Patents Assigned to Michigan Critical Care Consultants, Inc.
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Patent number: 11541157Abstract: Membrane oxygenators useful in a variety of medical situations, including various short-term procedures and relatively longer-term life support, and components of membrane-based oxygenators, such as conditioning modules for exchanging oxygen for carbon dioxide during extracorporeal conditioning of blood, are described. A conditioning module includes a plurality of mats of hollow fibers and a potting material disposed throughout the peripheral edges of the mats to create a circumferential seal that defines a passageway through the plurality of fiber mats having a substantially circular cross-sectional shape. The circumferential seal defines an effective fiber length for each of the hollow fibers. A resisting member is disposed across the proximal ends of at least some of the hollow fibers and is adapted to resist fluid flow into each of the hollow fibers based on the effective fiber length of the particular hollow fiber.Type: GrantFiled: June 17, 2020Date of Patent: January 3, 2023Assignee: Michigan Critical Care Consultants, Inc.Inventors: Christopher J. Plott, Raymond DiTullio, Robert L. Beane, III
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Patent number: 11524138Abstract: Catheter and catheter assemblies for extracorporeal circulation of body fluids, such as blood, are described. A catheter includes a septum that divides an internal lumen into fluidicly isolated drainage and infusion lumens. The infusion lumen extends along only a portion of the axial length of the catheter and terminates at an infusion opening defined by the circumferential wall of the elongate member of the catheter. The drainage lumen extends the full axial length of the catheter and is laterally accessible via first and second sets of drainage openings.Type: GrantFiled: June 27, 2018Date of Patent: December 13, 2022Assignee: Michigan Critical Care Consultants, Inc.Inventor: Kenneth Jonkman
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Publication number: 20210030940Abstract: Membrane oxygenators useful in a variety of medical situations, including various short-term procedures and relatively longer-term life support, and components of membrane-based oxygenators, such as conditioning modules for exchanging oxygen for carbon dioxide during extracorporeal conditioning of blood, are described. A conditioning module includes a plurality of mats of hollow fibers and a potting material disposed throughout the peripheral edges of the mats to create a circumferential seal that defines a passageway through the plurality of fiber mats having a substantially circular cross-sectional shape. The circumferential seal defines an effective fiber length for each of the hollow fibers. A resisting member is disposed across the proximal ends of at least some of the hollow fibers and is adapted to resist fluid flow into each of the hollow fibers based on the effective fiber length of the particular hollow fiber.Type: ApplicationFiled: June 17, 2020Publication date: February 4, 2021Applicant: Michigan Critical Care Consultants, Inc.Inventors: Christopher J. Plott, Raymond DiTullio, Robert L. Beane, III
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Patent number: 10898633Abstract: The disclosure relates to devices and methods for extracorporeal conditioning of blood. Extracorporeal blood oxygenators and blood oxygenator components, such as conditioning modules, are described. An extracorporeal blood oxygenator includes a conditioning module having an external frame, an inlet cover, an outlet cover, and an internal chamber. A fiber assembly is disposed within the internal chamber and a potting material on the fiber assembly creates a circumferential seal that defines a passageway through the fiber assembly having a substantially circular cross-sectional shape. A fluid inlet is in fluid communication with the passageway, has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly, and has an internal curvilinear surface adjacent the fiber assembly. A fluid outlet on the opposite side of the fiber assembly also has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly.Type: GrantFiled: September 22, 2017Date of Patent: January 26, 2021Assignee: Michigan Critical Care Consultants, Inc.Inventors: Christopher J Plott, Robert L Beane, III
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Publication number: 20200360591Abstract: The disclosure relates to devices and methods for extracorporeal conditioning of blood. Extracorporeal blood oxygenators and blood oxygenator components, such as conditioning modules, are described. An extracorporeal blood oxygenator includes a conditioning module having an external frame, an inlet cover, an outlet cover, and an internal chamber. A fiber assembly is disposed within the internal chamber and a potting material on the fiber assembly creates a circumferential seal that defines a passageway through the fiber assembly having a substantially circular cross-sectional shape. A fluid inlet is in fluid communication with the passageway, has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly, and has an internal curvilinear surface adjacent the fiber assembly. A fluid outlet on the opposite side of the fiber assembly also has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly.Type: ApplicationFiled: August 3, 2020Publication date: November 19, 2020Applicant: Michigan Critical Care Consultants, Inc.Inventors: Christopher J Plott, Robert L. Beane, III
