Patents Assigned to METAVENTION, INC.
  • Neuromodulation for metabolic conditions or syndromes
    Patent number: 10856926
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: December 8, 2020
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Neuromodulation for metabolic conditions or syndromes
    Patent number: 10617460
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: April 14, 2020
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Modulation of nerves innervating the liver
    Patent number: 10543034
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: January 28, 2020
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Scott Bradley Vafai
  • Therapeutic tissue modulation devices and methods
    Patent number: 10524859
    Abstract: According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. Systems, devices and methods for cooling energy delivery members are also provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves surrounding (e.g., within adventitia of or within perivascular space of) an artery or other blood vessel, such as the common hepatic artery.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: January 7, 2020
    Assignee: Metavention, Inc.
    Inventors: Anthony Ciro Vrba, Scott Raymond Smith, Bobak Robert Azamian, James G. Hansen
  • Neuromodulation methods to alter glucose levels
    Patent number: 10070911
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: September 11, 2018
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Methods of modulating nerves of the hepatic plexus
    Patent number: 10064674
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: September 4, 2018
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Scott Bradley Vafai
  • Therapeutic denervation of nerves surrounding a hepatic vessel
    Patent number: 9999461
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: June 19, 2018
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • MODULATION OF TARGETED NERVE FIBERS
    Publication number: 20160128767
    Abstract: According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves within a wall of (e.g., within adventitia surrounding a lumen of) an artery or other blood vessel, such as the common hepatic artery.
    Type: Application
    Filed: June 4, 2014
    Publication date: May 12, 2016
    Applicant: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai, Anthony Ciro Vrba
  • Balloon catheter neuromodulation systems
    Patent number: 9265575
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: February 23, 2016
    Assignee: Metavention, Inc.
    Inventors: Jonathan Allen Coe, Bobak Robert Azamian, Scott Bradley Vafai
  • Glucose alteration methods
    Patent number: 9149329
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: October 6, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Hepatic neuromodulation using fluids or chemical agents
    Patent number: 9114123
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: August 25, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Scott Bradley Vafai
  • Modulation of nerves innervating the liver
    Patent number: 9114124
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: August 25, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Gastroduodenal artery neuromodulation
    Patent number: 9089541
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid deliver.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: July 28, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Hepatic neuromodulation using microwave energy
    Patent number: 9089542
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: July 28, 2015
    Assignee: METAVENTION, INC.
    Inventors: Bobak Robert Azamian, Scott Bradley Vafai, Jonathan Allen Coe
  • Hepatic denervation systems
    Patent number: 9060784
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: June 23, 2015
    Assignee: Metavention, Inc.
    Inventors: Jonathan Allen Coe, Bobak Robert Azamian, Scott Bradley Vafai
  • Nerve modulation to treat diabetes
    Patent number: 9033969
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: May 19, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Hepatic neuromodulation to treat fatty liver conditions
    Patent number: 9011422
    Abstract: According to some embodiments, a method of treating conditions affecting a liver of a subject is provided. The method may include delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: April 21, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Treatment of non-alcoholic fatty liver disease
    Patent number: 9005190
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: April 14, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Neuromodulation methods using balloon catheter
    Patent number: 9005191
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: April 14, 2015
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Hepatic artery nerve modulation methods
    Patent number: 8894639
    Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: November 25, 2014
    Assignee: Metavention, Inc.
    Inventors: Bobak Robert Azamian, Scott Bradley Vafai, Jonathan Allen Coe