Abstract: Subject of the present invention is a combination of nucleic acid molecules capable of hybridizing with a target nucleic acid sequence. In order to overcome problems with the reproducibility of FISH assays and to decrease assay time, hairpin probes are used in combination with helper probes annealing adjacent to the target site of the hairpin probe.
Type:
Grant
Filed:
January 9, 2014
Date of Patent:
January 9, 2024
Assignee:
MIACOM DIAGNOSTICS GMBH
Inventors:
Ian Peter Thrippleton, Walter Freiherr Von Stein
Abstract: The invention concerns a composition comprising TCEP, biotin and dextran suitable for liquefying a viscous biological sample. The composition according to the invention can be used in diagnostic methods, preferably for use in diagnosis of an infection with a micro-organism, more preferably for use in diagnosis of HCAP.
Abstract: The invention concerns a composition comprising TCEP, biotin and dextran suitable for liquefying a viscous biological sample. The composition according to the invention can be used in diagnostic methods, preferably for use in diagnosis of an infection with a micro-organism, more preferably for use in diagnosis of HCAP.
Abstract: Subject of the present invention is a method for detection of an antibiotic resistance in a micro-organism comprising the steps of exposing suspected micro-organism to a labelled (fluorescent) antibiotic and observing the differences between it and a non-resistant micro-organism of the same type.
Type:
Grant
Filed:
January 30, 2009
Date of Patent:
May 14, 2013
Assignee:
miacom Diagnostics GmbH
Inventors:
Ian Thrippleton, Walter von Freiherr Stein
Abstract: Subject of the present invention is a combination of nucleic acid molecules capable of hybridising with a target nucleic acid sequence. In order to overcome problems with the reproducibility of FISH assays and to decrease assay time, hairpin probes are used in combination with helper probes annealing adjacent to the target site of the hairpin probe.
Type:
Application
Filed:
March 4, 2011
Publication date:
February 14, 2013
Applicant:
MIACOM DIAGNOSTICS GMBH
Inventors:
Ian Peter Thrippleton, Walter Freiherr Von Stein
Abstract: Subject of the present invention is a method for detection of an antibiotic resistance in a micro-organism comprising the steps of exposing suspected micro-organism to a labelled (fluorescent) antibiotic and observing the differences between it and a non-resistant micro-organism of the same type.