Abstract: A gold nanoporous anodic aluminum oxide (NAAO) substrate used in coordination with a handheld Surface-Enhanced Raman Spectroscopy (SERS) device for detecting phenylalanine (Phe) in a sample collected from a subject, the gold NAAO substrate comprising a multilayered nanoporous aluminum layer; and a gold layer disposed on top of the multilayered nanoporous aluminum layer. The gold layer comprises gold nanoparticles.
Type:
Grant
Filed:
July 6, 2023
Date of Patent:
March 19, 2024
Assignee:
METGEN, INCORPORATED
Inventors:
Richard D. Shunnarah, Hugh F. Garvey, Lenzi J. Williams, Devon Fish
Abstract: A method for fabrication of a gold nanoporous anodic aluminum oxide (NAAO) substrate used in coordination with a handheld Surface-Enhanced Raman Spectroscopy (SERS) device for detecting phenylalanine (Phe) in a sample collected from a subject, the method comprising forming a three-phase system on top of a multilayered nanoporous aluminum layer of the gold NAAO substrate; injecting a cosolvent solution into the three-phase system, wherein the cosolvent solution comprises gold nanoparticles; forming a gold layer on top of the multilayered nanoporous aluminum layer, and drying the gold NAAO substrate.
Type:
Grant
Filed:
July 6, 2023
Date of Patent:
March 19, 2024
Assignee:
METGEN, INCORPORATED
Inventors:
Richard D. Shunnarah, Hugh F. Garvey, Lenzi J. Williams, Devon Fish
Abstract: A handheld Surface-Enhanced Raman Spectroscopy (SERS) device for detecting phenylalanine (Phe) in a sample collected from a subject, the device comprising a laser generator configured to produce a laser beam; a nanoporous anodic aluminum oxide (NAAO) substrate configured to receive the sample collected from the subject; and a light sensor configured to receive a light.
Type:
Grant
Filed:
August 16, 2022
Date of Patent:
September 5, 2023
Assignee:
METGEN, INCORPORATED
Inventors:
Richard D. Shunnarah, Hugh F. Garvey, Lenzi J. Williams, Devon Fish