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Publication number: 20200171274Abstract: Catheter and catheter assemblies for extracorporeal circulation of body fluids, such as blood, are described. A catheter includes a septum that divides an internal lumen into fluidicly isolated drainage and infusion lumens. The infusion lumen extends along only a portion of the axial length of the catheter and terminates at an infusion opening defined by the circumferential wall of the elongate member of the catheter. The drainage lumen extends the full axial length of the catheter and is laterally accessible via first and second sets of drainage openings.Type: ApplicationFiled: June 27, 2018Publication date: June 4, 2020Applicant: Michigan Critical Care Consultants, Inc.Inventor: Kenneth Jonkman
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Patent number: 8678792Abstract: A roller pump conduit defining a pump chamber is provided. The roller pump conduit includes a roller contact portion having a fill region and a delivery region. The fill region has a first taper configured to determine volume delivery per revolution of a roller head. The delivery region has a pressure region having a second taper and a discharge region having a third taper. The third taper has a lesser degree of taper than the second taper. The delivery region is configured to produce a pulsatile flow out of the conduit. Furthermore, a roller pump having a roller pump conduit is provided. The roller pump conduit of the roller pump has a fill region and a delivery region, the fill region having a first taper, and the delivery region having a second and third taper, wherein the third taper has lesser degree of taper than the second taper.Type: GrantFiled: April 17, 2012Date of Patent: March 25, 2014Assignee: Michigan Critical Care Consultants, Inc.Inventors: Daniel E. Mazur, Scott I. Merz, Kathryn R. Osterholzer
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Patent number: 8568289Abstract: A system and method for controlling extracorporeal blood flow in a patient. The system includes a blood pump having a rotor, a plurality of rollers carried by the rotor and a pump chamber extended in tension about the rollers. A sensor measures an operating parameter of the blood pump and a controller, coupled to the sensor, calculates the flow efficiency of the blood pump based on the measured operating parameter. The controller is further configured to display the flow efficiency on the display device, and the operation of the blood pump is adjusted based on the flow efficiency when necessary.Type: GrantFiled: May 22, 2012Date of Patent: October 29, 2013Assignee: Michigan Critical Care Consultants, Inc.Inventor: Daniel E. Mazur
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Patent number: 8226591Abstract: A system and method for controlling extracorporeal blood flow in a patient. The system includes a blood pump having a rotor, a plurality of rollers carried by the rotor and a pump chamber extended in tension about the rollers. A sensor measures an operating parameter of the blood pump and a controller, coupled to the sensor, calculates the flow efficiency of the blood pump based on the measured operating parameter. The controller is further configured to display the flow efficiency on the display device, and the operation of the blood pump is adjusted based on the flow efficiency when necessary.Type: GrantFiled: August 5, 2009Date of Patent: July 24, 2012Assignee: Michigan Critical Care Consultants, Inc.Inventor: Daniel E. Mazur
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Patent number: 8162634Abstract: A roller pump conduit defining a pump chamber is provided. The roller pump conduit includes a roller contact portion having a fill region and a delivery region. The fill region has a first taper configured to determine volume delivery per revolution of a roller head. The delivery region has a pressure region having a second taper and a discharge region having a third taper. The third taper has a lesser degree of taper than the second taper. The delivery region is configured to produce a pulsatile flow out of the conduit. Furthermore, a roller pump having a roller pump conduit is provided. The roller pump conduit of the roller pump has a fill region and a delivery region, the fill region having a first taper, and the delivery region having a second and third taper, wherein the third taper has a lesser degree of taper than the second taper.Type: GrantFiled: December 1, 2006Date of Patent: April 24, 2012Assignee: Michigan Critical Care Consultants, Inc.Inventors: Daniel E. Mazur, Scott I. Merz, Kathryn R. Osterholzer
