Patents Assigned to Metrohm AG
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Publication number: 20240050925Abstract: A method for modifying a support material, in particular a polymeric support material, for use as a stationary phase in an analytical or preparative separation process. The method includes the steps of providing a support material, coating the support material with an oligoamine or polyamine and reacting the support material with a compound comprising a first functional group reactive with amines and/or hydroxy group and an ion-exchange group. Additionally a support material, a chromatography column, a method of chromatographic separation of analytes and the use of such support material.Type: ApplicationFiled: December 21, 2021Publication date: February 15, 2024Applicant: METROHM AGInventors: Alexandra ZATIRAKHA, Andrea AESCHLIMANN, Bastian BRAND, Brigitte LAMERS
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Patent number: 11712660Abstract: The invention relates to a dialysis cell for sample preparation for a chemical analysis method, in particular for ion chromatography. The dialysis cell comprises a donor channel and an acceptor channel extending parallel thereto. The donor channel and the acceptor channel are separated from each other by a selectively permeable dialysis membrane. In particular, an analyte that is dissolved in a donor solution in the donor channel can enter through the dialysis membrane into the acceptor solution in the acceptor channel. The acceptor channel has at least in some sections a volume that is smaller than the volume of the donor channel extending parallel thereto. Acceptor and donor channels are formed from half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are designed in each case as a recess in a contact surface of one of the half-cells with the dialysis membrane.Type: GrantFiled: August 10, 2018Date of Patent: August 1, 2023Assignee: Metrohm AGInventors: Markus Läubli, Wolfgang Frenzel, Inga Markeviciute, Daniel Abderhalden
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Patent number: 10737855Abstract: A closure (1) for a container comprising a connecting element (2) for connection of the closure to a container, a sealing device (3) for sealing the access to a container content and an interface (4) to an adapter having a coupling receptacle (5). The closure (1) has a delivery position and a use position. In the use position, the sealing device (3) is open. In the delivery position, the sealing device (3) is sealed in a gas and liquid fight manner.Type: GrantFiled: April 1, 2014Date of Patent: August 11, 2020Assignees: METROHM AG, SIGMA-ALDRICH INTERNATIONAL GMBHInventors: Björn Christensen, Fabian Wahl, Michael Weber, Samuel Schindler, Lukas Wilhelm
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Patent number: 7767146Abstract: Sample changer with a balance, with at least two sample carriers which can be delivered to the balance and which are located in a sample rack, the sample carrier being made and arranged in the sample rack relative to the balance such that the sample carrier can be conveyed onto a weighing surface of the balance by rotation and/or shifting of the sample rack and/or the balance. Preferably, the balance is integrated in the sample changer.Type: GrantFiled: September 2, 2005Date of Patent: August 3, 2010Assignee: Metrohm AGInventor: Peter Kirschenbuhler
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Patent number: 7753238Abstract: A volume measurement and/or metering device includes a cylinder/piston and cock system for sucking in and/or discharging liquids in a defined way, the piston being movable in relation to the cylinder for sucking in or discharging the liquid. The cylinder is mounted, together with the cylinder bottom, rotatably with respect to the cock system about an axis of rotation parallel to the cylinder longitudinal axis. The cylinder bottom bears with a sealing seat against a cock element of the cock system, the cock element having at least one duct orifice. These orifices are arranged in such a way that the at least one orifice in the cylinder bottom can be brought into congruence with the orifices of the cock element when the cylinder and the cylinder bottom are rotated. Further, the cock element is brought into a sealing closing position for simultaneously closing of all the orifices of the cylinder bottom are provided.Type: GrantFiled: February 13, 2007Date of Patent: July 13, 2010Assignee: Metrohm AGInventors: Peter Kirschenbuhler, Bjorn Christensen
