Patent: October 9, 2007
    Assignee: Metaproteonics, LLC
    Inventors: John G. Babish, Terrence M. Howell, Linda M. Pacioretty