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Publication number: 20090287072Abstract: The disclosure provides for a biocompatible, thromboresistant coating including a chalcogenide compound that induces nitric oxide formation; and a biocompatible matrix incorporating the chalcogenide compound. Devices incorporating such coatings, and methods of making and using such coatings are also disclosed herein.Type: ApplicationFiled: December 1, 2006Publication date: November 19, 2009Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, MICHIGAN CRITICAL CARE CONSULTANTS, INC. (MC3)Inventors: Mark E. Meyerhoff, Wansik Cha, Sang-Yeul Hwang, Melissa M. Reynolds
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Patent number: 6682698Abstract: An apparatus for exchanging gases in a liquid is provided. Preferably, the apparatus comprises a housing, a first inlet, a gas exchange medium, a separator, a first outlet, and a second inlet and outlet. The apparatus may further comprise a circumferential collection gap that collects liquid from the gas exchange medium and directs it toward the first outlet. Also, the apparatus may further comprise a compliant chamber positioned near the first inlet. The compliant chamber reduces the overall impedance of the apparatus. The apparatus is particularly well-suited for use as an implantable, artificial lung. In this embodiment, the liquid comprises blood and the apparatus exchanges supplied oxygen for waste carbon dioxide.Type: GrantFiled: August 23, 2001Date of Patent: January 27, 2004Assignee: Michigan Critical Care Consultants, Inc.Inventors: Sean D. Chambers, Jean P. Montoya
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Patent number: 5810759Abstract: A control system for regulating oxygen and carbon dioxide concentrations of blood in an ECLS circuit connected to a patient. The control system includes a gas analyzer that determines the concentrations of carbon dioxide in the blood being withdrawn from the patient and of the oxygen in blood being returned to the patient. The analyzer provides concentration signals corresponding to these concentrations to a system controller. The system controller is also inputted with setpoint values for these concentrations. Utilizing control algorithm, the system controller calculates gas flow control and blood flow control signals based on the differences of the concentration signals and the setpoint values. A gas flow controller coupled to the system controller receives the gas flow control signal provides gas from a gas source to the ECLS circuit at a predetermined rate in response thereto.Type: GrantFiled: March 27, 1997Date of Patent: September 22, 1998Assignee: Michigan Critical Care Consultants, Inc.Inventor: Scott I. Merz
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Patent number: 5698161Abstract: A gas permeable membrane including a plurality of conduit members which are formed of a gas permeable material, The conduit members are unitarily formed with one another and oriented to intersect one another and define a multidimensional array. Defined within each conduit member is an interior passageway and these passageways intersect and are in communication with each other. Also disclosed are methods of manufacturing the membrane and devices incorporating the membrane.Type: GrantFiled: August 26, 1996Date of Patent: December 16, 1997Assignee: Michigan Critical Care Consultants, Inc.Inventor: Jean P. Montoya
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Patent number: 5512042Abstract: A blood reservoir which includes a primary reservoir that smoothly transitions into an outlet reservoir located beneath the primary reservoir. An inlet port permits the inflow of blood into the reservoir and an outlet port permits blood to flow out of the outlet reservoir. The primary reservoir defines an upper cavity that has first average cross sectional flow area. The outlet reservoir defines a lower cavity that has a second average cross sectional flow area which is preferably not more than one-half of the first average cross sectional flow area. The outlet reservoir therefore exhibits an increased sensitivity to blood level changes in the reservoir. The reservoir further includes features which inhibit the flow of blood from the outlet reservoir if the volume of blood in the outlet reservoir is reduced to a predetermined safety level.Type: GrantFiled: May 20, 1994Date of Patent: April 30, 1996Assignee: Michigan Critical Care Consultants, Inc.Inventors: Jean P. Montoya, Scott I. Merz
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Patent number: 5486099Abstract: A peristaltic pump having a pump conduit with an occlusive inlet segment. The pump includes a frame with rollers carried by rotor and rotated by a motor. A flexible conduit having an inlet end and an outlet end is positioned around the rollers and includes an occlusive segment and non-occlusive segment. In its free condition, the occlusive segment is collapsed and the passageway through it substantially completely occluded when the pressure within the occlusive segment is equal to or less than pressure acting on the outside of the occlusive segment. The non-occlusive segment is mildly biased to exhibit an inflated condition with an open passage when in its free condition with the pressure within the non-occlusive segment equal to pressure acting on the outside of the non-occlusive segment.Type: GrantFiled: December 14, 1994Date of Patent: January 23, 1996Assignee: Michigan Critical Care Consultants, Inc.Inventor: Jean P. Montoya