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Publication number: 20090118382Abstract: The invention relates to ion-exchange materials comprising a hydrophobic support resin having grafted side chains, wherein the side chains have a surfactant-type structure and comprise ion-exchange groups, and the ion-exchange material is obtainable by radical grafting of the side chains using a radical initiator containing at least one peroxide group. By means of the surfactant-type structure and the specific radical initiator, a regiospecific and particularly uniform arrangement of the side chains on the support resin is achieved which in addition enables outstanding and uniform hydration of the ion-exchange groups. This is expressed, in particular, in improved signal asymmetries for bromide and nitrate.Type: ApplicationFiled: April 4, 2007Publication date: May 7, 2009Applicant: METROHM AGInventors: Michael Raskop, Andreas Seubert, Andreas Grimm
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Publication number: 20070194055Abstract: A volume measurement and/or metering device includes a cylinder/piston and cock system for sucking in and/or discharging liquids in a defined way, the piston being movable in relation to the cylinder for sucking in or discharging the liquid. The cylinder is mounted, together with the cylinder bottom, rotatably with respect to the cock system about an axis of rotation parallel to the cylinder longitudinal axis. The cylinder bottom bears with a sealing seat against a cock element of the cock system, the cock element having at least one duct orifice. These orifices are arranged in such a way that the at least one orifice in the cylinder bottom can be brought into congruence with the orifices of the cock element when the cylinder and the cylinder bottom are rotated. Further, means for simultaneously closing of all the orifices of the cylinder bottom are provided.Type: ApplicationFiled: February 13, 2007Publication date: August 23, 2007Applicant: METROHM AGInventors: Peter Kirschenbuhler, Bjorn Christensen
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Patent number: 7019040Abstract: The present invention relates to a process for the preparation of porous polymer particles based on acrylate and/or methacrylate, comprising the steps of provision of a reaction mixture comprising at least one monomer chosen from the group consisting of acrylate and methacrylate compounds, and at least one monoterpene as porogen and of polymerization with the formation of porous polymer particles based on acrylate and/or methacrylate. The present invention also covers the porous polymer particles based on acrylate and/or methacrylate prepared in this way.Type: GrantFiled: October 15, 2003Date of Patent: March 28, 2006Assignee: Metrohm AGInventors: Andreas Seubert, Sandra Schuetze
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Publication number: 20060045805Abstract: Sample changer with a balance, with at least two sample carriers which can be delivered to the balance and which are located in a sample rack, the sample carrier being made and arranged in the sample rack relative to the balance such that the sample carrier can be conveyed onto a weighing surface of the balance by rotation and/or shifting of the sample rack and/or the balance. Preferably, the balance is integrated in the sample changer.Type: ApplicationFiled: September 2, 2005Publication date: March 2, 2006Applicant: Metrohm AGInventor: Peter Kirschenbuhler
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Publication number: 20040253150Abstract: The invention relates to a container 1 for pourable materials, in particular powdered materials M, for use on a robot arm R, with a conveying device 3 in a cylindrical housing 2, the cylindrical housing 2 being formed as a receiving space for the material M, in which the conveying device 3 is arranged in such a way that it can be driven in both directions transversely in relation to the longitudinal axis of the conveying device for receiving and discharging the material M.Type: ApplicationFiled: May 19, 2004Publication date: December 16, 2004Applicant: Metrohm AGInventor: Peter Kirschenbuhler
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Publication number: 20040082749Abstract: The present invention relates to a process for the preparation of porous polymer particles based on acrylate and/or methacrylate, comprising the steps of provision of a reaction mixture comprising at least one monomer chosen from the group consisting of acrylate and methacrylate compounds, and at least one monoterpene as porogen and of polymerization with the formation of porous polymer particles based on acrylate and/or methacrylate. The present invention also covers the porous polymer particles based on acrylate and/or methacrylate prepared in this way.Type: ApplicationFiled: October 15, 2003Publication date: April 29, 2004Applicant: Metrohm AGInventors: Andreas Seubert, Sandra Schuetze
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Patent number: 6182517Abstract: A burette tip (1) for metering a titrating agent consists essentially of a burette body (10) with a seat (3) for a membrane and with such a membrane (2). The burette tip (1) comprises, for protecting the membrane (2) and the seat (3) against mechanical damage, a covering (4, 5, 15) which at least partly encloses and covers the membrane (2) and the seat (3). The membrane (2) is clamped between the burette body (10) and a cover part (5) and is held in the burette body (10).Type: GrantFiled: August 27, 1998Date of Patent: February 6, 2001Assignee: Metrohm AGInventor: Paul Zähner
