Patents Assigned to Microbiologica Quimica E Farmaceutical Ltd.
  • Methods of manufacture of 2?-deoxy-?-L-nucleosides
    Patent number: 7582748
    Abstract: The present invention relates to the synthesis of 2?-deoxy-?-L-thymidine, 2?-deoxy-?-L-uridine and 2?-deoxy-?-L-cytidine, and their derivatives, such as the 3?-O-acyl or 3?,5?-O-diacyl prodrugs, including the 3?-O-L-aminoacyl and 3?,5?-O-L-diaminoacyl prodrugs, and particularly the 3?-O-L-valinyl and 3?,5?-O-L-divalinyl prodrugs.
    Type: Grant
    Filed: March 22, 2004
    Date of Patent: September 1, 2009
    Assignee: Microbiologica Quimica E Farmaceutical Ltd.
    Inventor: Jaime A. Rabi