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Patent number: 6153101Abstract: In order to regenerate a plurality of suppressors (6, 6a, 6b) that are inserted alternatingly into a device for ion-exchange chromatography, apart from an analysis branch (9), at least one additional treatment branch (10, 10a) is anticipated, through which a treatment agent (7, 7a) can be fed. The analysis branch (9) and the treatment branch (10, 10a) each possess a gap (34) in which the suppressors (6, 6a, 6b) can be alternatingly inserted. In order to insert a suppressor in a pipework branch, the suppressor is moved relative to the pipework branch until the connection openings (36a, 36b) of the suppressor are aligned with the corresponding pipe openings (35) of the gap of the pipework branch concerned.Type: GrantFiled: January 11, 1996Date of Patent: November 28, 2000Assignee: Metrohm AGInventors: Helwig Schafer, Markus Laubli, Paul Zahner
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Patent number: 5861097Abstract: From an analysis probe to be analyzed, impurities such as proteins or solid matter are separated from the analytes to be analyzed by way of dialysis. An analysis solution containing the analytes is separated from an acceptor solution by a membrane of a dialysis cell. The membrane is chosen such that the analytes diffuse from the analysis solution through the membrane into the acceptor solution. In order to maintain as high as possible concentration of analytes in the acceptor solution, the analysis solution is constantly renewed. The acceptor solution remains stationary in an acceptor chamber until the concentration of analytes in the acceptor solution has reached a predetermined value, for example 95%.Type: GrantFiled: July 18, 1997Date of Patent: January 19, 1999Assignee: Metrohm AGInventors: Helwig Schafer, Wolfgang Frenzel
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Patent number: 5686829Abstract: During voltammetric analysis of liquids, the indicator electrode must be frequently changed in order to prevent memory effects and resultant changes to basic conditions during measurement. In order to be able to change the indicator electrodes simply, a plurality of indicator electrodes are arranged on a common carrier. For accommodation of the liquid (2) to be analysed, a vessel (1) is provided and the carrier (5) is mounted to move in relation to this vessel (1) in such a way that one of the indicator electrodes (6) can be selectively brought into the area intended for the liquid. The reference electrode (8) necessary for the measurement is arranged in the vessel (1) and likewise connected with the measuring device (20). With that, changing of the selected electrode (6) ensues by moving the carrier (5) relative to said vessel (1).Type: GrantFiled: May 18, 1995Date of Patent: November 11, 1997Assignee: Metrohm AGInventor: Hubert Girault
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Patent number: 5062547Abstract: A volume measurement and dosage device possesses a cylinder- piston- and valve-system (4). With this system, liquid can be drawn up and/or delivered in defined quantities. At least two channels (33, 36, 38) are provided in the valve-system, which can be connected with at least one opening (32) in the cylinder bottom (11). The piston (12) is displaceable within the cylinder (10) by means of an actuation device (3). The cylinder (10) is at the same time surrounded by a holding device (5, 40), in which it is mounted in bearings to rotate with the cylinder bottom (11) around an axis common to the longitudinal axis of the cylinder (Y) or parallel to it. The cylinder bottom (11), with at least two channel openings (29, 30, 31), rests with a sealed seating upon a valve element (28). Through rotation of the cylinder bottom (11), its opening (32) can alternately be aligned with the channel openings (29, 30, 31) of the valve element (28).Type: GrantFiled: May 9, 1990Date of Patent: November 5, 1991Assignee: Metrohm AGInventors: Paul Zahner, Karl Kaempf
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Patent number: 4715237Abstract: The chamber (1) of the metering apparatus is defined by the inside wall surface of a cylinder (3), by a displaceable piston (4), and by a cylinder end portion (5) which is displaceable relative to the cylinder (3). Ducts (2a, 2b) are arranged in the cylinder end portion (5) in such a way that they can be selectively communicated with the chamber (1) or closed off by the end face (7) of the cylinder (3) In that way a part of the chamber wall acts directly as a shut-off member so that no residual volumes remain, which cannot be ejected by the piston (4).Type: GrantFiled: February 12, 1986Date of Patent: December 29, 1987Assignee: Metrohm AGInventors: Karl Kaempf, Paul Zaehner, Wolfgang Richter